Results 171 to 180 of about 150,986 (239)

Monogenic and syndromic obesity in children: Clinical recognition, genetics, and precision management

Pediatric Investigation, EarlyView.
Monogenic and syndromic obesity in children often arises from defects in the leptin–melanocortin pathway. Understanding these rare genetic causes not only clarifies mechanisms of appetite regulation but also enables precision therapies, offering hope beyond lifestyle interventions.
Hadel Khalil, Eugene Feigin, Hussein Zaitoon   +2 more
wiley   +1 more source

Ectopic Cushing Syndrome Secondary to Corticotropin-secreting Wilms Tumor: A Rare Paraneoplastic Phenomenon. [PDF]

JCEM Case Rep
Palai S, Sahoo BK, Mishra S, Mishra S, Pattanaik S, Jena D.   +5 more
europepmc   +1 more source

Evidence map and gap analysis of metabolic change in pediatric growth hormone deficiency treated with growth hormone

Pediatric Investigation, EarlyView.
This evidence map of 63 studies (n = 6158) showed growth hormone therapy in children with growth hormone deficiency has neutral glucose effects, mixed lipid outcomes, potential benefits for bone mineral density, bone mineral content, and parathyroid hormone, but generally no impact on thyroid function, body composition, or body mass index.
Wei Wu, Ningyi Song, Yue Zhao, Caiqi Du, Yuning Zhao, You Wu, Xiaoping Luo   +6 more
wiley   +1 more source

The effect of open-label placebo on anxiety, cortisol, and pain levels in children with procedural pain. [PDF]

Front Pediatr
Friedel AL, Szallies T, Oberlohmann J, Peters L, Benson S, Schedlowski M, Tschiedel E.   +6 more
europepmc   +1 more source

Conjugated Polymers Engineered for Flexible/Stretchable Electronics

Journal of Polymer Science, EarlyView.
This review highlights glass transition temperature (Tg) as the central parameter linking molecular structure to device performance in conjugated polymers. By tuning backbone rigidity, side‐chain architecture, and dynamic bonding, Tg governs the balance between π–π stacking–enabled charge transport and mechanical compliance.
Yunchong Yang, Josh Bass, Weijia Yan, Ashwath Anand, Chunka Zhou, Jingjing Qiu   +5 more
wiley   +1 more source

Early hypocortisolism with persistent remission following osilodrostat in a patient with long-standing Cushing disease. [PDF]

JCEM Case Rep
Sasson L, Shimon I.
europepmc   +1 more source

A walk in the park—Identifying healthy greenspaces using scents

PLANTS, PEOPLE, PLANET, EarlyView.
As urbanisation accelerates globally, access to nature is increasingly recognised as vital for public health and wellbeing. We captured and analysed plant‐emitted airborne ‘scent signatures’ across Oxford's urban greenspaces to assess their potential health relevance.
William T. Kay, Anya Lindström Battle, Mahal Humberstone, Molly Tucker, Kieran E. Storer, Geoffrey Kite, Katherine Willis   +6 more
wiley   +1 more source

Cortisol treatment impairs path integration and alters grid-like representations in the male human entorhinal cortex. [PDF]

PLoS Biol
Akan O, Chandreswaran V, Soldan HD, Bierbrauer A, Axmacher N, Wolf OT, Merz CJ.   +6 more
europepmc   +1 more source

Safety of 12‐Months Administration of Ashwagandha (Withania somnifera) Standardized Root Extract in Healthy Adults: A Prospective, Observational Study

Phytotherapy Research, EarlyView.
ABSTRACT Ashwagandha, an adaptogen, is an important herb of Ayurveda used as a Rasayana for its various health benefits. This prospective, multi‐center, observational clinical study evaluates the safety (clinical and laboratory) of a standardized Ashwagandha Root Extract (ARE) on long‐term administration over 12 months. Male and female adults (N = 191)
Jaising Salve, Sanjeev Kale, Banwari Lal Prajapati, Adele Sparavigna, Mark Savant, John Ademola, Deepak Langade   +6 more
wiley   +1 more source

Sex-specific effect of cortisol on cerebral glucose metabolism across Alzheimer's disease spectrum: a neuroimaging study. [PDF]

Front Neurol
Alqarni A, Alkhybari E, Alshuhri MS, Aljuhani M, Hadadi I, Alosaimi MH, Alshaari H, Alqahtani MM, Abd-Elghany AA, Alzheimer's Disease Metabolomics Consortium.   +9 more
europepmc   +1 more source