Results 191 to 200 of about 67,094 (276)

Adipocyte-specific MC2R overexpression exerts minimal metabolic effects in mice. [PDF]

Lab Anim Res
Lim S, Evallo E, Kim DI, Park MJ.
europepmc   +1 more source

A₃ adenosine receptor regulates depression-like behaviors through astrocyte-nourished excitatory synapse formation. [PDF]

iScience
Li B, Zeng M, Liu J, Huang W, Pan D, Xiao C, Du J.   +6 more
europepmc   +1 more source

Confined spaces in space: Cerebral implications of chronic elevations of inspired carbon dioxide and implications for long‐duration space travel

Experimental Physiology, Volume 111, Issue 9, Page 3968-3982, 1 September 2026.
Abstract Cerebrovascular regulation is critically dependent upon the arterial partial pressure of carbon dioxide (PaCO2${P_{{\mathrm{aC}}{{\mathrm{O}}_{\mathrm{2}}}}}$), owing to its effect on cerebral blood flow, tissue PCO2${P_{{\mathrm{C}}{{\mathrm{O}}_{\mathrm{2}}}}}$, tissue proton concentration, cerebral metabolism and cognitive and neuronal ...
Jay M. J. R. Carr, Philip N. Ainslie, Trevor Day   +2 more
wiley   +1 more source

Thyroid antibody positivity in pregnancy is associated with altered reproductive hormone concentrations and placental growth in Lewis rats

The Journal of Physiology, Volume 604, Issue 17, Page 7464-7489, 1 September 2026.
Abstract figure legend Thyroid antibody positivity (TAb+) in pregnancy is associated with adverse pregnancy outcomes, but the mechanisms are unclear. This study developed a rodent model of TAb+ in pregnancy, induced prior to mating so that TAb+ exposure occurred throughout the pregnancy. TAb+ did not alter thyroid hormone concentrations and had minimal
Rebecca L. Brady, Nykola L. Kent, Anna G. Reid, Liana P. Paszkowski, Ashley S. Meakin, Dayna A. Zimmerman, Dinithi T. Mahaliyanage, Elliott S. Neal, Michael D. Wiese, Helle Bielefeldt‐Ohmann, Janna L. Morrison, James S. M. Cuffe   +11 more
wiley   +1 more source

Voluntary wheel running behavior is reduced by SARS-CoV-2 S1 administration and mitigates hypothalamic neuroinflammatory processes. [PDF]

Brain Behav Immun Health
Kelley T, Frank MG, Ball JB, Hopkins S, Nguyen TH, Thompson RS, Maier SF, Fleshner M.   +7 more
europepmc   +1 more source

Re‐evaluation of salt of aspartame‐acesulfame (E 962) as food additive

EFSA Journal, Volume 24, Issue 9, September 2026.
Abstract The present opinion deals with the re‐evaluation of salt of aspartame‐acesulfame (E 962) as a food additive. The Panel considered that upon ingestion, E 962 dissociates into aspartame and acesulfame ions which correspond to those of the authorised sweeteners aspartame (E 951) and acesulfame K (E 950). The Panel therefore assessed the safety of
EFSA Panel on Food Additives and Flavourings (FAF), Laurence Castle, Monica Andreassen, Gabriele Aquilina, Maria Lourdes Bastos, Polly Boon, Biagio Fallico, Rex FitzGerald, Maria Jose Frutos Fernandez, Bettina Grasl‐Kraupp, Ursula Gundert‐Remy, Rainer Gürtler, Eric Houdeau, Marcin Kurek, Henriqueta Louro, Patricia Morales, Sabina Passamonti, Ellen Bruzell, Cristina Fortes, Kevin James Chipman, Riccardo Crebelli, Peter Fürst, Jean‐Charles Leblanc, Evangelia Ntzani, Andrea Terron, Matthew Wright, Stefania Barmaz, Costanza Bonnici, Consuelo Civitella, Elena Mazzoli, Josef Daniel Rasinger, Ana Rincon, Camilla Smeraldi, Alexandra Tard, Federica Lodi   +34 more
wiley   +1 more source

Stress and HPA axis dysfunction impact diverse epilepsy outcomes including psychiatric comorbidities and SUDEP. [PDF]

Epilepsy Res
Joyal KG, Maguire JL.
europepmc   +1 more source

Nonlinearities and Switch‐Like Behavior in Gene Expression: From Genetics to Biochemistry and Back

The FASEB Journal, Volume 40, Issue 16, 31 August 2026.
Modest changes in transcription‐factor or chromatin‐regulator dosage can have disproportionate effects when gene‐regulatory systems operate near nonlinear thresholds. Sigmoidal input–output relationships, chromatin and cofactor recruitment, and changes in threshold position or response steepness provide molecular routes by which quantitative dosage ...
Reiner A. Veitia, James A. Birchler
wiley   +1 more source

Chronic stress unleashes an intratumor phage-fibroblast-B cell circuit to promote tumor growth. [PDF]

Cancer Cell
Bashir H, Sanidad KZ, Ravisankar P, Banks KM, Bose A, Yu S, McGrath JJC, Carrow HC, Kim TK, Troxell CA, Brown JA, Hart LR, Goc J, Egeblad M, Chaudhuri J, Kim HS, Wilson PC, Lyden DC, Matei IR, Inohara N, Sonnenberg GF, Zeng MY.   +21 more
europepmc   +1 more source

Zika Virus Inoculation During Pregnancy Impaired Maternal Care and Altered Prolactin and Corticosterone Levels in Rats. [PDF]

Dev Neurobiol
Gomes-da-Costa M, Souza Dos Santos A, Bohn ALL, Saturnino BCC, Aguiar GB, Jacobs GB, Danilevicz CK, Varela APM, Teixeira TF, Roehe PM, Pereira LO.   +10 more
europepmc   +1 more source