A fast, sensitive, and selective liquid chromatography-tandem mass spectrometry (LC-MS/MS) method was validated and then the levels of cortisol and cortisone from sera of healthy adults were determined by the LC-MS/MS method.
Sanghoo Lee+10 more
semanticscholar +1 more source
11β-Hydroxysteroid dehydrogenase type 1 (11βHSD1) is a therapeutic target in metabolic syndrome because it catalyses reductase regeneration of cortisol from cortisone in adipose and liver.
Katherine A. Hughes+9 more
semanticscholar +1 more source
Management options in the sudden hearing loss of a diabetic patient [PDF]
The aim of our paper is to highlight the main therapeutic principles and the management options in the case of a diabetic patient who has had a sudden hearing loss.
Badiu, Dumitru Cristinel+11 more
core +3 more sources
To the Editor: Measurement of increased late-night salivary cortisol (LNSC)1 is now a mainstay in the diagnosis of endogenous Cushing syndrome (1). Patients typically sample their saliva at home and are carefully instructed to avoid using potential ...
H. Raff, Ravinder J Singh
semanticscholar +1 more source
Avenues of future research in homotransplantation of the liver with particular reference to hepatic supportive procedures, antilymphocyte serum, and tissue typing [PDF]
Three general areas of research which bear on the developing field of liver transplantation are reviewed. These are: (1) the prospects of obtaining better immunosuppression with particular reference to heterologous antilymphocyte serum; (2) the possible ...
Anderson+31 more
core +1 more source
Salivary cortisone is a potential biomarker for serum free cortisol.
CONTEXT Salivary cortisol measurement is used as a practical surrogate for serum free cortisol. However, parotid tissue harbors 11β-hydroxysteroid dehydrogenase (11β-HSD2) activity converting cortisol to cortisone.
Ilias Perogamvros+3 more
semanticscholar +1 more source
Modulation of the effectiveness of 17-alpha-hydroxy-20-beta-dihydroprogesterone or of a gonadotrophic extract on the in vitro intrafollicular maturation of oocytes of the rainbow trout Salmo gairdnerii by various non-maturing steroids [Translation from: Compte Rendu Hebdomadaire des Seances de l'Academie des Sciences, Paris, Series D 281, 811-814, 1975] [PDF]
The effectiveness of 17 α-hydroxy-20 β-dihydroprogesterone (17 α-20 β Pg) or of a trout hypophyseal gonadotrophic extract on the in vitro intrafollicular maturation of trout oocytes can be modulated by steroids which do not have a direct maturing effect;
Jalabert, B.
core
Liquid chromatography-tandem mass spectrometry - Application in the clinical laboratory [PDF]
This review provides a concise survey of liquid chromatography tandem mass spectrometry (LCTMS) as an emerging technology in clinical chemistry. The combination of two mass spectrometers with an interposed collision cell characterizes LCTMS as an ...
Ford RE+7 more
core +1 more source
Effects of intrauterine exposure to synthetic glucocorticoids on fetal, newborn, and infant hypothalamic-pituitary-adrenal axis function in humans : a systematic review [PDF]
BACKGROUND: Synthetic glucocorticoids are commonly used in reproductive medicine. Fetal organ systems are highly sensitive to changes in the intrauterine environment, including overexposure to glucocorticoids.
1994 Effect of corticosteroids for fetal maturation on perinatal outcomes+257 more
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Syndrome of apparent mineralocorticoid excess. A defect in the cortisol-cortisone shuttle.
The first adult case of 11 beta-hydroxysteroid dehydrogenase (11 beta-OHSD) deficiency is described. The impaired conversion of cortisol to cortisone (indicated by urinary cortisol and cortisone metabolites and failure to metabolize 11 alpha-[3H]cortisol
P. M. Stewart+3 more
semanticscholar +1 more source