Results 51 to 60 of about 43,220 (248)

Epigallocatechin-3-gallate confers protection against corticosterone-induced neuron injuries via restoring extracellular signal-regulated kinase 1/2 and phosphatidylinositol-3 kinase/protein kinase B signaling pathways.

PLoS ONE, 2018
Extensive studies suggested epigallocatechin-3-gallate (EGCG) has significant neuroprotection against multiple central neural injuries, but the underlying mechanisms still remain poorly elucidated.
Xiaoling Zhao, Renjia Li, Hui Jin, Haimin Jin, Yonghui Wang, Wanqi Zhang, Haichao Wang, Weiqiang Chen   +7 more
doaj   +1 more source

A Radioimmunoassay for Human Plasma Corticosterone

Endocrinologia Japonica, 1976
A radioimmunoassay for human plasma corticosterone has been developed. Antiserum against corticosterone was produced in rabbits immunized with corticosterone-21-hemisuccinate conjugated to bovine serum albumin. The antiserum cross-reacted with progesterone, DOC and dehydrocorticosterone more than 20%. After the extraction with ether, and the separation
NISHIDA, SEIKOH, MATSUMURA, SHIGEICHI, HORINO, MASAHARU, OYAMA, HIDEKI, TENKU, ATSUKO   +4 more
openaire   +2 more sources

How developmental stressors affect mitochondrial respiratory function: a systematic review and meta‐analysis

Biological Reviews, EarlyView.
ABSTRACT The environmental conditions organisms experience during early development can have powerful and sustained effects on morphology, physiology, behaviour, and performance. Such developmental effects can influence reproductive success, survival, and life‐history strategies and can be transmitted across generations (i.e.
Ondi L. Crino, Christopher R. Friesen, Geoffrey E. Hill, Dalton C. Leibold, Pablo Recio, Karine Salin, Kristoffer H. Wild, Daniel W.A. Noble   +7 more
wiley   +1 more source

3,5,6,7,8,3′,4′-Heptamethoxyflavone, a Citrus Flavonoid, Ameliorates Corticosterone-Induced Depression-like Behavior and Restores Brain-Derived Neurotrophic Factor Expression, Neurogenesis, and Neuroplasticity in the Hippocampus

Molecules, 2016
We previously reported that the citrus flavonoid 3,5,6,7,8,3′,4′-heptamethoxyflavone (HMF) increased the expression of brain-derived neurotrophic factor (BDNF) in the hippocampus of a transient global ischemia mouse model.
Atsushi Sawamoto, Satoshi Okuyama, Kana Yamamoto, Yoshiaki Amakura, Morio Yoshimura, Mitsunari Nakajima, Yoshiko Furukawa   +6 more
doaj   +1 more source

Corticosterone in Lymphoma-Bearing Rats.

Experimental Biology and Medicine, 1963
SummaryCorticosterone in plasma and urine was determined by spectrofluorometry in sulfuric acid and by direct spectrophotometry in ethanol. Plasma levels and urinary excretion of corticosterone were elevated in rats with subcutaneous lymphomas. The high plasma concentration of corticosterone in these rats may help to explain the reduction in splenic ...
L, PERIC-GOLIA, R S, JONES
openaire   +2 more sources

Perinatal Changes in Liver Corticosterone, Serum Insulain and Plasma Glucagon and Corticosterone in the Rat [PDF]

European Journal of Biochemistry, 1978
This report describes some hormonal changes occuring in the rat during the last 3 days of gestation and the first 6 h after surgical deliversy on days 20–22uu ofgestation. In the foetus, the concentration of glucagon increased 2‐fold and that of insulin decreaed from 4.7 to 3.5 ng/ml between days 21 and 22. Consequently the insulin/glucagon molar ratio
P N, Di Marco, A V, Ghisalberti, C E, Martin, I T, Oliver   +3 more
openaire   +2 more sources

Metabolic abnormalities and reprogramming in cats with naturally occurring hypertrophic cardiomyopathy

ESC Heart Failure, Volume 12, Issue 2, Page 1256-1270, April 2025.
Abstract Background and aims The heart is a metabolic organ rich in mitochondria. The failing heart reprograms to utilize different energy substrates, which increase its oxygen consumption. These adaptive changes contribute to increased oxidative stress.
Qinghong Li, Max Homilius, Erin Achilles, Laura K. Massey, Victoria Convey, Åsa Ohlsson, Ingrid Ljungvall, Jens Häggström, Brittany Vester Boler, Pascal Steiner, Sharlene Day, Calum A. MacRae, Mark A. Oyama   +12 more
wiley   +1 more source

Sustained corticosterone rise in the prefrontal cortex is a key factor for chronic stress-induced working memory deficits in mice

Neurobiology of Stress, 2019
Exposure to prolonged, unpredictable stress leads to glucocorticoids-mediated long-lasting neuroendocrine abnormalities associated with emotional and cognitive impairments.
Gaelle Dominguez, Nadia Henkous, Thomas Prevot, Vincent David, Jean-Louis Guillou, Catherine Belzung, Nicole Mons, Daniel Béracochéa   +7 more
doaj   +1 more source

Corticosteroid-binding-globulin (CBG)-deficient mice show high pY216-GSK3β and phosphorylated-Tau levels in the hippocampus.

PLoS ONE, 2021
Corticosteroid-binding globulin (CBG) is the specific carrier of circulating glucocorticoids, but evidence suggests that it also plays an active role in modulating tissue glucocorticoid activity. CBG polymorphisms affecting its expression or affinity for
José Gulfo, Joana Pérez de San Román, Angelo Ledda, Felix Junyent, María J Ramírez, Francisco J Gil-Bea, Montserrat Esteve, Mar Grasa   +7 more
doaj   +1 more source

Measurement of corticosterone in mice: a protocol for a mapping review [PDF]

Laboratory Animals, 2019
Severity assessment for experiments conducted with laboratory animals is still based mainly on subjective evaluations; evidence-based methods are scarce. Objective measures, amongst which determination of the concentrations of stress hormones, can be used to aid severity assessment.
Leenaars, Cathalijn H C, van der Mierden, Stevie, Durst, Mattea, Goerlich-Jansson, Vivian C, Ripoli, Florenza Lüder, Keubler, Lydia M, Talbot, Steven R, Boyle, Erin, Habedank, Anne, Jirkof, Paulin, Lewejohann, Lars, Gass, Peter, Tolba, René, Bleich, André   +13 more
openaire   +6 more sources