Results 201 to 210 of about 215,874 (309)

Complement C3 mediates adolescent social isolation‐induced hippocampal synaptic deficits and sex‐specific emotional dysfunction

Interdisciplinary Medicine, EarlyView.
Adolescent social isolation disrupts hippocampal function and exacerbates emotional symptoms, with sex‐specific patterns, as shown by human studies. In mice, social isolation decreased hippocampal synaptic density and calcium signaling, upregulated complement proteins, and activated complement‐mediated microglial synaptic phagocytosis.
Yuwan Qi, Siying Weng, Qiao Yin, Mengqi Li, Liang Shen, Enyou Qiao, Lu Gao, Yihan Wang, Yuxuan Li, Weifeng Luo, Qilin Zhang, Jing Wang, Jianfeng Feng, Qifei Cong   +13 more
wiley   +1 more source

Comprehensive biochemical and radiological assessment of clinical characterization pertaining to bilateral adrenal masses: a multi-center cross-sectional investigation. [PDF]

Endocrine
Akkus G, Kolsuz İ, Arslan YK, Pişkin F, Evran M, Sert M, Tetiker T, İnce YE, Örs A, Yılmaz N, Ceylan Ö, Öğmen B, Erdoğan BT, Aydın C, Çakır B, Üstay Ö, Solak YG, Yaylalı GF, Eraydın A, Fenkçi SM, Topsakal Ş, Öztürk Y, Kocabaş M, Sözen M, Çetinarslan B, Cantürk Z, Selek A, Gezer E, Öktem F, Dilli MŞ, Acıbucu F, Görar S, Yağcı H, Gökbulut P, Ertörer ME, Bağır GŞ, Üç ZA, Saygılı ES, Topuz BT, Güneş M, Altuntaş SÇ, Güneş E, Keskin L, Aksoy KU.   +43 more
europepmc   +1 more source

Whose Care Matters? The Protective Role of Perceived Care in the Long‐Term Physical Health Consequences of Adolescent Loneliness

Journal of Adolescence, EarlyView.
ABSTRACT Introduction Loneliness has been associated with physical health outcomes, including an increased risk of cardiovascular disease (CVD). While much of the research has focused on older adults, less is known about whether loneliness during adolescence is related to CVD risk later in life.
Keun Young Kwon, Ha Ly Choi, Skylar Biyang Sun, Jinho Kim   +3 more
wiley   +1 more source

Exposure to Endocrine Disruptors and Stress Hormones Across Pregnancy Trimesters: Links with Maternal Telomere Length. [PDF]

J Xenobiot
Vakonaki E, Hatzidaki E, Baliou S, Marmara M, Alegakis A, Mylonaki E, Volonaki Z, Makrygiannakis F, Tsatsakis A, Tzatzarakis MN.   +9 more
europepmc   +1 more source

A Novel Air‐Liquid Interface Exposure System for Continuous Gas Exposure of Airway Epithelial Cells: Exposure of NO2 With Viral Co‐Challenge

Journal of Applied Toxicology, EarlyView.
ABSTRACT Most in vitro toxicological research investigating the effects of inhaled compounds employ short‐term exposures of a couple of hours, or repeated, intermittent exposures for a limited number of days with exposure free periods, whereas in reality, we are continuously exposed, albeit to variable concentrations.
Marcia M. Oldenburger, Evert Duistermaat, Pieter S. Hiemstra, Flemming R. Cassee, Yvonne C. M. Staal   +4 more
wiley   +1 more source

Unsupervised clustering analysis reveals distinct postoperative cortisol trajectories following pituitary adenoma resection in Cushing's disease. [PDF]

J Neurooncol
Khazanchi R, Govind S, Jain R, Vignolles-Jeong J, Munjal V, Chaliparambil R, Damante M, Chandler JP, Ghalib L, Huang W, Magill ST, Prevedello DM.   +11 more
europepmc   +1 more source

Bisphenol Analog‐Induced Cytotoxicity: Unraveling Endoplasmic Reticulum (ER) Stress and Apoptotic Pathways

Journal of Applied Toxicology, EarlyView.
ABSTRACT Bisphenol A (BPA) is increasingly replaced by structural analogs, yet their safety remains insufficiently characterized. This study investigated whether BPA and selected analogs, bisphenol AF (BPAF), bisphenol AP (BPAP), bisphenol P (BPP), and bisphenol E (BPE), induce cytotoxicity through activation of endoplasmic reticulum (ER) stress and ...
Rafia Afroze Rifa, Ramon Lavado
wiley   +1 more source

Measuring cortisol in Cushing syndrome: diagnosis, monitoring, and cortisol circadian rhythm improvement.

J Clin Endocrinol Metab
Hamidi O, St-Jean M, Lacroix A, Bancos I.   +3 more
europepmc   +1 more source

Outcomes of endoscopic transsphenoidal pituitary surgery in patients with Cushing's disease: A retrospective review. [PDF]

Surg Neurol Int
Gupta V, Gupta P.
europepmc   +1 more source

Acute Modafinil Exposure Induces Neurobehavioral Alterations in Zebrafish: Implications for Off‐Label Cognitive Enhancement

Journal of Applied Toxicology, EarlyView.
ABSTRACT Modafinil (2‐(benzhydrylsulfinyl)acetamide) is a psychostimulant commonly prescribed for sleep disorders such as narcolepsy, excessive daytime sleepiness, and obstructive sleep apnea. Recently, its use has extended beyond clinical indications, with neurotypical individuals adopting it as a smart drug to enhance alertness and cognitive ...
Luciane Dellazari da Silva do Prado, Nicole Berton, Nicoli da Rosa Amaral, Inara Carbonera Biazus, Laíse Mattiollo, Jéssica Nardi, Karen Júlia de Souza dos Santos, Natália Freddo, Leonardo José Gil Barcellos, Luciana Grazziotin Rossato‐Grando   +9 more
wiley   +1 more source