Results 71 to 80 of about 33,444 (220)

The impact of stress on tumor growth: peripheral CRF mediates tumor-promoting effects of stress

Molecular Cancer, 2010
Introduction Stress has been shown to be a tumor promoting factor. Both clinical and laboratory studies have shown that chronic stress is associated with tumor growth in several types of cancer.
Stathopoulos Efstathios N, Ripoll Jorge, Rassouli Olga, Dermitzaki Erini, Androulidaki Ariadne, Mol Berber, Venihaki Maria, Arranz Alicia, Gomariz Rosa P, Margioris Andrew N, Tsatsanis Christos   +10 more
doaj   +1 more source

Effect of Social Rank on Gut Microbes and Their Metabolites of Greater Long‐Tailed Hamsters (Tscherskia triton)

Integrative Zoology, EarlyView.
Social rank in greater long‐tailed hamsters (Tscherskia triton) shapes gut microbiota composition and metabolite profiles. Dominant males exhibit a “high‐vigilance, metabolically activated” phenotype, with elevated aggression and specific gut microbiota enriched in energy‐harvesting taxa and fecal queuine.
Da Zhang, Xiaoming Xu, Zhibin Zhang
wiley   +1 more source

Study of changes in the concentration of corticotropin-releasing hormone and corticosterone in rats in a state of depressive conditions under plant extract stress

Вестник медицинского института «Реавиз»: Реабилитация, врач и здоровье
Depression is a mental disorder characterized by sadness, loss of interest and pleasure, decreased ability to experience joy, feelings of guilt or low self-esteem, as well as sleep and appetite disturbances and increased fatigue.
P. M. Moskvitina, O. N. Pavlova, E. V. Lukenyuk   +2 more
doaj   +1 more source

Amylin analogues as a novel perspective in anti‐obesity therapy

British Journal of Pharmacology, EarlyView.
Abstract Public health systems face a major challenge because of the worldwide obesity epidemic. The number of obese individuals has increased dramatically and, even in Switzerland which may be considered a relatively “lean” country, the numbers are alarmingly high and have reached almost 50% of the adult population.
Thomas A. Lutz
wiley   +1 more source

Atrial natriuretic peptide counteracts aldosterone secretion by preventing acute angiotensin II‐induced cAMP signalling

British Journal of Pharmacology, EarlyView.
Background and Purpose Aldosterone plays a key role in blood pressure and volume regulation. Enhanced aldosterone secretion contributes to cardiovascular and renal diseases. Therefore, inhibitors of aldosterone receptors and synthase are essential drugs for the treatment of hypertension and heart failure.
Sanika Mohagaonkar, Egor B. Skryabin, Bettina M. Buchholz, Michaela Kuhn, Celso E. Gomez‐Sanchez, Stepan Gambaryan, Viacheslav O. Nikolaev   +6 more
wiley   +1 more source

Modulation of Sleep Homeostasis by Corticotropin Releasing Hormone in REM Sleep-Deprived Rats

International Journal of Endocrinology, 2010
Studies have shown that sleep recovery following different protocols of forced waking varies according to the level of stress inherent to each method.
Ricardo Borges Machado, Sergio Tufik, Deborah Suchecki   +2 more
doaj   +1 more source

Crossover of the hypothalamic pituitary-adrenal/interrenal (HPA), -thyroid (HPT), and -gonadal (HPG) axes in testicular development

Frontiers in Endocrinology, 2014
Besides the well-known function of thyroid hormones (THs) for regulating metabolism, it has recently been discovered that THs are also involved in testicular development in mammalian and non-mammalian species.
Diana C. Castañeda Cortés, Valerie S. Langlois, Juan I. Fernandino   +2 more
doaj   +1 more source

Gut microbiota as a novel therapeutic target for eating disorders and obesity

British Journal of Pharmacology, EarlyView.
The graphical abstract highlights the bidirectional interaction between the gut microbiota and central homeostatic and hedonic mechanisms regulating food intake, which contributes to overweight and obesity. It also illustrates emerging microbiota‐based biomarkers and therapeutic strategies (including prebiotics, probiotics, postbiotics, synbiotics and ...
Solveiga Samulėnaitė, Victor Mathis, Emmanuel Darcq, Aurelijus Burokas, Elena Martín‐García, Rafael Maldonado   +5 more
wiley   +1 more source

Case Report: ACTH- and CRH-secreting pheochromocytoma as a very rare cause of ectopic Cushing syndrome

Frontiers in Endocrinology
Ectopic adrenocorticotropic hormone (ACTH) syndrome (EAS) represents a rare clinical entity characterized by severe hypercortisolemia. Pheochromocytoma, a neuroendocrine neoplasm originating from chromaffin cells within the adrenal medulla, is itself an ...
Barbara Bromińska, Nadia Sawicka-Gutaj, Ewelina Szczepanek-Parulska, Małgorzata Lange-Ratajczak, Tomasz Wierzbicki, Małgorzata Janicka-Jedyńska, Rafał Czepczyński, Marek Ruchała   +7 more
doaj   +1 more source

Chronic Stress Reduces Nectin-1 mRNA Levels and Disrupts Dendritic Spine Plasticity in the Adult Mouse Perirhinal Cortex

Frontiers in Cellular Neuroscience, 2018
In adulthood, chronic exposure to stressful experiences disrupts synaptic plasticity and cognitive function. Previous studies have shown that perirhinal cortex-dependent object recognition memory is impaired by chronic stress. However, the stress effects
Qian Gong, Yun-Ai Su, Yun-Ai Su, Chen Wu, Tian-Mei Si, Tian-Mei Si, Jan M. Deussing, Mathias V. Schmidt, Xiao-Dong Wang   +8 more
doaj   +1 more source