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Handbook of Corynebacterium glutamicum
2005Part I: History A Short History of the Birth of the Amino Acid Industry in Japan, S. Kinoshita Part II: Taxonomy Corynebacterium Taxonomy, W. Liebl Part III: Genome, Plasmids and Gene Expression The Genomes of Amino Acid-producing Corynebacteria, J. Kalinowski Native Plasmids of Amino Acid-producing Corynebacteria, A.
Michael Bott, Lothar Eggeling
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A transketolase mutant of Corynebacterium glutamicum
Applied Microbiology and Biotechnology, 1998A transketolase mutant was first isolated from Corynebacterium glutamicum, an organism of industrial importance. The mutant strain exhibited an absolute requirement for shikimic acid or the aromatic amino acids and vitamins for growth, and also failed to grow on ribose or gluconic acid as sole carbon source, even with the aromatic supplement.
Masato Ikeda +2 more
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Protein secretion inCorynebacterium glutamicum
Critical Reviews in Biotechnology, 2016Corynebacterium glutamicum, a Gram-positive bacterium, has been widely used for the industrial production of amino acids, such as glutamate and lysine, for decades. Due to several characteristics - its ability to secrete properly folded and functional target proteins into culture broth, its low levels of endogenous extracellular proteins and its lack ...
Zhonghu Bai +5 more
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Biorefinery Applications of Corynebacterium glutamicum
2012The biorefinery concept is an emerging concept for conducting industrial processes to manufacture a range of commodity chemicals, fuels, and energy from biomass-based feedstock. The current interest in implementing a biorefinery industry is largely derived by a combination of rising petroleum prices as well as the need to reduce greenhouse gas ...
Toru Jojima +2 more
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Importance of mycoloyltransferases on the physiology of Corynebacterium glutamicum
Microbiology, 2004Mycoloyltransferases (Myts) play an essential role in the biogenesis of the cell envelope of members of the Corynebacterineae, a group of bacteria that includes the mycobacteria and corynebacteria. While the existence of several functional myt genes has been demonstrated in both mycobacteria and corynebacteria (cmyt), the disruption of any of these ...
Marielle Tropis +8 more
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Engineering Corynebacterium glutamicum for the production of pyruvate
Applied Microbiology and Biotechnology, 2012A Corynebacterium glutamicum strain with inactivated pyruvate dehydrogenase complex and a deletion of the gene encoding the pyruvate:quinone oxidoreductase produces about 19 mM L: -valine, 28 mM L: -alanine and about 55 mM pyruvate from 150 mM glucose. Based on this double mutant C. glutamicum △aceE △pqo, we engineered C.
Bernhard J. Eikmanns +2 more
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Sigma factors and promoters in Corynebacterium glutamicum
Journal of Biotechnology, 2011The Corynebacterium glutamicum genome codes for 7 sigma subunits (factors) of RNA polymerase (RNAP): primary sigma factor SigA (σ(A)), primary-like SigB and 5 other alternative sigma factors (SigC, SigD, SigE, SigH and SigM). Each sigma factor is responsible for recognizing promoters of genes belonging to a regulon (sigmulon) involved in specific ...
Miroslav Pátek, Jan Nešvera
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Synthetic promoter libraries for Corynebacterium glutamicum
Applied Microbiology and Biotechnology, 2014The ability to modulate gene expression is an important genetic tool in systems biology and biotechnology. Here, we demonstrate that a previously published easy and fast PCR-based method for modulating gene expression in lactic acid bacteria is also applicable to Corynebacterium glutamicum.
Peter Ruhdal Jensen +5 more
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Identifizierung von Promotoren in Corynebacterium glutamicum
BIOspektrum, 2014The high-throughput sequencing of cDNA derived from whole transcript — omes (RNA-Seq) has revolutionized studies of bacterial transcription. We optimized and applied RNA-Seq for the genome-wide determination of transcription starts and their associated promoters using as an example of the biotechnologically relevant microorganism Corynebacterium ...
Busche, Tobias +3 more
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Genome Engineering of Corynebacterium glutamicum
2012As a direct consequence of the recent advances in DNA sequencing technologies, complete genome sequences of more than 1,200 bacterial species have already been deciphered and they form an important resource for understanding the diversity of bacterial metabolic systems.
Masayuki Inui, Nobuaki Suzuki
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