Results 1 to 10 of about 10,599 (209)

A Corticothalamic Circuit for Refining Tactile Encoding [PDF]

Cell Reports, 2018
Summary: A fundamental task for the brain is to determine which aspects of the continuous flow of information is the most relevant in a given behavioral situation.
Patrik Krieger
exaly   +6 more sources

Tle4 controls both developmental acquisition and early post-natal maturation of corticothalamic projection neuron identity

Cell Reports, 2023
Summary: Identities of distinct neuron subtypes are specified during embryonic development, then maintained during post-natal maturation. In cerebral cortex, mechanisms controlling early acquisition of neuron-subtype identities have become increasingly ...
Jeffrey Macklis, David A Sweetser
exaly   +3 more sources

Somatosensory control of thalamic relay neurons is regulated by two distinct layer 6 feedback systems [PDF]

iScience
Summary: The medial posterior (POm) and ventral posterior medial (VPM) thalamic nuclei sort and filter somatosensory information that is sent to the primary somatosensory cortex (S1). Corticothalamic feedback from distinct cell populations of S1 layer 6 (
Josephine Ansorge, Denise Manahan-Vaughan   +1 more
doaj   +2 more sources

Individual trajectories for recovery of neocortical activity in disorders of consciousness. [PDF]

PLoS Computational Biology
The evolution from disturbed brain activity to physiological brain rhythms can precede recovery in patients with disorders of consciousness (DoC). Accordingly, intriguing questions arise: What are the pathophysiological factors associated to disrupted ...
Prejaas K B Tewarie, Romesh Abeysuriya, Rajanikant Panda, Pablo Nùñez, Marie M Vitello, Glenn van der Lande, Olivia Gosseries, Aurore Thibaut, Steven Laureys, Gustavo Deco, Jitka Annen   +10 more
doaj   +2 more sources

Specific connectivity optimizes learning in thalamocortical loops [PDF]

Cell Reports
Summary: Thalamocortical loops have a central role in cognition and motor control, but precisely how they contribute to these processes is unclear. Recent studies showing evidence of plasticity in thalamocortical synapses indicate a role for the thalamus
Kaushik J. Lakshminarasimhan, Marjorie Xie, Jeremy D. Cohen, Britton A. Sauerbrei, Adam W. Hantman, Ashok Litwin-Kumar, Sean Escola   +6 more
doaj   +2 more sources

Corticothalamic feedback locally modulates network state [PDF]

Scientific Reports
As the cortex receives most of its input from the thalamus, cortical layer 6 (L6) in turn sends a massive glutamatergic projection back to the corresponding thalamic areas.
S. Borbély, A. Zalatnai, É. Gulyás, V. Balogh, M. Csernai, P. Barthó   +5 more
doaj   +2 more sources

EphrinA5 protein distribution in the developing mouse brain [PDF]

BMC Neuroscience, 2010
Background EphrinA5 is one of the best-studied members of the Eph-ephrin family of guidance molecules, known to be involved in brain developmental processes. Using in situ hybridization, ephrinA5 mRNA expression has been detected in the retinotectal, the
Deschamps Claire, Morel Milena, Janet Thierry, Page Guylène, Jaber Mohamed, Gaillard Afsaneh, Prestoz Laetitia   +6 more
doaj   +5 more sources

Layer 5 myelination gates corticothalamic coincidence detection [PDF]

Nature Communications
Myelin is essential for the rapid conduction of action potentials (APs) but its role in long-range processing of disparate inputs remains unclear. Here, using a cell-type-specific approach we recorded optogenetically evoked pyramidal neuron responses via
Nora Jamann, Jorrit S. Montijn, Naomi Petersen, Roeland Lokhorst, Daan van den Burg, Maayke Balemans, Stan L. W. Driessens, J. Alexander Heimel, Maarten H. P. Kole   +8 more
doaj   +2 more sources

Unified theory of alpha, mu, and tau rhythms via eigenmodes of brain activity [PDF]

Frontiers in Computational Neuroscience
A compact description of the frequency structure and topography of human alpha-band rhythms is obtained by use of the first four brain activity eigenmodes previously derived from corticothalamic neural field theory.
Rawan Khalil El Zghir, Rawan Khalil El Zghir, Natasha C. Gabay, Natasha C. Gabay, Natasha C. Gabay, P. A. Robinson, P. A. Robinson   +6 more
doaj   +2 more sources

Corticothalamic neurons in motor cortex have a permissive role in motor execution [PDF]

Nature Communications
The primary motor cortex (M1) is a central hub for motor learning and execution. M1 is composed of heterogeneous cell types with varying relationships to movement.
Lina Marcela Carmona, Anders Nelson, Lin T. Tun, An Kim, Rani Shiao, Michael D. Kissner, Vilas Menon, Rui M. Costa   +7 more
doaj   +2 more sources