Immediate-Type Hypersensitivity to Succinylated Corticosteroids [PDF]
Background: Despite their frequent use, systemic corticosteroids have rarely elicited immediate-type reactions. Objective: We report two male patients, aged 26 and 70 years, respectively, with severe immediate-type hypersensitivity secondary to the ...
Przybilla, Bernhard+3 more
core +1 more source
Tinea incognito due to Trichophyton mentagrophytes: case report
Resumen Las tiñas son infecciones frecuentes causadas por dermatofitos, capaces de invadir tejido queratinizado, produciendo placas anulares, eritematosas y descamativas.
Walter Gubelin
doaj +1 more source
An in silico drug repurposing pipeline to identify drugs with the potential to inhibit SARS-CoV-2 replication [PDF]
Drug repurposing provides an opportunity to redeploy drugs, which ideally are already approved for use in humans, for the treatment of other diseases. For example, the repurposing of dexamethasone and baricitinib has played a crucial role in saving patient lives during the ongoing SARS-CoV-2 pandemic.
arxiv +1 more source
Antiviral treatment for Bell's palsy (idiopathic facial paralysis) [PDF]
BACKGROUND: Antiviral agents against herpes simplex virus are widely used in the treatment of idiopathic facial paralysis (Bell's palsy), but their effectiveness is uncertain. Significant morbidity can be associated with severe cases.
Abiko+47 more
core +2 more sources
Recovery from repeated sudden hearing loss in a patient with Takayasu’s arteritis treated with hyperbaric oxygen therapy: the first report in the literature [PDF]
Hearing loss has been rarely reported in Takayasu's arteritis, presents as sudden sensorineural hearing loss and usually responds well to corticosteroid therapy.
ALTISSIMI, Giancarlo+8 more
core +3 more sources
Corticosteroids for all adult patients with community-acquired pneumonia?
Corticosteroid therapy as adjunctive treatment in community-acquired pneumonia (CAP) is a promising but controversial subject. The potentially beneficial effect of corticosteroids is based on the ability of steroids to dampen an excessive inflammatory ...
Ger Rijkers+3 more
doaj +1 more source
Dexamethasone implant – An update
Uveitic entities may be infectious or noninfectious in etiology. Corticosteroids remain the first-line treatment for noninfectious posterior uveitis.
Richa Pyare, Jyotirmay Biswas
doaj +1 more source
Regular treatment with salmeterol and inhaled steroids for chronic asthma: serious adverse events [PDF]
Epidemiological evidence has suggested a link between beta(2)-agonists and increased asthma mortality. There has been much debate about possible causal links for this association, and whether regular (daily) long-acting beta(2)-agonists are safe ...
Altman+74 more
core +1 more source
Eosinophilic fasciitis: a case series with an emphasis on therapy and induction of remission
Eosinophilic fasciitis is an uncommon connective tissue disorder that affects patients of all ages, resulting in significant morbidity. Systemic corticosteroids can induce remission of disease.
Rechelle Tull+4 more
doaj +1 more source
Validation of the Human Ozone Challenge Model as a Tool for Assessing Anti-Inflammatory Drugs in Early Development [PDF]
This study aimed to test the utility of the ozone challenge model for profiling novel compounds designed to reduce airway inflammation. The authors used a randomized, doubledummy, double-blind, placebo-controlled 3-period crossover design alternating ...
Gibson, Anthony+9 more
core +1 more source