Results 121 to 130 of about 43,220 (248)

Local Circadian Clocks Are Desynchronized From the Central Circadian Pacemaker in a Mouse Model of Inflammatory Arthritis

open access: yesACR Open Rheumatology, Volume 8, Issue 7, July 2026.
Objective Rheumatoid arthritis (RA) is a chronic autoimmune disease affecting joints marked by daily and intermittent surges in inflammatory cytokine levels that result in “flares” of disease activity. Because circadian proteins regulate inflammatory responses in arthritis, continuous behavioral‐ and tissue‐level monitoring may clarify therapeutic ...
Lance A. Riley   +6 more
wiley   +1 more source

Paternal Circadian Disruption Impairs Offspring Cognition via Sperm microRNAs

open access: yesAdvanced Science, Volume 13, Issue 37, 3 July 2026.
Paternal circadian disruption remodels the sperm small RNA payload, elevating miR‐92a‐3p/miR‐25‐3p levels and perturbing early embryonic gene regulatory programs. Microinjection experiments and single‐embryo transcriptomics reveal sex‐specific developmental vulnerabilities, ultimately impairing offspring hippocampal synaptic plasticity and cognition ...
Kexin Zou   +22 more
wiley   +1 more source

Comparative analysis of physiological, biochemical and immunological responses to heat stress in hybrid and purebred ducks in tropical environments. [PDF]

open access: yesVet Anim Sci
Hemayet MA   +9 more
europepmc   +1 more source

Paternal Caffeine Exposure Programs Offspring Stress Vulnerability via Sperm Dlk1‐Dio3 Imprinting‐Directed Remodeling of a Novel Neural Circuit

open access: yesAdvanced Science, Volume 13, Issue 40, 17 July 2026.
The study elucidates that paternal preconception stress can drive offspring hyperresponsivity of the stress system via hypomethylation of a specific DNA region in sperm. This key link is confirmed in a cohort of prospective fathers: the epigenetic alteration is associated with elevated stress hormone levels.
Mengxi Lu   +10 more
wiley   +1 more source

Interdigitale Aptamer‐Sensoren mit komplementären Messkanälen zur schnellen Detektion kleiner Moleküle in Biofluiden

open access: yesAngewandte Chemie, Volume 138, Issue 27, 1 July 2026.
Ein elektrochemischer Aptamer‐Sensorchip nutzt Interdigitalelektroden mit selektiver Monoschicht‐Funktionalisierung, um Dopamin und Cortisol mittels robuster komplementärer „Signal‐Off/On“‐Antworten zu detektieren. Diese Dual‐Channel‐Signalumwandlung ermöglicht eine schnelle Detektion innerhalb von 5–30 min bei geringen Probenvolumina in künstlicher ...
Senyao Wang   +12 more
wiley   +1 more source

Behavioral Convergence with Physiological Divergence: Sex Differences in Hormones but Not Social Behavior in Beagle Dogs. [PDF]

open access: yesAnimals (Basel)
Xiao YH   +10 more
europepmc   +1 more source

Dual‐Channel Interdigitated Aptamer‐Based Sensors for Rapid Small‐Molecule Detection in Biofluids

open access: yesAngewandte Chemie International Edition, Volume 65, Issue 27, 1 July 2026.
An electrochemical aptamer sensing chip employs dual interdigitated electrodes and selective self‐assembled monolayer removal to convert small‐molecule recognition into robust “signal‐off/on” responses. This dual‐channel signal conversion minimizes background noise and accelerates probe diffusion, enabling rapid (as fast as 5–30 min), low‐volume ...
Senyao Wang   +12 more
wiley   +1 more source

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