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Inhaled Corticosteroids [PDF]

open access: yesPharmaceuticals, 2010
Inhaled corticosteroids (ICS) are the most effective controllers of asthma. They suppress inflammation mainly by switching off multiple activated inflammatory genes through reversing histone acetylation via the recruitment of histone deacetylase 2 (HDAC2)
Peter J. Barnes
doaj   +5 more sources

Antenatal Corticosteroids and Respiratory Distresses Outcome in Preterm Neonates [PDF]

open access: yesIranian Journal of Neonatology, 2021
Background: The value of antenatal corticosteroid regimen in lessening respiratory distress risk in preterm neonates has been well known, and accordingly, antenatal corticosteroid therapy was recommended for any pregnant woman likely to deliver between ...
Fatma Mohamed   +2 more
doaj   +1 more source

Efficacy and safety profile of corticosteroids and non-steroidal anti-inflammatory drugs in COVID-19 management: A narrative review

open access: yesFrontiers in Pharmacology, 2022
Due to the fact that coronavirus disease 2019 (COVID-19) is still prevalent, and current reports show that some parts of the world have seen increase in incidence, it is relevant that health professionals and scientists know about recent or novel trends,
Seth Kwabena Amponsah   +3 more
doaj   +1 more source

Abrogation of neutrophil inflammatory pathways and potential reduction of neutrophil-related factors in COVID-19 by intravenous immunoglobulin

open access: yesFrontiers in Immunology, 2022
Pathogenesis of lung injury in COVID-19 is not completely understood, leaving gaps in understanding how current treatments modulate the course of COVID-19.
Jorge Adrian Masso-Silva   +12 more
doaj   +1 more source

Atypical Stevens–Johnson syndrome caused by pembrolizumab in the treatment of metastatic melanoma – Are corticosteroids a safe treatment option?

open access: yesJournal of Dermatology and Dermatologic Surgery, 2020
Pembrolizumab is a humanized monoclonal antibody that targets programmed cell death receptor-1. Stevens–Johnson syndrome (SJS) secondary to pembrolizumab has rarely been described in the treatment of malignant melanoma (MM). A 62-year-old woman developed
Cathal O'Connor   +2 more
doaj   +1 more source

Respiratory virus type to guide predictive enrichment approaches in the management of the first episode of bronchiolitis: A systematic review

open access: yesFrontiers in Immunology, 2022
It has become clear that severe bronchiolitis is a heterogeneous disease; even so, current bronchiolitis management guidelines rely on the one-size-fits-all approach regarding achieving both short-term and chronic outcomes.
Dominika Ambrożej   +16 more
doaj   +1 more source

Renal failure in thalassemia: Thinking outside the box

open access: yesClinical Case Reports, 2020
Berger’s disease should be considered an imperative cause of renal dysfunction in thalassemia. This case highlights the importance of early diagnosis, clinicopathological correlation and prompt therapy in Berger's disease.
Ganesh Kasinathan
doaj   +1 more source

Addison’s Disease Mimicking as Acute Pancreatitis: A Case Report [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2017
Over past two decades there has been significant improvement in medical field in elucidating the underlying pathophysiology and genetics of Addison’s disease.
Sayani Chaudhuri   +4 more
doaj   +1 more source

Steroids in pediatric eosinophilic esophagitis [PDF]

open access: yes, 2014
Swallowed fluticasone and oral viscous budesonide are effective first-line therapies for eosinophilic esophagitis in children. Side effects are minimal without evidence of Cushing syndrome, as seen in treatment with systemic corticosteroids.
Contreras, Emily M., Gupta, Sandeep K.
core   +1 more source

Multiple sclerosis, relapses, and the mechanism of action of adrenocorticotropic hormone (ACTH)

open access: yesFrontiers in Neurology, 2013
Relapses in multiple sclerosis (MS) are disruptive and frequently disabling for patients, and their treatment is often a challenge to clinicians. Despite progress in the understanding of the pathophysiology of MS and development of new treatments for ...
Amy ePerrin Ross   +3 more
doaj   +1 more source

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