Results 31 to 40 of about 134,745 (361)
Circadian and Ultradian Rhythms of Free Glucocorticoid Hormone Are Highly Synchronized between the Blood, the Subcutaneous Tissue, and the Brain [PDF]
, 2012 Total glucocorticoid hormone levels in plasma of various species, including humans, follow a circadian rhythm that is made up from an underlying series of hormone pulses. In blood most of the glucocorticoid is bound to corticosteroid-binding globulin and
Droste, Susanne K +4 more
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Physiological Reports, 2016 Mice are used extensively in physiological research. Automated home‐cage systems have been developed to study single‐housed animals. Increased stress by different housing conditions might affect greatly the results when investigating metabolic responses.
Remi Kamakura +4 more
semanticscholar +1 more source
The Comparison of the Effects of Acute Swimming Stress on Plasma Corticosterone and Leptin Concentration in Male and Female Rats [PDF]
Acta Medica Iranica, 2011 The aim of this study was to investigate the effect of acute swimming stress on plasma corticosterone and leptin levels in female and male rats. Thirty- seven adult male (n=20) and female (n=20) Sprague Dawley rats (200-250 g weight) were used.
Parvin Zareian +2 more
doaj +1 more source
Corticosterone Regulates Both Naturally Occurring and Cocaine‐Induced Dopamine Signaling by Selectively Decreasing Dopamine Uptake [PDF]
, 2017 Stressful and aversive events promote maladaptive reward‐seeking behaviors such as drug addiction by acting, in part, on the mesolimbic dopamine system. Using animal models, data from our laboratory and others show that stress and cocaine can interact to
Baker, David A. +9 more
core +2 more sources
International Journal of Endocrinology, 2013 Endogenous glucocorticoids (GCs) have both stimulatory and suppressive effects on immune cells depending on the concentration. However, the mechanisms underlying the stimulatory effects of GCs remain elusive.
He-Jiang Zhong +4 more
doaj +1 more source
A physiological glucocorticoid rhythm is an important regulator of brown adipose tissue function
Molecular Metabolism, 2021 Objective: Brown adipose tissue (BAT) displays a strong circadian rhythm in metabolic activity, but it is unclear how this rhythm is regulated. As circulating levels of corticosterone coincide with the rhythm of triglyceride-derived fatty acid (FA ...
Jan Kroon +19 more
doaj
Molecules, 2016 Chronic glucocorticoid exposure is known to cause depression and metabolic disorders. It is critical to improve abnormal metabolic status as well as depressive-like behaviors in patients with long-term glucocorticoid therapy.
Yu-Cheng Li +5 more
doaj +1 more source
Animals, 2020 Assessment of animal welfare can include analysis of physiological parameters, as well as behavior and health. Levels of adrenocortical hormones such as cortisol (and corticosterone in chickens) have been relied on as indicators of stress.
Malcolm P. Caulfield, Matthew P. Padula
doaj +1 more source
Effect of vasopressin 1b receptor blockade on the hypothalamic-pituitary-adrenal response of chronically stressed rats to a heterotypic stressor [PDF]
, 2009 Exposure to chronic restraint (CR) modifies the hypothalamic–pituitary–adrenal (HPA) axis response to subsequent acute stressors with adaptation of the response to a homotypic and sensitization of the response to a heterotypic stressor. Since vasopressin
Craighead, Mark +5 more
core +1 more source
Frontiers in Endocrinology, 2022 Synthetic glucocorticoids are clinically used to treat auto-immune and inflammatory disease. Despite the high efficacy, glucocorticoid treatments causes side effects such as obesity and insulin resistance in many patients.
Lisa L. Koorneef +19 more
doaj +1 more source