Results 41 to 50 of about 81,990 (314)

Dexamethasone-associated metabolic effects in male mice are partially caused by depletion of endogenous corticosterone

Frontiers in Endocrinology, 2022
Synthetic glucocorticoids are clinically used to treat auto-immune and inflammatory disease. Despite the high efficacy, glucocorticoid treatments causes side effects such as obesity and insulin resistance in many patients.
Lisa L. Koorneef, Lisa L. Koorneef, Merel van der Meulen, Merel van der Meulen, Sander Kooijman, Sander Kooijman, Elena Sánchez-López, Jari F. Scheerstra, Jari F. Scheerstra, Maaike C. Voorhoeve, Maaike C. Voorhoeve, Ajith N. Nadamuni Ramesh, Ajith N. Nadamuni Ramesh, Patrick C. N. Rensen, Patrick C. N. Rensen, Martin Giera, Jan Kroon, Jan Kroon, Onno C. Meijer, Onno C. Meijer   +19 more
doaj   +1 more source

HPLC MS-MS Analysis Shows Measurement of Corticosterone in Egg Albumen Is Not a Valid Indicator of Chicken Welfare

Animals, 2020
Assessment of animal welfare can include analysis of physiological parameters, as well as behavior and health. Levels of adrenocortical hormones such as cortisol (and corticosterone in chickens) have been relied on as indicators of stress.
Malcolm P. Caulfield, Matthew P. Padula
doaj   +1 more source

Aldosterone and Dexamethasone Activate African Lungfish Mineralocorticoid Receptor: Increased Activation After Removal of the Amino-Terminal Domain [PDF]

arXiv, 2021
Aldosterone, the main physiological mineralocorticoid in humans and other terrestrial vertebrates, first appears in lungfish, which are lobe-finned fish that are forerunners of terrestrial vertebrates. Aldosterone activation of the MR regulates internal homeostasis of water, sodium and potassium, which was critical in the conquest of land by ...
arxiv  

Experimental Food Restriction Reveals Individual Differences in Corticosterone Reaction Norms with No Oxidative Costs

PLoS ONE, 2014
Highly plastic endocrine traits are thought to play a central role in allowing organisms to respond rapidly to environmental change. Yet, not all individuals display the same degree of plasticity in these traits, and the costs of this individual ...
Ádám Z. Lendvai, J. Ouyang, L. Schoenle, Vincent J. Fasanello, M. Haussmann, F. Bonier, I. Moore   +6 more
semanticscholar   +1 more source

Ethnomedicinal Uses, Phytochemistry, Pharmacological Activities, and Toxicology of the Subfamily Gomphrenoideae (Amaranthaceae): A Comprehensive Review

Chemistry &Biodiversity, EarlyView.
ABSTRACT The subfamily Gomphrenoideae is composed of about 480 accepted species, many of which have been historically used as medicinal plants, reason why they have been studied in terms of chemical profile, biological activity, and safety. This review consolidates the advances in research on this subfamily over the past 47 years, emphasizing its ...
Dayanna Isabel Araque Gelves, Giulia Cristina de Andreoli Souza, Alvaro Jose Hernandez Tasco, Marcos José Salvador   +3 more
wiley   +1 more source

Corticosterone in Commercial Broilers

Journal of Applied Poultry Research, 2005
Abstract The welfare of commercially produced broilers is of concern to producers and consumers. When birds are reared under stressful conditions they often exhibit several adaptive responses. The major response is secretion of the stress hormone, corticosterone (CS), by the adrenal glands.
J. Rice, M. Ewing, J. P. Thaxton, P. Stayer   +3 more
openaire   +2 more sources

Effects of corticosterone pellets on baseline and stress-induced corticosterone and corticosteroid-binding-globulin [PDF]

General and Comparative Endocrinology, 2009
Exogenous administration of glucocorticoids is a widely used and efficient tool to investigate the effects of elevated concentrations of these hormones in field studies. Because the effects of corticosterone are dose and duration-dependent, the exact course of plasma corticosterone levels after exogenous administration needs to be known.
Bettina Almasi, Bettina Almasi, Claudia Müller, Claudia Müller, Creagh W. Breuner, Lukas Jenni, Alexandre Roulin, Susanne Jenni-Eiermann   +7 more
openaire   +3 more sources

Regulation by Progestins, Corticosteroids and RU486 of Activation of Elephant Shark and Human Progesterone Receptors: An Evolutionary Perspec [PDF]

arXiv, 2021
We investigated progestin and corticosteroid activation of the progesterone receptor (PR) from elephant shark (Callorhinchus milii), a cartilaginous fish belonging to the oldest group of jawed vertebrates. Comparison with human PR experiments provides insights into the evolution of steroid activation of human PR.
arxiv  

Mineralocorticoid receptors are indispensable for nongenomic modulation of hippocampal glutamate transmission by corticosterone.

Proceedings of the National Academy of Sciences of the United States of America, 2005
The adrenal hormone corticosterone transcriptionally regulates responsive genes in the rodent hippocampus through nuclear mineralocorticoid and glucocorticoid receptors.
H. Karst, S. Berger, Marc Turiault, F. Tronche, G. Schütz, M. Joëls   +5 more
semanticscholar   +1 more source

Predicting OCT2/MATEs‐Mediated Drug Interactions in Healthy Volunteers and Patients with Chronic Kidney Disease: Insights from Extended Clearance Concept, Endogenous Biomarkers, and In Vitro Inhibition Studies (Perspectives from the International Transporter Consortium)

Clinical Pharmacology &Therapeutics, EarlyView.
Organic cation transporter (OCT) 2 and multidrug and toxin extrusion (MATE) transporters play significant roles in the renal secretion of organic cations and drug–drug interactions (DDIs). Recent in vitro studies indicate that the Ki values for OCT2 exhibit substrate dependency and increase in potency with pre‐incubation.
Satoshi Asano, Aleksandra Galetin, Yoshiko Tomita, Kathleen M. Giacomini, Xiaoyan Chu, Xinning Yang, Toshimichi Nakamura, Hiroyuki Kusuhara, Yuichi Sugiyama   +8 more
wiley   +1 more source