Objective Rheumatoid arthritis (RA) is a chronic autoimmune disease affecting joints marked by daily and intermittent surges in inflammatory cytokine levels that result in “flares” of disease activity. Because circadian proteins regulate inflammatory responses in arthritis, continuous behavioral‐ and tissue‐level monitoring may clarify therapeutic ...
Lance A. Riley +6 more
wiley +1 more source
Environmental Enrichment Attenuates Fentanyl-Seeking Behavior and Protects against Stress-Induced Reinstatement in Both Male and Female Rats. [PDF]
Higginbotham JA +5 more
europepmc +1 more source
Paternal Circadian Disruption Impairs Offspring Cognition via Sperm microRNAs
Paternal circadian disruption remodels the sperm small RNA payload, elevating miR‐92a‐3p/miR‐25‐3p levels and perturbing early embryonic gene regulatory programs. Microinjection experiments and single‐embryo transcriptomics reveal sex‐specific developmental vulnerabilities, ultimately impairing offspring hippocampal synaptic plasticity and cognition ...
Kexin Zou +22 more
wiley +1 more source
Comparative analysis of physiological, biochemical and immunological responses to heat stress in hybrid and purebred ducks in tropical environments. [PDF]
Hemayet MA +9 more
europepmc +1 more source
The study elucidates that paternal preconception stress can drive offspring hyperresponsivity of the stress system via hypomethylation of a specific DNA region in sperm. This key link is confirmed in a cohort of prospective fathers: the epigenetic alteration is associated with elevated stress hormone levels.
Mengxi Lu +10 more
wiley +1 more source
Integrative analysis of gut microbiota and plasma metabolites reveals mechanisms underlying aggressive behavior in chronically stressed broiler chickens. [PDF]
Wu X +5 more
europepmc +1 more source
Ein elektrochemischer Aptamer‐Sensorchip nutzt Interdigitalelektroden mit selektiver Monoschicht‐Funktionalisierung, um Dopamin und Cortisol mittels robuster komplementärer „Signal‐Off/On“‐Antworten zu detektieren. Diese Dual‐Channel‐Signalumwandlung ermöglicht eine schnelle Detektion innerhalb von 5–30 min bei geringen Probenvolumina in künstlicher ...
Senyao Wang +12 more
wiley +1 more source
Behavioral Convergence with Physiological Divergence: Sex Differences in Hormones but Not Social Behavior in Beagle Dogs. [PDF]
Xiao YH +10 more
europepmc +1 more source
Dual‐Channel Interdigitated Aptamer‐Based Sensors for Rapid Small‐Molecule Detection in Biofluids
An electrochemical aptamer sensing chip employs dual interdigitated electrodes and selective self‐assembled monolayer removal to convert small‐molecule recognition into robust “signal‐off/on” responses. This dual‐channel signal conversion minimizes background noise and accelerates probe diffusion, enabling rapid (as fast as 5–30 min), low‐volume ...
Senyao Wang +12 more
wiley +1 more source
Intraperitoneal Injection of Cisplatin Induces Nausea-Like Responses without Vomiting in Chicks (<i>Gallus gallus domesticus</i>). [PDF]
Nakamura K +3 more
europepmc +1 more source

