Results 171 to 180 of about 515,964 (279)

Blockade of Corticotropin-Releasing Hormone Receptor 1 Receptors in the Arcuate Nucleus May Effectively Treat Infantile Epileptic Spasms Syndrome. [PDF]

Epilepsy Curr
Goodman JH.
europepmc   +1 more source

Clinical Applications of Corticotropin Releasing Hormone [PDF]

Mayo Clinic Proceedings, 1990
openaire   +2 more sources

Epilepsy‐associated SCN2A‐L1342P mutation drives network hyperexcitability and widespread transcriptomic changes in human cortical organoids

Epilepsia, Volume 67, Issue 10, Page 5514-5530, October 2026.
Abstract Objective SCN2A pathogenic mutations, such as the recurrent heterozygous Nav1.2‐L1342P, are monogenic causes of epilepsy. In this human‐induced pluripotent stem cell–derived model system, we aim to investigate the molecular and cellular mechanisms underlying SCN2A‐L1342P‐associated pathology. Methods Using a human male induced pluripotent stem
Maria I. Olivero‐Acosta, Morgan Robinson, Zhefu Que, Zaiyang Zhang, Karen V. Salazar‐Salazar, Hope Elizabeth Harlow, Vinayak Shankar, Seoyeon Hong, Muhan Wang, Conrad M. Otterbacher, Hina Kadono, Manasi Halurkar, Harish Kothandaraman, Nadia Atallah Lanman, Trang Nguyen, Kyle Wettschurack, Benjamin Zirkle, Layan Yunis, Ningren Cui, Xiaoling Chen, Jingliang Zhang, Jiaxiang Wu, William C. Skarnes, Chongli Yuan, Feng Guo, Megan Abbott, Yang Yang   +26 more
wiley   +1 more source

Neuropathic Pain Comorbid Cognitive Impairment and Vitamin D: A Narrative Review From Mechanisms to Clinical Management

Food Science &Nutrition, Volume 14, Issue 10, October 2026.
Vitamin D is an essential fat‐soluble nutrient primarily obtained through cutaneous synthesis triggered by ultraviolet exposure and dietary intake. After systemic metabolism and activation, it binds to vitamin D receptors widely distributed in the central and peripheral nervous systems, exerting pleiotropic neuroprotective and regulatory biological ...
Nan Zhao, Yang Yang, Wanqiu Yu, Yuhang Zhu, Zhaoqiong Zhu   +4 more
wiley   +1 more source

Sex and Stress Govern the Function and Innervation of a Basolateral Amygdala to Nucleus Accumbens Corticotropin-Releasing Hormone/GABA-Expressing Projection. [PDF]

J Neurosci
Taniguchi L, Goodpaster CM, Chen Y, de Carvalho GB, Birnie MT, Paul A, Chiang A, Chen LY, Baram TZ, DeNardo LA.   +9 more
europepmc   +1 more source

Corticotropin-Releasing Hormone [PDF]

, 2015
openaire   +1 more source

Coreopsis tinctoria Nutt. Polyphenols Ameliorate CUMS‐Induced Depressive Behaviors and Hippocampal Neuronal Damage in Mice

Food Science &Nutrition, Volume 14, Issue 10, October 2026.
The capitula of Coreopsis tinctoria Nutt. polyphenol extract (CCTE) attenuate CUMS‐induced depressive‐like behaviors and hippocampal neuronal damage in mice. Three flavonoid aglycones—okanin, isookanin, and taxifolin—cross the blood–brain barrier and synergistically inhibit MAO‐A, restoring serotonergic tone; concurrently, CCTE normalizes HPA‐axis ...
Haixia Han, Yujing Feng, Zhen Wang, Rui Ma, Jingjing Sun, Xiuli Yang, Yue Cui, Juan Wang, Mingxi Jia   +8 more
wiley   +1 more source

Oxytocin ameliorates early life stress-induced anxiety-like behavior by normalizing corticotropin-releasing hormone neuron activity in the PVN. [PDF]

iScience
Li C, Xu Y, Lin B, Huang X, Huang Z, Zheng F, Zhu L, Zhu Y, Yang C.   +8 more
europepmc   +1 more source

Markers of Systemic Metabolic Dysfunction in Vitiligo and Their Potential Role in Disease Pathogenesis: A Narrative Review

Health Science Reports, Volume 9, Issue 10, October 2026.
ABSTRACT Background Vitiligo is a chronic autoimmune disease characterized by the progressive destruction of melanocytes, resulting in depigmented skin macules. While traditionally viewed as a cutaneous disorder driven by a specific CD8+ T cell‐mediated interferon‐γ (IFN‐γ) signature, emerging research suggests that vitiligo may be a systemic condition
Federica Papaccio, Simona Scano, Barbara Bellei   +2 more
wiley   +1 more source

The metabolic role of corticotropin-releasing hormone receptor 2 and its UCN peptides: emerging therapeutic potential. [PDF]

Skelet Muscle
Vidal P, Janzen N, Brozinick JT.
europepmc   +1 more source