Results 1 to 10 of about 484,106 (362)
Inhaled corticosteroids (ICS) are the most effective controllers of asthma. They suppress inflammation mainly by switching off multiple activated inflammatory genes through reversing histone acetylation via the recruitment of histone deacetylase 2 (HDAC2)
Peter J. Barnes
doaj +5 more sources
Role of Corticosteroids in Drug-Induced Liver Injury. A Systematic Review
Introduction: Apart from cessation of the implicated agent leading to drug-induced liver injury (DILI), there is no standard therapy for DILI. Corticosteroids have been used in DILI, although their efficacy is unclear.
Einar S Björnsson+2 more
exaly +3 more sources
Renal Vein Thrombosis in Idiopathic Thrombocytopenic Purpura [PDF]
Renal Vein Thrombosis (RVT) is thrombotic occlusion of one or both main renal veins, resulting in acute or chronic kidney disease. The clinical presentation of RVT depends on the degree of venous occlusion.
Subodh Kumar Das+4 more
doaj +1 more source
Wogonin Hampers Dexamethasone-Induced Oxidative Imbalance in Sprague Dawely Rats
Corticosteroids are frequently used for their powerful anti-inflammatory activity in the management of various chronic inflammatory diseases. They are also used because of their potent immunosuppressive power in the manipulation of adverse effects ...
Maha Magdy Hassanin+4 more
doaj +1 more source
Drug Utilisation Study in Paediatric Patients with Acute Exacerbation of Bronchial Asthma Hospitalised in a Tertiary Care Teaching Hospital [PDF]
Introduction: Bronchial asthma is a heterogenous disease in children. It often leads to acute exacerbations resulting in increased Emergency Department (ED) visits, hospital admissions and school absenteeism among them.
Sukhmeen Kaur, Bhagya M Sattigeri
doaj +1 more source
Background: The efficacy and safety of corticosteroids and immunosuppressive therapy remain controversial for the treatment of immunoglobulin A nephropathy (IgAN).
Aiya Qin+10 more
doaj +1 more source
Steroids in pediatric eosinophilic esophagitis [PDF]
Swallowed fluticasone and oral viscous budesonide are effective first-line therapies for eosinophilic esophagitis in children. Side effects are minimal without evidence of Cushing syndrome, as seen in treatment with systemic corticosteroids.
Contreras, Emily M., Gupta, Sandeep K.
core +1 more source
Eosinophilic fasciitis: a case series with an emphasis on therapy and induction of remission
Eosinophilic fasciitis is an uncommon connective tissue disorder that affects patients of all ages, resulting in significant morbidity. Systemic corticosteroids can induce remission of disease.
Rechelle Tull+4 more
doaj +1 more source
Immediate-Type Hypersensitivity to Succinylated Corticosteroids [PDF]
Background: Despite their frequent use, systemic corticosteroids have rarely elicited immediate-type reactions. Objective: We report two male patients, aged 26 and 70 years, respectively, with severe immediate-type hypersensitivity secondary to the ...
Przybilla, Bernhard+3 more
core +1 more source
Validation of the Human Ozone Challenge Model as a Tool for Assessing Anti-Inflammatory Drugs in Early Development [PDF]
This study aimed to test the utility of the ozone challenge model for profiling novel compounds designed to reduce airway inflammation. The authors used a randomized, doubledummy, double-blind, placebo-controlled 3-period crossover design alternating ...
Gibson, Anthony+9 more
core +1 more source