Results 61 to 70 of about 43,628 (243)

Sequence Analysis of Toxin Gene–Bearing Corynebacterium diphtheriae Strains, Australia

Emerging Infectious Diseases, 2017
By conducting a molecular characterization of Corynebacterium diphtheriae strains in Australia, we identified novel sequences, nonfunctional toxin genes, and 5 recent cases of toxigenic cutaneous diphtheria.
Christine J. Doyle, Adam Mazins, Rikki M.A. Graham, Ning-Xia Fang, Helen V. Smith, Amy V. Jennison   +5 more
doaj   +1 more source

Proteome Analysis of Corynebacterium diphtheriae–Macrophage Interaction

PROTEOMICS, EarlyView.
ABSTRACT Contact of Corynebacterium diphtheriae with macrophages induces adaptations on both bacterial and cellular sides. The study presented here was aiming to shed light on the simultaneous intracellular adaptation of the bacteria and changes in the proteome of the phagocytes in response to the internalization of C. diphtheriae.
Luca Musella, Jens Möller, Christopher Lischer, Julio Vera‐Gonzalez, Jörg Hofmann, Lisa Ott, Andreas Burkovski   +6 more
wiley   +1 more source

Microbiome and Metaproteome of Craniofacial Implant Regions in Health and Disease

Oral Diseases, EarlyView.
ABSTRACT Background Craniofacial defects from cancer surgery led to functional, aesthetic, and psychological challenges. Rehabilitation with craniofacial implants addresses these issues by improving prosthesis retention through osseointegration and providing predictable cosmetic results. However, maintaining a healthy transcutaneous region is essential
Daniela Lattuf Cortizo, Renato C. V. Casarin, Hélvis E. S. Paz, Camila S. Stolf, Mabelle F. Monteiro, Mônica T. V. Labate, Márcio Z. Casati, Luciano Lauria Dib   +7 more
wiley   +1 more source

Impact of NLRP1 Met1154Val and IL1B variants on gestational malaria: an unexplored role of NLRP1 in inflammasome activation by Plasmodium spp.

The Journal of Pathology, Volume 267, Issue 3, Page 304-314, November 2025.
Abstract We hypothesized that variants in inflammasome‐related genes could influence susceptibility to gestational malaria (GM). To test this, we conducted an association study in a cohort of pregnant women from a malaria‐endemic region in northern Brazil, assessing whether specific functional single nucleotide variants (SNVs) in inflammasome genes ...
Vinicius NC Leal, Jessica A Ribeiro, Leticia Girardi Marra, Alexandre TT Rio, Edione C Reis, Gerhard Wunderlich, Jamille G Dombrowski, Claudio RF Marinho, Alessandra Pontillo   +8 more
wiley   +1 more source

Polyanhydride‐Based Microparticles for Programmable Pulsatile Release of Diphtheria Toxoid (DT) for Single‐Injection Self‐Boosting Vaccines

Advanced Materials, Volume 37, Issue 32, August 14, 2025.
This study presents a polyanhydride‐based delivery platform for single‐injection, self‐boosting vaccines. The system enables programmable, pulsatile release of diphtheria toxoid with high antigen recovery and is guided by machine learning for tunability. In vivo results show immune responses comparable to multi‐dose regimens, highlighting its potential
Linzixuan Zhang, Ruiqing Xiao, Wenhao Gao, Johnny Garcia, Xinyan Pan, John L. Daristotle, Timothy Forster, Jooli Han, Mehr Chaddah, Dhruv Varshney, Nandita Menon, Kevin J. McHugh, Benjamin J. Pedretti, Jing Ying Yeo, Xin Yang, Sydney MacDonald, Robert Langer, Ana Jaklenec   +17 more
wiley   +1 more source

Cutaneous Corynebacterium Infection Presenting with Disseminated Skin Nodules and Ulceration

Case Reports in Dermatology, 2017
In the context of the European migrant crisis, more and more cases of cutaneous diphtheria are seen. A typical presentation includes painful cutaneous ulcerations with grayish-whitish pseudomembranes.
Antonios G.A. Kolios, Antonio Cozzio, Annelies S. Zinkernagel, Lars E. French, Thomas M. Kündig   +4 more
doaj   +1 more source

Detection of toxin-producing Corynebacterium diphtheriae from throat swabs of diphtheria patients using duplex real-time PCR

Iranian Journal of Microbiology, 2020
Background and Objectives: Diphtheria is a potentially fatal disease caused by toxigenic bacterial infection, particularly from Corynebacterium diphtheriae (C. diphtheriae). Isolation of C.
Yeva Rosana, Luh Inta Prilandari, Ruhsyahadati Ajisman, T. Hartono, A. Yasmon   +4 more
semanticscholar   +1 more source

The Different Types of Corynebacterium diphtheria [PDF]

Journal of Hygiene, 1933
In 1890 Klein described two types of colony of the diphtheria bacillus on gelatin; one smooth and circular, the other radiating and resembling a daisy. Cowan (1927) observed two types of colony, but one of the types was thought to be due to roughening. Parker (1928) observed three types of colony, some of which were considered ordinary rough variants.
W. H. Fussell, T. V. Cooper, J. Menton, F. W. Duke   +3 more
openaire   +3 more sources

Phage‐mediated horizontal transfer of Salmonella enterica virulence genes with regulatory feedback from the host

iMeta, Volume 4, Issue 4, August 2025.
In this study, we found evidence of phage‐mediated horizontal transfer of virulence genes in Salmonella enterica in global habitats from a molecular evolutionary perspective. Notably, csrA, a global regulator in Salmonella enterica, curbed horizontal gene transfer by inhibiting the cyclization and release of prophage.
Tianjing She, Demeng Tan, Jose Luis Balcazar, Ville‐Petri Friman, Danrui Wang, Dong Zhu, Mao Ye, Mingming Sun, Shujian Yuan, Feng Hu   +9 more
wiley   +1 more source

Severe Pneumonia Caused by Toxigenic Corynebacterium ulcerans Infection, Japan

Emerging Infectious Diseases, 2018
Corynebacterium ulcerans infection was recently recognized as a zoonosis. We present 2 cases of severe pneumonia complicated by diffuse pseudomembrane formation on the bronchus caused by C. ulcerans–producing diphtheria toxin.
Ikkoh Yasuda, Hisayo Matsuyama, Tomoko Ishifuji, Yoshiro Yamashita, Masahiro Takaki, Konosuke Morimoto, Motohiro Sekino, Katsunori Yanagihara, Tatsuya Fujii, Masaaki Iwaki, Akihiko Yamamoto, Koya Ariyoshi, Takeshi Tanaka   +12 more
doaj   +1 more source