Results 41 to 50 of about 44,270 (153)
Dynapenia and Sarcopenia as Risk Factors for Mortality in Interstitial Lung Disease
Respirology, Volume 30, Issue 5, Page 424-434, May 2025.ILD patients had a higher prevalence of body composition alterations, among them dynapenia and sarcopenia; these are independent risks for mortality. Pulmonary rehabilitation, including nutritional treatment, should be part of the routine management of this population to improve nutritional status and delay the skeletal muscle disorder.Alan Aldair Ibarra‐Fernández, Robinson Robles‐Hernández, Arturo Orea‐Tejeda, Dulce González‐Islas, Angelia Jiménez‐Valentín, Rocío Sánchez‐Santillán, Laura Patricia Arcos‐Pacheco, Emilio Gutiérrez‐Luna, Andrea Zurita‐Sandoval, Tomas Peña‐Espinosa, Rosaura Gutiérrez‐Vargas, Laura Flores‐Cisneros +11 morewiley +1 more sourceClinical Characteristics of Anti‐Synthetase Syndrome: Analysis From the Classification Criteria for Anti‐Synthetase Syndrome Project
Arthritis &Rheumatology, Volume 77, Issue 4, Page 477-489, April 2025.Objective
Anti‐synthetase syndrome (ASSD) is a rare systemic autoimmune rheumatic disease (SARD) with significant heterogeneity and no shared classification criteria. We aimed to identify clinical and serological features associated with ASSD that may be suitable for inclusion in the data‐driven classification criteria for ASSD. Methods
We used a large,Sara Faghihi‐Kashani, Akira Yoshida, Francisca Bozan, Giovanni Zanframundo, Davide Rozza, Aravinthan Loganathan, Eduardo Dourado, Gianluca Sambataro, Iazsmin Bauer‐Ventura, Sangmee Sharon Bae, Darosa Lim, Daphne Rivero‐Gallegos, Yasuhiko Yamano, Albert Selva‐O'Callaghan, Andrew L. Mammen, Carlo A. Scirè, Carlomaurizio Montecucco, Chester V. Oddis, David Fiorentino, Francesco Bonella, Frederick W. Miller, Ingrid E. Lundberg, Jens Schmidt, Jorge Rojas‐Serrano, Marie Hudson, Masataka Kuwana, Miguel Angel González‐Gay, Neil McHugh, Tamera J. Corte, Tracy Jennifer Doyle, Victoria P. Werth, Latika Gupta, Diana Isabel Perez Roman, Lorenzo M. Bianchessi, Phani Kumar Devarasetti, Samuel Katsuyuki Shinjo, Fabrizio Luppi, Ilaria Cavazzana, Siamak Moghadam‐Kia, Marco Fornaro, Elizabeth R. Volkmann, Matteo Piga, Jesus Loarce‐Martos, Giacomo De Luca, Johannes Knitza, Veronica Wolff‐Cecchi, Marco Sebastiani, Adam Schiffenbauer, Lisa G. Rider, Raquel Campanilho‐Marques, Lucian Marts, Elena Bravi, Harsha Gunawardena, Rohit Aggarwal, Lorenzo Cavagna, on behalf of the Classification Criteria for Anti‐Synthetase Syndrome Project participating investigators, Anamika Anuja, Domenico Sambataro, Michele Colaci, Carlo Vancheri, Mayra Mejia, Pedro Abisay Rivera Matias, Francesca Bottazzi, Claudia Alpini, Liza Rajasekhar, Vikas Agarwal, Fernando Henrique Carlos De Souza, Renata Miossi, Maria Rosa Pozzi, Paola Faverio, Giovanni Franco, Giulia Dei, Franco Franceschini, David Lacomis, Florenzo Iannone, Francesco Girolamo, Ernesto Trallero‐Araguás, Albert Gil‐Vila, Ana Villar, Christina Charles‐Schoeman, Heather Bukiri, Chiara Murru, Alberto Cauli, Javier Bachiller‐Corral, Lorenzo Dagna, Corrado Campochiaro, Jorg Distler, George Schett, Matias Florenzano, Felipe Reyes, Antony Amato, Paul Dellaripa, Silvana Saavedra, Karen Vergara, Andreina Manfredi, Caterina Vacchi, Teresa Melo, Prateek Gandiga, Dhruv Amratia, Eugenio Arrigoni, Yuko Kaneko, Konstantinos Triantafyllias, Anna Mandel, Santos Castañeda, Esther Francisca Vicente‐Rabaneda, Océane Landon‐Cardinal, María Laura Alberti, Fabian Caro, Martín Gerardo Greco Merino, Iñigo Rua‐Figueroa, Christoph Fiehn, Jutta Bauhammer, Yair Molad, Osnat Klein, Marcello Govoni, Ran Nakashima, Erkan Alpsoy, Alain Meyer, Margherita Giannini, Hector Chinoy, James Lilleker, Laure Gallay, Vincent Cottin, Philippe Dieudè, Julien Campagne, André Pinto Saraiva, Edoardo Conticini, Giandomenco Sebastiani, Laura Nuno, Salvatore Scarpato, Elena Schiopu, Pier Paolo Sainaghi, Vega Jovani, Simone Barsotti, Natsuka Umezawa, Merrilee Needham, Giovanni Cagnotto, Maria Giovanna Danieli, Paola Tomietto, Nair Perez Gomez, Massimiliano Limonta, Giovanni Barausse, Yasuhiro Kondo, Daniela Ghetie, Farah Tamirou, Pari Basharat, Stylianos Tomaras, Reinhard Edmund Voll, Helena Andersson, Julia Martinez Barrio, Matthias Schneider, Paola Parronchi, Antonella Notarnicola, Jose Cifrian +153 morewiley +1 more sourceEnhancing quality of life in severe post-COVID-19 survivors through multidisciplinary care
ERJ Open ResearchBackground
COVID-19 survivors who were hospitalised continue to experience long-term multisystemic sequelae and symptoms, impacting their health-related quality of life (HRQoL).Daniela Josefina Cataneo-Piña, Armando Castorena-Maldonado, Dulce González-Islas, Susana Galicia-Amor, Arturo Orea-Tejeda, Viridiana Pelaez-Hernández, Alma Delia Gutiérrez-Álvarez, Jorge Rojas-Serrano, Eduardo Ortiz-Reyes, Aline Mendoza-Méndez, Ángel Mendoza-Escamilla, Sinuhe Fabre-Alonso, Ivette Buendía-Roldán, Laura Gochicoa-Rangel, Carlos López-García, Marian Radillo-Gil, Celia Gabriela Hernández Favela, Sergio Monraz-Perez, Jorge Salas-Hernández, Patricio Santillán-Doherty +19 moredoaj +1 more sourceOPG and BAFF as predictive biomarkers of the severity of SARS‐CoV‐2 infection
Journal of Cellular and Molecular Medicine, Volume 29, Issue 3, February 2025.Abstract
Molecules of the tumour necrosis factor superfamily (TNFSF) are key players in immune regulation; an increase in some TNFSF molecules has been reported during severe COVID‐19. In this study, we profiled and evaluated TNFSF members in the serum of COVID‐19 vaccine‐naïve patients to identify potential biomarkers associated with disease severity. Andy Ruiz, Carlos Peña‐Bates, Lucero A. Ramon‐Luing, Daniel Baca‐Nuñez, Marco Antonio Vargas, Karen Medina‐Quero, Neptali Gutierrez, Joel A. Vázquez‐Pérez, Ramcés Falfán‐Valencia, Gloria Pérez‐Rubio, Carolina Di Benedetto, Ivette Buendia‐Roldan, Moisés Selman, Paola Betancur, Leslie Chavez‐Galan +14 morewiley +1 more sourceGlycine by enteral route does not improve major clinical outcomes in severe COVID-19: a randomized clinical pilot trial
Scientific ReportsThere is a worrying scarcity of drug options for patients with severe COVID-19. Glycine possesses anti-inflammatory, cytoprotective, endothelium-protective, and platelet-antiaggregant properties, so its use in these patients seems promising. In this open Mario H. Vargas, Jaime Chávez, Rosangela Del-Razo-Rodríguez, Carolina Muñoz-Perea, Karina Julieta Romo-Domínguez, Renata Báez-Saldaña, Uriel Rumbo-Nava, Selene Guerrero-Zúñiga +7 moredoaj +1 more sourceThe impact of circulating nucleosomes on inflammation in acute lung injury
The FASEB Journal, Volume 38, Issue 23, 15 December 2024.Extracellular histones are predominantly released as nucleosomes during ALI. Extracellular nucleosomes can lead to macrophage activation and trigger inflammation in various organs. Mechanistically, nucleosomes activate the NF‐κB signaling pathway, while inhibition of NF‐κB by sulfasalazine attenuated nucleosome‐induced macrophage activation.Saugata Dutta, Yin Zhu, Sultan Almuntashiri, Payaningal R. Somanath, Shaheen Islam, Wenbo Zhi, Gustavo Ramírez, Nora Regino, María Jose Leyva‐Zilli, Victoria Muñoz‐Guido, Luis Jiménez‐Alvarez, Alfredo Cruz‐Lagunas, Tatiana S. Rodriguez‐Reyna, Joaquin Zuñiga, Xiaoyun Wang, Duo Zhang +15 morewiley +1 more source