Results 151 to 160 of about 96,764 (277)
The Predictive Accuracy of Methods Commonly Used for Evaluating Animal Distress
Predictive accuracy of body weight change, distress score, burrowing, and nesting behavior across multiple intervention phases. ABSTRACT Accurate distress assessment is essential for ensuring animal welfare and scientific validity. Although behavioral and physiological indicators are commonly used, their predictive value across disease models and ...
Emily Leitner +6 more
wiley +1 more source
Stress, stress systems, and Alzheimer's disease
Abstract Stress is increasingly recognized as an important, modifiable factor for Alzheimer's disease (AD), yet its roles in initiation, progression, and outcomes remain incompletely elucidated. Epidemiologic studies link chronic stress, early‐life adversity, and trauma to increased AD risk, while experimental models have uncovered mechanisms by which ...
Stephanie G. Eberly +5 more
wiley +1 more source
ABSTRACT Steroids are critical for numerous physiological processes; disruption in their metabolism is associated with numerous endocrine disorders. Steroid quantification is essential to improve the understanding and diagnosis of these pathologies. Historically, urinary steroid profiling has been performed using low‐throughput gas chromatography mass ...
Joshua T. Bain +4 more
wiley +1 more source
Roe deer in Kiasar National Park and Wildlife Refuge, Iran; Photo by Hamed Tizrooyan. This study examined how seasonal, climatic, topographic, habitat, and sex variables influence fecal cortisol, testosterone, and progesterone metabolite concentrations in roe deer populations within Iran's Kiasar National Park and Wildlife Refuge through fecal sample ...
Seyed Mehdi Amininasab +2 more
wiley +1 more source
The Role of Endothelin‐1 in Autoimmune Diseases: Mechanistic Insights and Therapeutic Targets
The Role of Endothelin‐1 in Autoimmune Diseases. NF‐κB: nuclear factor kappa‐B; MAPK: mitogen‐activated protein kinase; PI3K: phosphoinositide 3‐kinase; ROS: reactive oxygen species; CTGF: connective tissue growth factor; TGF‐β: transforming growth factor‐β.
Xun Gong +5 more
wiley +1 more source
MyoRep: A Novel Reporter System to Detect Early Muscle Atrophy In Vitro and In Vivo
ABSTRACT Background Muscle atrophy occurs during physiological (i.e., fasting) and pathological conditions (i.e., cancer) and anticipates death. Since not all patients will undergo muscle wasting, it would be highly useful to identify them soon to intervene early.
Andrea D. Re Cecconi +11 more
wiley +1 more source
ABSTRACT Steroid‐mediated maternal effects are well‐studied as a source of phenotypic variation. In bird eggs, the yolk contains various steroids that can influence embryonic development. However, one complicating factor in understanding how yolk steroids affect development is that the embryo metabolizes yolk steroids to regulate exposure.
Ryan T. Paitz +4 more
wiley +1 more source
This review highlights nanoencapsulation as a powerful strategy to improve the stability, solubility, and bioavailability of essential oils. It surveys key EO‐producing plant families, major bioactive constituents, and therapeutic properties, alongside high‐ and low‐energy nanoformulation methods. Applications across pharmaceutical, cosmetic, food, and
Mateusz Guz +3 more
wiley +1 more source
Research note: A longitudinal evaluation of feather corticosterone in two broiler genotypes in a pasture-based system. [PDF]
Aderibigbe AS.
europepmc +1 more source

