Glucocorticoids rapidly inhibit oxytocin-stimulated adrenocorticotropin release from rat anterior pituitary cells, without modifying intracellular calcium transients [PDF]
Glucocorticoid hormones suppress the secretion of ACTH evoked by secretagogues such as CRF and arginine vasopressin. In this study, we investigated the effects of glucocorticoids on ACTH release induced by oxytocin (OT) and on intracellular free calcium ...
Dayanithi, G., Gratzl, Manfred, Link, H.
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Role of Corticosterone in Lipid Metabolism in Broiler Chick White Adipose Tissue
Excessive accumulation of body fat in broiler chickens has become a serious problem in the poultry industry. However, the molecular mechanism of triglyceride accumulation in chicken white adipose tissue (WAT) has not been elucidated.
Kazuhisa Honda +4 more
doaj +1 more source
Effects of environmental enrichment on behavioral responses to novelty, learning, and memory, and the circadian rhythm in cortisol in growing pigs [PDF]
Previously we showed that pigs reared in an enriched environment had higher baseline salivary cortisol concentrations during the light period than pigs reared under barren conditions.
Blokhuis, Harry J., +6 more
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Gut Bacteria Improve Depressive Symptoms by Degrading Cortisol into Androgen
Chronic stress is an important risk factor for stress‐related disorders such as depression. Stress hormone cortisol is essential for the pathogenesis of stress‐related disorders such as depression. Some gut microbiota degraded cortisol, and improve depressive symptoms.
Xiong Wang +12 more
wiley +1 more source
Stachyose Alleviates Corticosterone-Induced Long-Term Potentiation Impairment via the Gut–Brain Axis
Stress can induce learning and memory impairment; corticosterone is often used to study the effects and mechanisms of stress in animal models. Long-term potentiation (LTP) has been widely used for tackling the mechanisms of memory.
Yan Huang +4 more
doaj +1 more source
Organic Cation Transporter 3: A Cellular Mechanism Underlying Rapid, Non-Genomic Glucocorticoid Regulation of Monoaminergic Neurotransmission, Physiology, and Behavior [PDF]
Corticosteroid hormones act at intracellular glucocorticoid receptors (GR) and mineralocorticoid receptors (MR) to alter gene expression, leading to diverse physiological and behavioral responses.
Gasser, Paul J., Lowry, Christopher A.
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Astrocytic PERK Deficiency Drives Prefrontal Circuit Dysfunction and Depressive‐Like Behaviors
Chen et al. show that the endoplasmic reticulum (ER) stress sensor PERK is downregulated in prefrontal cortex (PFC) astrocytes in major depressive disorder and in chronic‐stress mouse models. In young mice, astrocyte‐specific PERK loss reduces the synaptogenic cue thrombospondin‐1 (TSP1), leading to synaptic and circuit deficits and depressive‐like ...
Kai Chen +8 more
wiley +1 more source
Depression, a prevalent neuropsychiatric disorder with unclear pathogenesis, involves dysfunctional adenylyl cyclase 8 (Adcy8) as a key risk factor. Chronic stress selectively reduces Adcy8 expression in the dorsal CA1 (dCA1) neurons. Depletion of Adcy8 in dCA1 excitatory neurons induces depressive‐like behaviors by impairing neuronal excitability and ...
Zi‐Jie Liu +14 more
wiley +1 more source
Corticosterone concentrations have been measured in amphibians by collecting blood or urine samples. However, blood sampling is invasive, and urine can be difficult to collect.
Emma Clarke +7 more
doaj +1 more source
Effect of Edwardsiella ictaluri Infection on Plasma Corticosterone Levels in Channel Catfish (Ictalurus punctatus) [PDF]
Channel catfish (Ictalurus punctatus) were innoculated with a new host specific bacterium, Edwardsiella ictaluri, to observe the influence of bacterial infection on plasma corticosterone levels at various temperatures.
Beadles, John K. +2 more
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