ABSTRACT Objective This review critically examines psilocybin, with particular emphasis on its pharmacokinetics and pharmacodynamics, including its serotonergic, neuroplastic, and anti‐inflammatory mechanisms. It integrates historical context, preclinical and clinical evidence, and evaluates emerging therapeutic potential, safety, microdosing practices,
José Norberto Vásquez‐Bonilla
wiley +1 more source
Effect of glucocorticoid production by the enteric nervous system on neuronal connectivity is blocked during inflammation in a GR-dependent pathway. [PDF]
Blin J +9 more
europepmc +1 more source
Bile acid metabolism and signaling in human and animal health: A One Health perspective
Bile acids maintain host homeostasis through enterohepatic circulation, microbial transformation, and bile acid receptor signaling, thereby regulating glucose and lipid metabolism, intestinal barrier integrity, and immunity. These effects support human disease intervention and health‐oriented animal production, reducing drug dependence and residue ...
Lei Li +7 more
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Continued Advancement in Understanding of Corticosterone in Psittacines. [PDF]
Brunner TJ, Penticoff HB, Tully TN.
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Abstract In recent years, the clinical treatment and symptom management of neurological disorders have faced significant challenges due to the high complexity of the nervous system's structure and function. Against this backdrop, physical stimulation techniques have emerged as a vital complementary approach to traditional pharmacological treatments and
Wanying Li, Liqun Chen
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Correction: Met-enkephalin modulates the stress responses of plasma concentrations of corticosterone, delta opioid receptor binding, pro-enkephalin expression, and processing in chickens. [PDF]
Pierzchała-Koziec K +2 more
europepmc +1 more source
Chronic stress modifies the effect of oxycodone conditioned place preference (Oxy CPP) on corticotropin releasing factor 1 (CRFR1) subcellular distributions in hippocampal subregions. These stress‐ and oxycodone‐induced changes in CRFR1 density may influence sex differences in hippocampal learning and memory processes both at baseline and following Oxy
Dana N. Silberstein +7 more
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Supplementation with Lactobacillus plantarum alone or combined with Saccharomyces cerevisiae improved laying performance, egg quality, immune response and caecal microbial balance by increasing beneficial lactic acid bacteria and reducing coliforms, demonstrating probiotics as a safe and sustainable alternative to antibiotic growth promoters in ...
Md. Jahangir Alam +5 more
wiley +1 more source
Heat and cold stresses exert disparate effects on expression of proenkephalin, and concentrations of Met-enkephalin in the hypothalamus, pituitary and adrenal glands, plasma concentrations Met-enkephalin, Leu-enkephalin, β-endorphin and corticosterone and opioid receptor binding in chickens. [PDF]
Scanes CG, Pierzchała-Koziec K.
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