Results 191 to 200 of about 515,964 (279)

Corticotropin-releasing hormone as a candidate biomarker for parkinsonian disorders. [PDF]

Brain Commun
Fernandes Gomes B, Kumar A, Ashton NJ, Hall S, Stomrud E, Smith R, Zetterberg H, Blennow K, Mattsson-Carlgren N, Hansson O.   +9 more
europepmc   +1 more source

Oncological Outcomes and Safety Profiles of Adjuvant Nivolumab in Muscle‐Invasive Urothelial Carcinoma

International Journal of Urology, Volume 33, Issue 10, October 2026.
ABSTRACT Objectives Perioperative immunotherapy has become the standard of care in patients with high‐risk muscle‐invasive urothelial carcinoma (MIUC). This study aimed to clarify oncological outcomes and safety profiles of adjuvant nivolumab therapy in MIUC, focusing on upper tract urothelial carcinoma (UTUC).
Satoshi Katayama, Tatsushi Kawada, Keiichiro Mori, Kosuke Iwatani, Shota Inoue, Tomofumi Watanabe, Ichiro Tsuboi, Tomoaki Yamanoi, Takehiro Iwata, Kazuma Tsuboi, Wataru Murao, Tetsuya Nakada, Kohei Ogawa, Akihiro Matsukawa, Takafumi Yanagisawa, Shingo Nishimura, Kensuke Bekku, Koichiro Wada, Takahiro Kimura, Motoo Araki   +19 more
wiley   +1 more source

Corticotropin-Releasing Hormone Stimulates Proopiomelanocortin Transcription via the CaMKK/CaMKIV Pathway in the AtT20 Cell Line. [PDF]

Cureus
Jiang W, Zhang H, Imachi H, Kobayashi T, Fukunaga K, Saheki T, Yoshimura T, Dong T, Zhang G, Murao K.   +9 more
europepmc   +1 more source

The Role of Kappa‐Opioid Receptor/Dynorphin System in Modulating Neural‐Circuits of Depression and Anxiety—A Review

Journal of Cellular and Molecular Medicine, Volume 30, Issue 19, October 2026.
ABSTRACT Major depression and anxiety disorders are psychiatric disorders that involve a great number of people. There is a growing need for new and better pharmacological treatments for these diseases. Kappa‐opioid receptor (KOR) antagonists seem to be a promising new pathway for the development of new antidepressants and anxiolytics, but a great ...
Cristian Ciotei, Horia Păunescu, Cristina Lungu, Adriana‐Alexandra Marica, Mihai Florin Tănase, Ruxandra‐Cristina Marin, Mihnea Costescu, Ion Fulga, Oana Andreia Coman   +8 more
wiley   +1 more source

The Association of Perceived Stress, Glucocorticoids Receptors, and Corticotropin-Releasing Hormone Gene Expression During Pregnancy. [PDF]

Biol Res Nurs
Brennen M, Tappen R, Johnson V.
europepmc   +1 more source

Prolactin receptor signalling contributes to the attenuation of stress‐induced hyperthermia during pregnancy

Journal of Neuroendocrinology, Volume 38, Issue 10, October 2026.
Abstract During pregnancy, thermoregulation is tightly controlled to protect the foetus from harmful elevated temperatures. Stress‐induced hyperthermia is a component of the stress response that increases alertness to a perceived threat. Previous literature has shown that like other aspects of the stress response, stress‐induced hyperthermia is ...
Andrew M. Stewart, David R. Grattan, Teodora R. Georgescu   +2 more
wiley   +1 more source

The acid-sensing ion channel 1a modulates anxiety- and depression-related behaviors via its influencing on the activity of corticotropin-releasing hormone-expressing neurons in the hypothalamic paraventricular nucleus in male mice. [PDF]

Transl Psychiatry
Yue J, Zhang Q, Wang M, Yao X, Wang M, Liu L, Huang Z, Xing Y, Yan J, Yan Z, Song XL, Wang W.   +11 more
europepmc   +1 more source

Cushing's syndrome is associated with an advanced chronotype

Journal of Neuroendocrinology, Volume 38, Issue 10, October 2026.
Abstract Cushing's syndrome is characterised by chronic glucocorticoid excess that abolishes the physiological circadian cortisol rhythm. We investigated whether this circadian disruption alters chronotype. In a single‐centre case–control study, chronotype was assessed using the Munich ChronoType Questionnaire (MCTQ; n = 119) and wrist actigraphy (n ...
Hanna Nowotny, Adriana Albani, Mina Mazari, Stephanie Zopp, Martha Merrow, Nicole Reisch, Luis Gustavo Perez‐Rivas, Marily Theodoropoulou   +7 more
wiley   +1 more source

Corticotropin-releasing hormone inhibits autophagy by suppressing PTEN to promote apoptosis in dermal papilla cells. [PDF]

Ann Med
Liang W, Liang W, Chen X, Ni N, Zhuang C, Yu Z, Xu Z, Li Y, Lin C, Huang K.   +9 more
europepmc   +1 more source

The Skin‐Lightening Efficacy and Mechanisms of Botanical Extracts: A Comprehensive Review

Journal of Cosmetic Dermatology, Volume 25, Issue 10, October 2026.
ABSTRACT Background Skin pigmentation is regulated by a complex network involving melanogenesis, melanosome transfer, oxidative stress, environmental stimuli, and epidermal turnover. Botanical extracts and phytochemicals have attracted increasing interest as potential skin‐lightening agents. This review evaluates their efficacy, mechanisms, and safety.
Siting Yang, Mingning Ding, Chenglong Ye, Jingning Shen, Lihua Zhang, Anquan Yang, Lihao Gu   +6 more
wiley   +1 more source