Results 41 to 50 of about 138,058 (298)

Validating the underpinnings of water corticosterone measurement for aquatic amphibians [version 1; peer review: 2 approved]

F1000Research
Background Good animal welfare is important ethically but also to ensure animals provide valid scientific models. Despite thousands of amphibians in research laboratories there is minimal quantitative evidence pertaining to their management and welfare ...
Charlotte A Hosie, Robert Coleman, Christopher J Emmans, Andrew M Holmes, Tessa E Smith   +4 more
doaj   +1 more source

Effect of the glucocorticoid receptor antagonist Org 34850 on fast and delayed feedback of corticosterone release [PDF]

, 2007
We investigated the effect of the glucocorticoid receptor (GR) antagonist Org 34850 on fast and delayed inhibition of corticosterone secretion in response to the synthetic glucocorticoid methylprednisolone (MPL).
Craighead, Mark, Grassie, Morag, Harrison, Louse R., Lightman, Stafford L., MacSweeney, Cliona P., Spiga, Francesca, Thomson, Fiona .J., Wood, Susan A.   +7 more
core   +1 more source

Bioconversion of Corticosterone into Corticosterone-Glucoside by Glucosyltransferase

Molecules, 2018
Glucosylation of the 21-hydroxyl group of glucocorticoid changes its solubility into hydrophilicity from hydrophobicity and, as with glucocorticoid glucuronides as a moving object in vivo, it is conceivable that it exhibits the same behavior.
Tokutaro Yamaguchi, Joo-Ho Lee, A-Rang Lim, Joon-Soo Sim, Eun-Ji Yu, Tae-Jin Oh   +5 more
doaj   +1 more source

Dexamethasone-associated metabolic effects in male mice are partially caused by depletion of endogenous corticosterone

Frontiers in Endocrinology, 2022
Synthetic glucocorticoids are clinically used to treat auto-immune and inflammatory disease. Despite the high efficacy, glucocorticoid treatments causes side effects such as obesity and insulin resistance in many patients.
Lisa L. Koorneef, Lisa L. Koorneef, Merel van der Meulen, Merel van der Meulen, Sander Kooijman, Sander Kooijman, Elena Sánchez-López, Jari F. Scheerstra, Jari F. Scheerstra, Maaike C. Voorhoeve, Maaike C. Voorhoeve, Ajith N. Nadamuni Ramesh, Ajith N. Nadamuni Ramesh, Patrick C. N. Rensen, Patrick C. N. Rensen, Martin Giera, Jan Kroon, Jan Kroon, Onno C. Meijer, Onno C. Meijer   +19 more
doaj   +1 more source

Comparing plasma and faecal measures of steroid hormones in Adelie penguins Pygoscelis adeliae [PDF]

, 2010
Physiological measurements of both stress and sex hormones are often used to estimate the consequences of natural or human-induced change in ecological studies of various animals.
Banks, Jonathan C., Bell, Dudley G., Bright, A., Carey, P.W., Chandler, J., Hudson, Q.J., Ingram, J.R., Ling, Nicholas, Lyall, K., Morgan, Dai K.J., Möstl, E., Nakagawa, Shinichi, Ninnes, Calum Edward, Stevens, Mark I., Waas, Joseph R., Wallace, J.   +15 more
core   +2 more sources

Corticosterone selectively decreases humoral immunity in female eiders during incubation

, 2007
Immunity is hypothesized to share limited resources with other physiological functions and this may partly account for the fitness costs of reproduction.
Bourgeon, Sophie, Raclot, Thierry
core   +1 more source

Repeated stressors in adulthood increase the rate of biological ageing [PDF]

, 2015
Background Individuals of the same age can differ substantially in the degree to which they have accumulated tissue damage, akin to bodily wear and tear, from past experiences.
Adelman, James S., Costantini, David, Greives, Timothy J., Hau, Michaela, Haussmann, Mark F., Matlack, Christa, Miranda, Ana Catarina, Partecke, Jesko, Quetting, Michael   +8 more
core   +2 more sources

Role of Corticosterone in Lipid Metabolism in Broiler Chick White Adipose Tissue

The Journal of Poultry Science, 2022
Excessive accumulation of body fat in broiler chickens has become a serious problem in the poultry industry. However, the molecular mechanism of triglyceride accumulation in chicken white adipose tissue (WAT) has not been elucidated.
Kazuhisa Honda, Kiyotaka Kurachi, Shoko Takagi, Takaoki Saneyasu, Hiroshi Kamisoyama   +4 more
doaj   +1 more source

Experimental Food Restriction Reveals Individual Differences in Corticosterone Reaction Norms with No Oxidative Costs

PLoS ONE, 2014
Highly plastic endocrine traits are thought to play a central role in allowing organisms to respond rapidly to environmental change. Yet, not all individuals display the same degree of plasticity in these traits, and the costs of this individual ...
Ádám Z. Lendvai, J. Ouyang, L. Schoenle, Vincent J. Fasanello, M. Haussmann, F. Bonier, I. Moore   +6 more
semanticscholar   +1 more source

Astrocytic PERK Deficiency Drives Prefrontal Circuit Dysfunction and Depressive‐Like Behaviors

Advanced Science, EarlyView.
Chen et al. show that the endoplasmic reticulum (ER) stress sensor PERK is downregulated in prefrontal cortex (PFC) astrocytes in major depressive disorder and in chronic‐stress mouse models. In young mice, astrocyte‐specific PERK loss reduces the synaptogenic cue thrombospondin‐1 (TSP1), leading to synaptic and circuit deficits and depressive‐like ...
Kai Chen, Riya Gupta, Yosuke M. Morizawa, Yu Qin, Xingyu Du, Cynthia Pang, Osama Al‐Dalahmah, Maura B. Dupont, Guang Yang   +8 more
wiley   +1 more source