Results 131 to 140 of about 69,134 (261)

Physiological media and oxygen levels modulate cancer hallmarks in cultured breast cancer cells

The FEBS Journal, EarlyView.
MCF7 breast cancer cells were cultured in standard conditions (18% O2 and DMEM) and physiological conditions (5% O2 and Plasmax, a medium modeled after the human plasma metabolome). A combined transcriptomic and proteomic approach was used to identify gene expression signatures at the mRNA and protein levels upstream of functional enrichment analyses ...
Jacob E. Wiebe, Ricardo Alva, Fereshteh Moradi, Sarah Alderman, Ping Liang, Jeffrey A. Stuart   +5 more
wiley   +1 more source

Adrenal hormones in the maintenance of glucose homeostasis during prolonged fasting in male glucagon‐deficient mice

Journal of Diabetes Investigation, EarlyView.
Compensatory corticosterone‐mediated lipolysis and hepatic gluconeogenesis (via amino acids and glycerol) prevent hypoglycemia in GCGKO mice during prolonged fasting. ABSTRACT Aims/Introduction Glucagon is a key regulator of fasting glucose homeostasis, but the contribution of adrenal hormones during prolonged fasting remains unclear.
Sayumi Kanie, Koki Nishida, Yusuke Seino, Shihomi Hidaka, Shinji Ueno, Hiroaki Sumioki, Eisuke Tomatsu, Takuya Haraguchi, Naoya Murao, Haruki Fujisawa, Takeshi Takayanagi, Yoshihisa Sugimura, Yoshitaka Hayashi, Atsushi Suzuki   +13 more
wiley   +1 more source

Expression of corticoid‐regulatory genes in the gills of Atlantic salmon (Salmo salar) parr and smolt and during salinity acclimation

Journal of Fish Biology, EarlyView.
Abstract In teleost fishes, cortisol is the major corticoid and has both glucocorticoid and mineralocorticoid actions. However, how fish tissues discriminate between these distinct corticosteroid actions is unclear. In mammals, the major factors responsible for intracellular corticosteroid regulation are glucocorticoid receptors (grs) and the ...
Makoto Kusakabe, Takashi Yada, Graham Young, Amy M. Regish, Stephen D. McCormick   +4 more
wiley   +1 more source

The Protective Effects of Polygala tenuifolia and Tenuifolin on Corticosterone-Evoked Ferroptosis, Oxidative Stress, and Neuroinflammation: Insights from Molecular Dynamics Simulations and In Vitro Experiments

Foods
Excessive stress is a well-established contributor to neurological damage, insomnia, and depression, imposing a significant burden on individuals and society. This underscores the urgent need for effective stress-relief strategies.
Chaoyi Xue, Zhiyong He, Maomao Zeng, Zhaojun Wang, Qiuming Chen, Fang Qin, Mingmin Chen, Hui Ye, Jie Chen   +8 more
doaj   +1 more source

Corticosterone Concentrations in the Mouse [PDF]

Science, 1978
D H, Spackman, V, Riley
openaire   +2 more sources

Corticosterone inhibits endothelial cell migration.

, 2012
Endothelial cells (2.0×106) were plated in 60 mm2 plates coated with 1.5% gelatin and treated with 600 nM corticosterone for 48 hours. Cells were pretreated with 5 µg/ml Mitomycin C for 2 hours prior to removing cells from half of the dish using a rubber
Sammy T. K. Liu (131272), Michael C. Riddell (131295), Eric A. Shikatani (131260), Andrei Szigiato (131286), Anna Krylova (131281), Anastassia Trifonova (131263), Emilie Roudier (131276), Jacqueline Beaudry (131290), Erin R. Mandel (131267), Tara L. Haas (131300)   +9 more
core   +1 more source

Of mice and men—The emerging oral–gut–brain axis of health and disease

Periodontology 2000, EarlyView.
Abstract Objectives Oral health's inextricable links to systemic health are highlighted by the emerging oral–gut–brain axis and other well‐known axes. There is growing evidence of a complex oral–gut–brain axis linking mouth and gut microbiomes with the central nervous system.
Yvonne L. Hernandez‐Kapila, Daniel J. Weisenberger   +1 more
wiley   +1 more source

Ovariectomy, but not moderate intermittent hypoxia, promotes respiratory instability and risk of obesity in adult female rats

Experimental Physiology, EarlyView.
Abstract Sleep apnoea (SA) is a prevalent and complex respiratory disorder associated with recurrent interruptions of air flow during sleep. SA causes sleep fragmentation and intermittent hypoxia which leads to numerous negative health consequences.
Marianne Gagnon, Stéphanie Fournier, François Marcouiller, Natalie J. Michael, Vincent Joseph, Richard Kinkead   +5 more
wiley   +1 more source

Dear Influencers: Don't Disturb Amphibians and Reptiles for More Followers

Animal Conservation, EarlyView.
José Guerrero‐Casado, Ricardo Reques
wiley   +1 more source

Context‐dependent effects of whole‐body vibration on reproductive function and penile tissue integrity in sedentary male rats

Experimental Physiology, EarlyView.
Abstract Sedentary behaviour is increasingly recognized as a risk factor for systemic disorders; however, its effects on male reproductive health and penile tissue integrity remain insufficiently understood. Furthermore, the therapeutic role of whole‐body vibration (WBV) has not been investigated. This study evaluated the effects of sedentary behaviour
Mujdat Ayva, Senay Akin, Irem Gungor Orhan, Neslihan Coskun Akcay, Berkay Ozerklig, Kemal Kosemehmetoglu, Mesut Altan, Haydar A. Demirel, Fazil Tuncay Aki   +8 more
wiley   +1 more source