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Corynebacterium diphtheriae (C. diphtheriae) is the causative agent of diphtheria. The main virulence factor of C. diphtheriae is diphtheria toxin, which is encoded by the tox gene and regulated by the dtxR gene.
Vivi Setiawaty +11 more
doaj +1 more source
Corynebacterium diphtheriae [PDF]
Corynebacterium diphtheriae was first observed by Klebs in 1883 and was cultivated a year later by Loeffler, whose description in 1884 of the causative organism of diphtheria remains a standard. Diphtheria was a life-threatening disease throughout the world until the therapeutic use of antitoxin and the use, as a public health measure, of childhood ...
openaire +1 more source
Novel Clinical Monitoring Approaches for Reemergence of Diphtheria Myocarditis, Vietnam
Diphtheria is a life-threatening, vaccine-preventable disease caused by toxigenic Corynebacterium bacterial species that continues to cause substantial disease and death worldwide, particularly in vulnerable populations.
Ho Quang Chanh +7 more
doaj +1 more source
This review highlights recent advances in ZnO nanocrystals, including fabrication methods, characterization techniques, and their emerging photocatalytic and biomedical applications, while discussing current challenges and future research opportunities.
Amir Zada, Shohreh Azizi
wiley +1 more source
Characterization of the biotin uptake system encoded by the biotin-inducible bioYMN operon of Corynebacterium glutamicum [PDF]
Schneider J, Peters-Wendisch P, Stansen KC, et al. Characterization of the biotin uptake system encoded by the biotin-inducible bioYMN operon of Corynebacterium glutamicum. BMC Microbiology.
Götker Susanne +20 more
core +1 more source
Re-emergence of Corynebacterium diphtheriae [PDF]
Diphtheria is re-emerging in Europe. A total of 36 cases were reported in Europe in 2015 versus 53 cases between 2000 and 2009.We report two cases of Corynebacterium diphtheriae infection in a French hospital in 2016: a cutaneous infection with negative toxin testing in a French traveller, and a respiratory diphtheria carriage with positive toxin ...
Scheifer, Carole +8 more
openaire +3 more sources
This study explores the interaction between Diphtheria Toxin (DT) and Bcl‐2 in HT‐29 cells. Integrating molecular docking with gene expression analysis, we demonstrate DT's high‐affinity binding to Bcl‐2 and a significant downregulation of BCL2 mRNA. These findings suggest that DT modulates anti‐apoptotic pathways, influencing colorectal cancer cell ...
Elif Ercan +3 more
wiley +1 more source
Diphtheria vaccination coverage among Nigerian children remains suboptimal (56%). Coverage is significantly lower in Northern states and inversely correlated with multidimensional poverty. Addressing poverty‐related deprivations is essential to improving immunization equity and curbing recurrent diphtheria outbreaks.
Olufemi Olulaja, Rana Jaber
wiley +1 more source
Summary Chemotherapy‐induced neutropenia, monitored by peripheral blood absolute neutrophil count (ANC), increases the risk of bloodstream infections (BSIs). However, ANC may not reflect the total neutrophil population, as it omits neutrophils at extravascular sites.
Johanna Vævest Nymann Eriksen +9 more
wiley +1 more source
Objectives: Since 2022, the Zinder region has been facing an epidemic of diphtheria. The objective of this study was to investigate the epidemiological and virulence characteristics of the diphtheria epidemic in the Zinder region.
Doutchi Mahamadou +9 more
doaj +1 more source

