Results 91 to 100 of about 39,594 (255)

Synthesis of Bioorthogonal Mycolic Acids: Chemoselective Reduction of β‐Ketoesters Containing an Alkyne Using the Noyori Catalyst

European Journal of Organic Chemistry, Volume 28, Issue 41, November 17, 2025.
Bioorthogonal mycolic acids that are suitable probes for the study of the cell envelope of mycobacteria are synthesized by Noyori reduction of β‐ketoesters featuring a protected terminal alkyne. The triisopropylsilyl group is found to be very efficient in preventing the reduction of the alkyne.
Paulin Rollando, Emilie Lesur, Dominique Urban, Gilles Doisneau, Dominique Guianvarc'h, Yann Bourdreux   +5 more
wiley   +1 more source

Mapping the ultrastructural topology of the corynebacterial cell surface.

PLoS Biology
Corynebacterium glutamicum is a diderm bacterium extensively used in the industrial-scale production of amino acids. Corynebacteria belong to the bacterial family Mycobacteriaceae, which is characterized by a highly unusual cell envelope with an outer ...
Buse Isbilir, Anna Yeates, Vikram Alva, Tanmay A M Bharat   +3 more
doaj   +1 more source

Real Time Monitoring of NADPH Concentrations in Corynebacterium glutamicum and Escherichia coli via the Genetically Encoded Sensor mBFP

Frontiers in Microbiology, 2018
Analyses of intracellular NADPH concentrations are prerequisites for the design of microbial production strains and process optimization. mBFP was described as metagenomics derived, blue fluorescent protein showing NADPH-dependent fluorescence ...
Oliver Goldbeck, Alexander W. Eck, Gerd M. Seibold, Gerd M. Seibold   +3 more
doaj   +1 more source

A Genetically Encoded Biosensor for Characterizing Transport and Metabolism of Glutarate

Advanced Science, Volume 12, Issue 42, November 13, 2025.
Here, a genetically encoded glutarate biosensor, Glusor, is developed based on transcriptional regulator CsiR. Glusor can quantify glutarate concentrations with good accuracy and precision. Then, the role of KgtP and YnfM are identified and characterized by using Glusor. Glusor also allows glutarate spatiotemporal resolution in live cells, facilitating
Kaiyu Gao, Hui Zhang, Yidong Liu, Xianzhi Xu, Wei Liu, Zhaoqi Kang, Rong Xu, Shuang Hou, Ping Han, Chuanjuan Lü, Cuiqing Ma, Ping Xu, Chao Gao   +12 more
wiley   +1 more source

Corynebacterium glutamicum as platform for the production of hydroxybenzoic acids

Microbial Cell Factories, 2018
BackgroundHydroxybenzoic acids are industrially relevant aromatic compounds, which also play key roles in the microbial carbon metabolism, e.g., as precursors for the synthesis of cofactors or metal-chelating molecules.
Nicolai Kallscheuer, Jan Marienhagen
semanticscholar   +1 more source

Bioactive Compounds Derived From Natural Foods Against Metabolic Syndrome and the Advances of Resveratrol and Caffeic Acid in Microbial Cell Factory Production: A Review

Food Frontiers, Volume 6, Issue 6, Page 2575-2590, November 2025.
Metabolic syndrome is characterized by abdominal obesity, hyperglycemia, dyslipidemia, and hypertension. Bioactive compounds extracted from herbs, tea, and coffee using microbial cell factories, particularly resveratrol and caffeic acid, have demonstrated remarkable potential in the management of metabolic syndrome, offering innovative solutions for ...
Tao Li, Jingjing Shi, Tao Liu, Chongxiang Xue, Lin Han, Mingzhe Zhang, Linhua Zhao, Xiaolin Tong   +7 more
wiley   +1 more source

Studies on activities of PTA, AK, ICL and MS enzymes involved in the acetate metabolism of Corynebacterium glutamicum

浙江大学学报. 农业与生命科学版, 2003
The four enzymes of acetate kinase (AK), phosphotransacetylase (PTA), isocitrate lyase (ICL) and malate systhase (MS) which are involved in the acetate metabolism of Corynebacterium glutamicum have been developed in their assay methods.
RUAN Hong, XUAN Ri-rong
doaj   +1 more source

Lactiplantibacillus plantarum Attenuates Diet‐Induced Obesity and Insulin Resistance Through Gut Microbiota‐Driven PPAR/PI3K‐Axis Modulation

Microbial Biotechnology, Volume 18, Issue 11, November 2025.
Lactobacillus plantarum LPPerfectus001 (LPPH) reduced weight and fat, improved insulin sensitivity and normalised lipids in high‐fat/fructose‐fed rats without altering energy intake. It restored gut microbiota (↑Akkermansia, ↓pathogens), elevated SCFAs and modulated adipose, liver and muscle metabolism via PPAR, PI3K‐Akt and AMPK pathways ...
Yecheng Gao, Anqi Zhu, Jingjin Li, Hualin Liu, Xiaomin Li, Heping Zhang   +5 more
wiley   +1 more source

Vanillin production by Corynebacterium glutamicum using heterologous aromatic carboxylic acid reductases

Biotechnology for Biofuels and Bioproducts
Background Vanillin is a flavoring substance derived from vanilla. We are currently developing a biotransformation method for vanillin production using glucose.
Miku Matsuzawa, Junko Ito, Keiko Danjo, Keita Fukui   +3 more
doaj   +1 more source

Nutritional properties of pilot-scale manufactured single-cell proteins from a Corynebacterium glutamicum

CyTA - Journal of Food
Single-cell proteins (SCPs) derived from microorganisms are sustainable and standard-manufacturable protein sources. Corynebacterium glutamicum is one of the prospective bacteria for SCP production. To evaluate nutritional properties of C. glutamicum-SCP,
Sehyeon Park, Taeyeon Kim, Soyeon Lee, Seungki Lee, Pil Kim   +4 more
doaj   +1 more source