Results 81 to 90 of about 469,630 (315)

Low Incidence of Relapses After Vaccination in Anti‐Aquaporin‐4 Antibody‐Positive NMOSD

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Patients with neuromyelitis optica spectrum disorder (NMOSD) may experience increased signs and symptoms of their underlying disease when vaccinated against meningococcal disease before receiving complement component 5 inhibitor therapies. This retrospective analysis indicated an overall low relapse incidence (mean [range], 3.3% [0.7%–10.6 ...
Sean J. Pittock, Jin Nakahara, Becky Parks, Kerstin Allen, Sami Fam   +4 more
wiley   +1 more source

Management Challenges of Refractory Immune Thrombocytopenia during Pregnancy: A Case Report [PDF]

Journal of Clinical and Diagnostic Research
Thrombocytopenia, characterised by a platelet count below 150,000/μL, affects 7-11% of pregnancies for various reasons. Immune Thrombocytopenia (ITP), with platelet counts under 100,000/μL, accounts for 1-4% of pregnancy-related thrombocytopenia cases ...
R Akshaya, Aboobacker Mohammed Rafi, Deepak Charles   +2 more
doaj   +1 more source

The use of inhaled corticosteroids in wheezy pre-school age children : current practice and literature review [PDF]

, 2007
Preschool children and infants frequently suffer wheezy episodes, mostly associated with viral respiratory tract infections. There is no evidence to support the use of maintenance low dose inhaled corticosteroids to prevent or manage episodic mild wheeze
Vella, Cecil
core  

Normal‐Appearing White Matter Injury Mediates Chronic Deep Venous Hypoxia and Disease Progression in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore how cerebral hypoxia and Normal‐Appearing White Matter (NAWM) integrity affect MS lesion burden and clinical course. Methods Seventy‐nine MS patients, including 13 clinically isolated syndrome (CIS) patients and 66 relapsing–remitting multiple sclerosis (RRMS) patients, and 44 healthy controls (HCs) were recruited from ...
Xinli Wang, Huiying Wang, Zhizheng Zhuo, Ai Guo, Ke Lv, Decai Tian, Chao Chai, Yunyun Duan, Shuang Xia   +8 more
wiley   +1 more source

Activity of different desoximetasone preparations compared to other topical corticosteroids in the vasoconstriction assay [PDF]

, 2008
Introduction: We report on a double-blind, vehicle-controlled, single-center confirmatory study with random assignment. The purpose of the study was to investigate the topical bioavailability of different topical corticosteroid formulations in healthy ...
Ashton RE, C. Borelli, Gorne RC, H.C. Korting, Hebert AA, Henry M, J. Gassmueller, J.W. Fluhr, K.H. Nietsch, Korting HC, Krochmal L, Luger T, McKenzie A, Morgan JF, S. Schinzel, Savin RC, Seidenari S, Woodford R   +17 more
core   +1 more source

A Depolarizing Leak in Sodium Bicarbonate Cotransporter NBCe1 Causes Brain Edema

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives SLC4A4 encodes electrogenic sodium bicarbonate cotransporter NBCe1, prominently expressed in kidney and brain. Recessive loss‐of‐function variants in SLC4A4 cause proximal renal tubular acidosis, no brain edema. In the brain, NBCe1 is expressed by astrocytes, where it regulates pH and mediates astrocyte volume changes.
Quinty Bisseling, Mark D. Parker, Sven Kerst, Richard A. Pasternack, Jacob Tondreau, Marjolein Breur, Gemma M. van Rooijen‐van Leeuwen, Davide Tonduti, Ettore Salsano, Alejandra Darling, Joanna A. E. van Wijk, Susanna Törnroth‐Horsefield, Marianna Bugiani, Petra J. W. Pouwels, Quinten Waisfisz, Marjo S. van der Knaap, Rogier Min   +16 more
wiley   +1 more source

Cholesterol-embolization syndrome: current perspectives

Vascular Health and Risk Management, 2019
Abdullah OzkokDepartment of Internal Medicine and Nephrology, Memorial Şişli Hospital, Istanbul, TurkeyAbstract: Cholesterol-embolization syndrome (CES) is a multisystemic disease with various clinical manifestations.
Ozkok A
doaj  

Bone mineral density and fracture risk with long-term use of inhaled corticosteroids in patients with asthma: systematic review and meta-analysis [PDF]

, 2015
Objectives: We aimed to assess the association between long-term use of inhaled corticosteroids (ICS) and bone adverse effects in patients with asthma. Design: Systematic review and meta-analysis of fracture risk and changes in bone mineral density with ...
Agertoft, Allen, Bahceciler, British-Thoracic-Society/Scottish-Intercollegiate-Guidelines-Network, El, Ferguson, Harris, Higgins, Higgins, Ioannidis, Johannes, Jones, Kelly, Kemp, Law, Li, Loke, Loke, Maspero, National-Asthma-Education-and-Prevention-Program, Ricciardolo, Richy, Rossi, Roux, Schlienger, Sosa, The Childhood Asthma Management Program Research Group, Turpeinen, Van Staa, Vanfleteren, Weatherall, Wisniewski, Yanik   +32 more
core   +1 more source

Multiple Sclerosis Relapse Activity After Ozanimod Discontinuation in DAYBREAK Trial Participants

Annals of Clinical and Translational Neurology, EarlyView.
Multiple Sclerosis Relapse Activity After Ozanimod Discontinuation in DAYBREAK Trial Participants. ABSTRACT Objective Return of disease activity is expected when patients discontinue disease‐modifying therapy (DMT) for multiple sclerosis (MS). Some MS DMTs are associated with higher‐than‐expected disease activity (rebound) after discontinuation.
Ralf Gold, Krzysztof W. Selmaj, Regina Berkovich, Jeffrey A. Cohen, Giancarlo Comi, Eva K. Havrdová, James K. Sheffield, Hetal Desai, Chun‐Yen Cheng, Jon V. Riolo, Andrew Thorpe, Erik DeBoer, Bruce A. C. Cree   +12 more
wiley   +1 more source

Quantification of muscle strength and motor ability in patients with Duchenne muscular dystrophy on steroid therapy Quantificação da força muscular e habilidades motoras em pacientes com distrofia muscular de Duchenne em corticoterapia

Arquivos de Neuro-Psiquiatria, 2007
OBJECTIVE: An assessment protocol was applied to quantify and describe muscular strength and motor abilities of 32 patients with Duchenne muscular dystrophy (DMD), aged between 5 and 12 years on steroid therapy.
Samara Lamounier Santana Parreira, Maria Bernadete Dutra Resende, Marília Della Corte Peduto, Suely Kazue Nagahashi Marie, Mary Souza Carvalho, Umbertina Conti Reed   +5 more
doaj   +1 more source