Results 101 to 110 of about 96,764 (277)

Complement C3 mediates adolescent social isolation‐induced hippocampal synaptic deficits and sex‐specific emotional dysfunction

Interdisciplinary Medicine, EarlyView.
Adolescent social isolation disrupts hippocampal function and exacerbates emotional symptoms, with sex‐specific patterns, as shown by human studies. In mice, social isolation decreased hippocampal synaptic density and calcium signaling, upregulated complement proteins, and activated complement‐mediated microglial synaptic phagocytosis.
Yuwan Qi, Siying Weng, Qiao Yin, Mengqi Li, Liang Shen, Enyou Qiao, Lu Gao, Yihan Wang, Yuxuan Li, Weifeng Luo, Qilin Zhang, Jing Wang, Jianfeng Feng, Qifei Cong   +13 more
wiley   +1 more source

Resíduos de aflatoxina B1 em fígado de codornas japonesas (Coturnix japonica) expostas a alimentos contaminados e à corticosterona exógena [PDF]

, 2013
The combined effect of aflatoxin B1 (AFB1 ) exposition and stress induced by corticosterone (CORT) upon the residual aflatoxin levels in livers of Japanese quail was examined.
Chiacchiera, Stella Maris, Dalcero, Ana Maria, Magnoli, Alejandra Paola, Marin, Raul Hector, Rosa, Carlos Alberto da Rocha   +4 more
core   +1 more source

Effects of environmental enrichment on behavioral responses to novelty, learning, and memory, and the circadian rhythm in cortisol in growing pigs [PDF]

, 2000
Previously we showed that pigs reared in an enriched environment had higher baseline salivary cortisol concentrations during the light period than pigs reared under barren conditions.
Blokhuis, Harry J.,, Burgwal, Johan A. van de,, Jong, Ingrid C. de,, Koolhaas, Jaap M.,, Korte, S. Mechiel,, Lambooij, Elbert,, Prelle, Ina T.,   +6 more
core   +1 more source

Corticosterone - an anxiogenic or an anxiolytic agent?

Journal of Pharmacy and Pharmacology, 1979
Abstract Corticosterone (3–12 mg kg−1, i.p., giving rise to plasma corticosterone concentrations from 26.7 to 89.0 μg/100 ml) failed to have a significant anxiogenic action. Instead, corticosterone (3 mg kg−1) had a significant anxiolytic effect in the social interaction test of anxiety.
S E, File, S V, Vellucci, S, Wendlandt
openaire   +2 more sources

Corticosterone and Mitochondrial Efficiency Are Associated With Changes in DNA Oxidative Damage During an Acute Stress Response in Leach's Storm‐Petrels (Hydrobates leucorhous)

Journal of Experimental Zoology Part A: Ecological and Integrative Physiology, EarlyView.
ABSTRACT The ability of organisms to effectively respond to challenges is critical for survival. We investigated how an acute stressor affected corticosterone, mitochondrial function, and DNA oxidative damage in a wild population of Leach's storm‐petrels (Hydrobates leucorhous).
Kayla E. Lichtner, Jack K. Dziubek, Nicole A. Joseph, Sarah E. Chapman, Tori J. Chace, Dongxiao Sun, Zachary T. Bitzer, Antoine Stier, Robert A. Mauck, Patricia L. Jones, Mark F. Haussmann   +10 more
wiley   +1 more source

Home Cage Compared with Induction Chamber for Euthanasia of Laboratory Rats [PDF]

, 2018
This study compared behavioral and physiologic changes in Sprague-Dawley and Brown Norway rats that were euthanizedby using a 30% volume displacement rate of CO2 in either their home cage or an induction chamber; rats euthanized in thehome cage were ...
Hickman, Debra L.
core   +1 more source

Disentangling Temporal and Environmental Effects on Hematological Values in Prairie Rattlesnakes (Crotalus viridis)

Journal of Experimental Zoology Part A: Ecological and Integrative Physiology, EarlyView.
ABSTRACT Hematologic assessment is a common clinical tool used to characterize both individual and population health. In ectothermic organisms, the hematologic response is influenced by external factors such as temperature and season, especially in temperate species. Yet, specific environmental effects have received little direct attention.
Ethan J. Kessler, Sarah J. Baker, Ellen Haynes, Amy N. Schnelle, Matthew C. Allender   +4 more
wiley   +1 more source

Steroid profiling in male wobbler mouse, a model of Amyotrophic Lateral Sclerosis [PDF]

, 2016
The Wobbler mouse is an animal model for human motoneuron diseases, especially amyotrophic lateral sclerosis (ALS), used in the investigation of both pathology and therapeutic treatment.
Aprahamian, Fanny, Cambourg, Annie, de Nicola, Alejandro Federico, Di Giorgio, Noelia Paula, Gonzalez Deniselle, Maria Claudia, Guennoun, Rachida, Liere, Philippe, Meyer, Maria, Pianos, Antoine, Schumacher, Michael   +9 more
core   +1 more source

From regulatory mechanisms to cutting‐edge applications: Research progress of ultrasound, electrical, magnetic, and optical stimulation in neural modulation

Journal of Intelligent Medicine, EarlyView.
Abstract In recent years, the clinical treatment and symptom management of neurological disorders have faced significant challenges due to the high complexity of the nervous system's structure and function. Against this backdrop, physical stimulation techniques have emerged as a vital complementary approach to traditional pharmacological treatments and
Wanying Li, Liqun Chen
wiley   +1 more source

Indomethacin-antihistamine combination for gastric ulceration control [PDF]

, 1981
An anti-inflammatory and analgesic composition containing indomethacin and an H sub 1 or an H sub 2 histamine receptor antagonist in an amount sufficient to reduce gastric distress caused by the indomethacin is described.
Brown, P. A., Danellis, J. V.
core   +1 more source