Results 211 to 220 of about 50,392 (258)

Emerging Corynebacterium glutamicum systems biology

Journal of Biotechnology, 2006
Corynebacterium glutamicum is widely used for the biotechnological production of amino acids. Amino acid producing strains have been improved classically by mutagenesis and screening as well as in a rational manner using recombinant DNA technology. Metabolic flux analysis may be viewed as the first systems approach to C.
Wendisch, Volker F., Bott, M., Kalinowski, Jörn, Oldiges, M., Wiechert, W.   +4 more
openaire   +2 more sources

Vanillate Metabolism in Corynebacterium glutamicum

Current Microbiology, 2005
Corynebacterium glutamicum, a Gram-positive soil bacterium belonging to the mycolic acids-containing actinomycetes, is able to use the lignin degradation products ferulate, vanillate, and protocatechuate as sole carbon sources. The gene cluster responsible for vanillate catabolism was identified and characterized.
Hedda, Merkens, Gabriele, Beckers, Astrid, Wirtz, Andreas, Burkovski   +3 more
openaire   +2 more sources

Fermentative High-Level Production of 5-Hydroxyvaleric Acid by Metabolically Engineered Corynebacterium glutamicum

, 2021
We report metabolic engineering of Corynebacterium glutamicum (C. glutamicum) for high-level production of 5-hydroxyvaleric acid (5-HV), an important C5 platform chemical covering a wide range of i...
Y. Sohn, Minsoo Kang, Kei-Anne Baritugo, J. Son., K. Kang, M. Ryu, S. Lee, Mingi Sohn, Ye Jean Jung, Kyungmoon Park, Si Jae Park, J. Joo, H. Kim   +12 more
semanticscholar   +1 more source

Proteome analysis ofCorynebacterium glutamicum

ELECTROPHORESIS, 2001
By the use of different Corynebacterium glutamicum strains more than 1.4 million tons of amino acids, mainly L-glutamate and L-lysine, are produced per year. A project was started recently to elucidate the complete DNA sequence of this bacterium. In this communication we describe an approach to analyze the C.
Hermann, T., Pfefferle, W., Baumann, C., Busker, E., Schaffer, S., Bott, M., Sahm, H., Dusch, N., Kalinowski, Jörn, Pühler, Alfred, Bendt, A. K., Kramer, R., Burkovski, A.   +12 more
openaire   +3 more sources

The respiratory chain of Corynebacterium glutamicum

Journal of Biotechnology, 2003
Corynebacterium glutamicum is an aerobic bacterium that requires oxygen as exogenous electron acceptor for respiration. Recent molecular and biochemical analyses together with information obtained from the genome sequence showed that C. glutamicum possesses a branched electron transport chain to oxygen with some remarkable features.
Michael, Bott, Axel, Niebisch
openaire   +2 more sources

Ethanol catabolism in Corynebacterium glutamicum.

Journal of molecular microbiology and biotechnology, 2008
Corynebacterium glutamicum grows on a variety of carbohydrates and organic acids as single or combined sources of carbon and energy. Here we show the ability of C. glutamicum to grow on ethanol with growth rates up to 0.24 h(-1) and biomass yields up to 0.47 g dry weight (g ethanol)(-1). Mutants of C. glutamicum deficient in phosphotransacetylase (PTA),
Arndt, A., Auchter, M., Ishige, T., Wendisch, Volker F., Eikmanns, B. J.   +4 more
openaire   +2 more sources

Drug Extrusion in Corynebacterium Glutamicum

Microbial Drug Resistance, 1997
ABSTRACT We selected a mutant of Corynebacterium glutamicum , EB R , which can grow in a medium containing cytotoxic ethidium bromide (EtBr) at a high concentration of 100 μM.
K, Kaidoh, M, Kimura, S, Miyauchi, T, Nara, N, Kamo   +4 more
openaire   +2 more sources

Engineering Corynebacterium glutamicum for high-titer biosynthesis of hyaluronic acid.

Metabolic Engineering, 2019
Hyaluronic acid (HA) is a member of the glycosaminoglycan family and has been widely used in clinical, medical, cosmetic and food industries. In this study, we constructed a superior cell factory in Corynebacterium glutamicum for high-titer HA ...
Fangyu Cheng, Huimin Yu, G. Stephanopoulos   +2 more
semanticscholar   +1 more source

Glycerol-3-phosphatase of Corynebacterium glutamicum

Journal of Biotechnology, 2012
Formation of glycerol as by-product of amino acid production by Corynebacterium glutamicum has been observed under certain conditions, but the enzyme(s) involved in its synthesis from glycerol-3-phosphate were not known. It was shown here that cg1700 encodes an enzyme active as a glycerol-3-phosphatase (GPP) hydrolyzing glycerol-3-phosphate to ...
Lindner, Steffen, Meiswinkel, Tobias, Panhorst, Maren, Youn, Jung-Won, Wiefel, Lars, Wendisch, Volker F.   +5 more
openaire   +2 more sources

Synthetic promoter libraries for Corynebacterium glutamicum

Applied Microbiology and Biotechnology, 2014
The ability to modulate gene expression is an important genetic tool in systems biology and biotechnology. Here, we demonstrate that a previously published easy and fast PCR-based method for modulating gene expression in lactic acid bacteria is also applicable to Corynebacterium glutamicum.
Jakob Vang, Rytter, Søren, Helmark, Jun, Chen, Mateusz Jakub, Lezyk, Christian, Solem, Peter Ruhdal, Jensen   +5 more
openaire   +2 more sources