Results 41 to 50 of about 14,615 (174)

Plasma calprotectin to assess susceptibility to bloodstream infections during paediatric acute lymphoblastic leukaemia induction treatment

British Journal of Haematology, Volume 208, Issue 4, Page 1339-1346, April 2026.
Summary Chemotherapy‐induced neutropenia, monitored by peripheral blood absolute neutrophil count (ANC), increases the risk of bloodstream infections (BSIs). However, ANC may not reflect the total neutrophil population, as it omits neutrophils at extravascular sites.
Johanna Vævest Nymann Eriksen, Silvia de Pietri, Mathias Rathe, Henrik Hasle, Christian Enevold, Claus H. Nielsen, Kjeld Schmigelow, Claus Moser, Klaus Müller, Sarah Weischendorff   +9 more
wiley   +1 more source

Whole genome sequencing revealed an outbreak of toxigenic Corynebacterium diphtheriae in Zinder region, Niger

International Journal of Infectious Diseases
Objectives: Since 2022, the Zinder region has been facing an epidemic of diphtheria. The objective of this study was to investigate the epidemiological and virulence characteristics of the diphtheria epidemic in the Zinder region.
Doutchi Mahamadou, Adamou Bara Abdoul-Aziz, Abdourahamane Yacouba, Lamine Mahaman Moustapha, Souleymane Adoum Fils, Georges Thomas Abraham, Bagnou Hamsatou, Manzo Farouk, Serge Paul Eholié, Saidou Mamadou   +9 more
doaj   +1 more source

Murine Intestinal Neonatal and Adult Dendritic Cell Subset Migration and Activation Characteristics in Response to Toll‐Like Receptor Stimulation Through MyD88

Scandinavian Journal of Immunology, Volume 103, Issue 4, April 2026.
Despite their importance, dendritic cell subsets are not well characterised in neonates. We here provide fundamental information on the abundance and phenotype of small‐intestinal neonatal DCs and assess the role of MyD88 in neonatal and adult DC migration in response to several toll‐like receptor ligands.
Konjit Getachew Muleta, Signe Holst, Agnès Garcias López, Sayoni Chakraborty, Clement da Silva, Adam F. Cunningham, Isabel Ulmert, Joy Nakawesi, Julia Hütter, Katharina Lahl   +9 more
wiley   +1 more source

Proteomics of Toxigenic Corynebacteria

Proteomes, 2023
Within the genus Corynebacterium, six species are potential carriers of the tox gene, which encodes the highly potent diphtheria exotoxin: Corynebacterium diphtheriae, Corynebacterium belfantii, Corynebacterium rouxii, Corynebacterium ulcerans ...
Andreas Burkovski
doaj   +1 more source

MODERN APPROACHES IN COMPLEX LABORATORY TESTING FOR DIPHTHERIA

Инфекция и иммунитет, 2014
. The criteria of reliable validation of population protection against diphtheria on the base of two indices including quantity of antitoxic antibodies to diphtheria and avidity index have been established.
L. A. Kraeva, E. A. Alekseeva, G. Y. Tseneva, L. A. Lipatova, G. I. Bespalova   +4 more
doaj   +1 more source

Update of the list of QPS‐recommended biological agents intentionally added to food or feeds as notified to EFSA

EFSA Journal, Volume 24, Issue 1, January 2026.
Abstract The qualified presumption of safety (QPS) process was developed to provide a harmonised safety assessment approach to support EFSA Scientific Panels and Units. The QPS approach assesses the taxonomic identity, body of relevant knowledge and safety concerns of microorganisms intentionally added to the food and feed chain.
EFSA Panel on Biological Hazards (BIOHAZ), Ana Allende, Avelino Alvarez‐Ordóñez, Valeria Bortolaia, Sara Bover‐Cid, Alessandra De Cesare, Wietske Dohmen, Laurent Guillier, Liesbeth Jacxsens, Maarten Nauta, Lapo Mughini‐Gras, Jakob Ottoson, Luisa Peixe, Fernando Perez‐Rodriguez, Panagiotis Skandamis, Elisabetta Suffredini, Marianne Chemaly, Pier Sandro Cocconcelli, Pablo Salvador Fernández Escámez, Miguel Prieto Maradona, Amparo Querol, Lolke Sijtsma, Juan Evaristo Suarez, Ingvar Sundh, Fulvio Barizzone, Justine Dastouet, Nadya Doyle, Sandra Correia, Lieve Herman   +28 more
wiley   +1 more source

Silica Nanoparticles as Multifunctional Platforms for Vaccine Delivery and Immune Modulation in Infectious Diseases

Advanced NanoBiomed Research, Volume 5, Issue 12, December 2025.
Overview of the use of silica nanoparticles in vaccines against pathogens. Different kinds of vaccines against infectious diseases are currently using solid or mesoporous silica nanoparticles in their formulation. Silica microparticles and nanoparticles (SiNPs) have been studied as vehicles for vaccines.
Noe Juvenal Mendoza‐Ramírez, Julio García‐Cordero, Gabriela Navarro‐Tovar, Leticia Cedillo‐Barrón   +3 more
wiley   +1 more source

Microevolution and genomic epidemiology of the diphtheria-causing zoonotic pathogen Corynebacterium ulcerans

Nature Communications
Corynebacterium ulcerans is an emerging zoonotic pathogen which causes diphtheria-like infections. Although C. ulcerans is found in multiple domestic and wild animal species, most human cases are linked with pets.
Chiara Crestani, Virginie Passet, Martin Rethoret-Pasty, Nora Zidane, Sylvie Brémont, Edgar Badell, Alexis Criscuolo, Sylvain Brisse   +7 more
doaj   +1 more source

Tox-positive Corynebacterium ulcerans in hedgehogs, Germany

Emerging Microbes and Infections, 2019
Toxigenic Corynebacterium ulcerans may cause both respiratory and cutaneous diphtheria in humans. As a zoonotic emerging pathogen it has been isolated from a wide variety of animals living in captivity, such as livestock, pet, zoo and research animals ...
Anja Berger, Alexandra Dangel, Martin Peters, Kristin Mühldorfer, Silke Braune, Tobias Eisenberg, Claudia A. Szentiks, Jörg Rau, Regina Konrad, Stefan Hörmansdorfer, Nikolaus Ackermann, Andreas Sing   +11 more
doaj   +1 more source

Development and Validation of a High‐Throughput Screening Assay for the Legionella ADP‐Ribosyl Transferase SdeA

ChemBioChem, Volume 26, Issue 21, November 8, 2025.
We show the optimization and application of a fluorogenic assay to monitor Legionella SdeA activity in a High‐Throughput‐Screening campaign. Ubiquitination of proteins is one of the most crucial post‐translational modifications in eukaryotic cells, typically involving conjugation of ubiquitin to a lysine residue in a substrate using a three‐enzyme ...
Halana C. Vlaming, Vito Pol, Bjorn R. van Doodewaerd, Angeliki Moutsiopoulou, Paul P. Geurink, Robbert Q. Kim, Gerbrand J. van der Heden van Noort   +6 more
wiley   +1 more source