Results 81 to 90 of about 515,964 (279)

Proteo‐transcriptomic insights into the venom composition of the ectoparasitoid Eupelmus urozonus

Pest Management Science, EarlyView.
Integrated venom‐gland transcriptomics and venom proteomics of Eupelmus urozonus identified 316 venom proteins, including 75 secreted candidates, revealing diverse hydrolases, proteases/inhibitors and many uncharacterized effectors. Abstract BACKGROUND Ectoparasitoid venoms are ‘cocktails’ of bioactive molecules injected during oviposition to paralyze ...
Federica De Stefano, Carmen Scieuzo, Rosanna Salvia, Riccardo Moretti, Flora Cozzolino, Maria Monti, Heiko Vogel, Patrizia Falabella   +7 more
wiley   +1 more source

Corticotropin-Releasing Hormone, Microglia and Mental Disorders

International Journal of Immunopathology and Pharmacology, 2014
Microglia derive from mononuclear myeloid progenitors and are a major glial complement of the central nervous system. When microglia are activated they secrete inflammatory cytokines and toxic mediators which amplify the inflammatory response. In addition, the microglia inflammatory products are implicated in the neuronal destruction usually observed ...
Kritas, Spyridon K., Saggini, A., Cerulli, G., Caraffa, A., Antinolfi, P., Pantalone, A., Rosati, M., Tei, M., Speziali, A., Saggini, R., Conti, P.   +10 more
openaire   +4 more sources

Corticotropin-releasing hormone interacts with interleukin-1 to regulate prostaglandin H synthase-2 expression in human myometrium during pregnancy and labor [PDF]

, 2013
Context: The onset of labor appears to involve the activation of myometrial inflammatory pathways, and transcription factors such as nuclear factor-κB (NF-κB) control expression of the contraction-associated proteins required to induce a procontractile ...
Grammatopoulos, Dimitris, Bari, Muhammad F., Lu, Buyu, Markovic, Danijela, Lu, B., Vatish, Manu   +5 more
core   +1 more source

From Consumer Plastics to Aquatic Toxicants: Oxidative and Endocrine Effects of Microplastics on Fathead Minnow (Pimephales promelas) Larvae

Environmental Toxicology, EarlyView.
ABSTRACT Secondary microplastics (MPs) from single‐use consumer products are rapidly becoming one of the most persistent and widespread pollutants of our time. Freshwater systems act as early sinks for MPs where fragmentation and additive leaching expose aquatic life to a broad spectrum of toxic compounds.
Alisha M. Janiga‐MacNelly, Andrew Barrick, Tham C. Hoang, Ramon Lavado   +3 more
wiley   +1 more source

Fecal Glucocorticoid and Androgen Metabolites in Eastern Grey Kangaroos (Macropus giganteus) Following Environmental Relocation

Zoo Biology, EarlyView.
Fecal glucocorticoid (GCM) and androgen metabolite (AM) concentrations were monitored for 3 months following the relocation of three eastern gray kangaroos (Macropus giganteus) between zoological facilities. Both metabolites showed high concentrations during the early postrelocation period, followed by a rapid decline and stabilization, suggesting ...
Laura Menchetti, Rupert Palme, Livio Galosi, Giacomo Rossi, Elena Fraticelli, Gaia Andrea Bevinetto, Gioia Gaiot, Renato Piccinini, Raffaello Gambi, Matteo Cerquetella   +9 more
wiley   +1 more source

Update on the role of ovarian corticotropin‐releasing hormone

Annals of the New York Academy of Sciences, 2010
Corticotropin‐releasing hormone (CRH) is a 41‐amino acid peptide synthesized by neurons of the parvocellular and paraventricular hypothalamic nuclei. Central CRH is the principal regulator of the stress system influencing several systems in the brain and influenced by them.
Kiapekou, E., Zapanti, E., Mastorakos, G., Loutradis, D.   +3 more
openaire   +3 more sources

The Scoop on Honey Badger Poop: Validation of a Non‐Invasive Method for Assessing Physiological Responses in Captivity

Zoo Biology, EarlyView.
ABSTRACT Captive honey badgers (Mellivora capensis) are routinely exposed to environmental and husbandry‐related stressors that differ markedly from their natural conditions; however, physiological welfare assessments in this species remain limited. This study aimed to validate a non‐invasive approach to evaluate stress‐related fecal glucocorticoid ...
Megan Hutson, André Ganswindt, Andrea B. Webster   +2 more
wiley   +1 more source

Developmental profile of corticotropin releasing hormone messenger RNA in the rat inferior olive [PDF]

, 1996
Corticotropin releasing hormone is a neurotransmitter in the inferior olive complex of marsupials and mammals. The ontogeny of corticotropin releasing hormone gene expression in the rat inferior olive has not been described.
Chang, D, D. Chang, T.Z. Baram, Yi, Su‐Jin, Su-Jin Yi, Baram, TZ   +5 more
core   +1 more source

Calcitonin‐like diuretic hormone influences reproduction in adult female Rhodnius prolixus

Insect Science, EarlyView.
Highlights • CT/DH‐like immunoreactivity is present in female reproductive tissues • CT/DH receptor transcripts are expressed in the fat body and ovaries • RNAi knockdown of CT/DH receptors reduces egg number and hatching rate • Rhopr‐CT/DH increases RhoprVg1 and RhoprVgR expression in ovaries in vitro • Rhopr‐CT/DH stimulates oviduct contractions in a
Areej N. Al‐Dailami, Ian Orchard, Angela B. Lange   +2 more
wiley   +1 more source

Clinical Perspectives of Urocortin and Related Agents for the Treatment of Cardiovascular Disease

International Journal of Endocrinology, 2012
The effects of corticotropin-releasing hormone, also known as corticotropin-releasing factor (CRF), on the cardiovascular system have been intensively researched since its discovery. Moreover, the actions of urocortin (Ucn) I on the cardiovascular system
Keiichi Ikeda, Kouki Fujioka, Yoshinobu Manome, Katsuyoshi Tojo   +3 more
doaj   +1 more source