Results 91 to 100 of about 515,964 (279)

Promoter Methylation Pattern Controls Corticotropin Releasing Hormone Gene Activity in Human Trophoblasts.

PLoS ONE, 2017
Placental CRH production increases with advancing pregnancy in women and its course predicts gestational length. We hypothesized that CRH gene expression in the placenta is epigenetically controlled setting gestational trajectories characteristic of ...
Xin Pan, Maria Bowman, Rodney J Scott, John Fitter, Roger Smith, Tamas Zakar   +5 more
doaj   +1 more source

Regression model predicting cortisol response in the first and second dexamethasone/corticotropin releasing hormone test (in terms of total area under the curve) using gender, age, dexamethasone-suppressed baseline cortisol, and baseline copeptin as predictor variables.

, 2014
Baseline values have been collected under the suppressive effects of DEX, but prior to stimulation with 100 µg of human corticotropin releasing hormone.
Jens Stepan (395842), Matthias Eder (21135), Klaus V. Wagner (511534), Kathrin Hafner (5657512), Marcus Ising (195804), Thomas Kirmeier (658032), Susanne Lucae (214969), Jürgen Zschocke (509033), Stefan Kloiber (658036), Mathias V. Schmidt (230754), Jan M. Deussing (170418), Theo Rein (363230), Nina Dedic (658034), Jakob Hartmann (511537), Andreas Zellner (658031), Florian Holsboer (20105), Nils C. Gassen (509031), Lorenz Kollmannsberger (658033), Georgia Balsevich (658035), Manfred Uhr (20107)   +19 more
core   +1 more source

Prostaglandin E2 (PGE2) signaling regulates fluid excretion and uric acid metabolism in the mosquito Anopheles gambiae

Insect Science, EarlyView.
Prostaglandin E2 (PGE2) signaling via its receptor has integral roles in mosquito physiology, mediating fluid excretion, stimulating hindgut contractions, and in modulating uric acid levels. Together, these results uncover previously unrecognized roles of prostaglandin signaling in osmotic balance and metabolic homeostasis in mosquitoes.
Hyeogsun Kwon, David R. Hall, Houda O. Maaroufi, Ryan C. Smith   +3 more
wiley   +1 more source

Potential Uses of Corticotropin‐Releasing Hormone Antagonists

Annals of the New York Academy of Sciences, 2006
Abstract: Corticotropin‐releasing hormone (CRH), its natural homologs urocortins (UCN) 1, 2, and 3, and several types of CRH receptors (R), coordinate the behavioral, endocrine, autonomic, and immune responses to stress. The potential use of CRH antagonists is currently under intense investigation. Selective antagonists have been used experimentally to
Zoumakis, E., Rice, K. C., Gold, P. W., Chrousos, G. P.   +3 more
openaire   +3 more sources

Sex‐Specific Involvement of Gut Microbiota in Behavioral and Endocrine Responses to Chronic Predator Odor in Brandt's Voles

Integrative Zoology, EarlyView.
18 days of predator odor exposure altered gut microbiota, increased anxiety‐like behaviors, and elevated hypothalamic–pituitary–adrenal axis activity in Brandt's voles, with males showing behavioral habituation and females remaining sensitive. Cecal microbiota transplantation experiments confirmed that only female recipients of microbiota from predator‐
Chen Gu, Ruiping Xu, Baofa Yin, Ruiyong Wu, Youheng Wei, Dehua Wang, Wanhong Wei   +6 more
wiley   +1 more source

Study of changes in the concentration of corticotropin-releasing hormone and corticosterone in rats in a state of depressive conditions under plant extract stress

Вестник медицинского института «Реавиз»: Реабилитация, врач и здоровье
Depression is a mental disorder characterized by sadness, loss of interest and pleasure, decreased ability to experience joy, feelings of guilt or low self-esteem, as well as sleep and appetite disturbances and increased fatigue.
P. M. Moskvitina, O. N. Pavlova, E. V. Lukenyuk   +2 more
doaj   +1 more source

Modulation of Sleep Homeostasis by Corticotropin Releasing Hormone in REM Sleep-Deprived Rats

International Journal of Endocrinology, 2010
Studies have shown that sleep recovery following different protocols of forced waking varies according to the level of stress inherent to each method.
Ricardo Borges Machado, Sergio Tufik, Deborah Suchecki   +2 more
doaj   +1 more source

The impact of stress on tumor growth: peripheral CRF mediates tumor-promoting effects of stress

Molecular Cancer, 2010
Introduction Stress has been shown to be a tumor promoting factor. Both clinical and laboratory studies have shown that chronic stress is associated with tumor growth in several types of cancer.
Stathopoulos Efstathios N, Ripoll Jorge, Rassouli Olga, Dermitzaki Erini, Androulidaki Ariadne, Mol Berber, Venihaki Maria, Arranz Alicia, Gomariz Rosa P, Margioris Andrew N, Tsatsanis Christos   +10 more
doaj   +1 more source

Effect of Social Rank on Gut Microbes and Their Metabolites of Greater Long‐Tailed Hamsters (Tscherskia triton)

Integrative Zoology, EarlyView.
Social rank in greater long‐tailed hamsters (Tscherskia triton) shapes gut microbiota composition and metabolite profiles. Dominant males exhibit a “high‐vigilance, metabolically activated” phenotype, with elevated aggression and specific gut microbiota enriched in energy‐harvesting taxa and fecal queuine.
Da Zhang, Xiaoming Xu, Zhibin Zhang
wiley   +1 more source

Role of corticotropin-releasing hormone as a thyrotropin-releasing factor in non-mammalian vertebrates

, 2006
The finding that thyrotropin-releasing hormone does not always act as a thyrotropin (TSH)-releasing factor in non-mammalian vertebrates has led researchers to believe that another hypothalamic factor may exhibit this function.
Kühn, Eduard, Van der Geyten, Serge, Darras, Veerle, De Groef, Bert   +3 more
core   +1 more source