Results 41 to 50 of about 44,270 (153)

The Direct and Individual Transcriptional Function of the Human Homodimeric and Heterodimeric Basic Helix–Loop–Helix Transcription Factors E47 and Scleraxis

open access: yesThe FASEB Journal, Volume 39, Issue 12, 30 June 2025.
The isolated yeast model allowed visualization of the function of the heterodimeric SCX and E47 transcription factors (TFs) in the absence of other interacting proteins. The findings support the need for additional transcription factor binding sites (TFBS) and a permissive chromatin landscape for these TFs to exert a positive transcriptional effect ...
Karla Miranda López‐Delucio   +5 more
wiley   +1 more source

Dynapenia and Sarcopenia as Risk Factors for Mortality in Interstitial Lung Disease

open access: yesRespirology, Volume 30, Issue 5, Page 424-434, May 2025.
ILD patients had a higher prevalence of body composition alterations, among them dynapenia and sarcopenia; these are independent risks for mortality. Pulmonary rehabilitation, including nutritional treatment, should be part of the routine management of this population to improve nutritional status and delay the skeletal muscle disorder.
Alan Aldair Ibarra‐Fernández   +11 more
wiley   +1 more source

Clinical Characteristics of Anti‐Synthetase Syndrome: Analysis From the Classification Criteria for Anti‐Synthetase Syndrome Project

open access: yesArthritis &Rheumatology, Volume 77, Issue 4, Page 477-489, April 2025.
Objective Anti‐synthetase syndrome (ASSD) is a rare systemic autoimmune rheumatic disease (SARD) with significant heterogeneity and no shared classification criteria. We aimed to identify clinical and serological features associated with ASSD that may be suitable for inclusion in the data‐driven classification criteria for ASSD. Methods We used a large,
Sara Faghihi‐Kashani   +153 more
wiley   +1 more source

Enhancing quality of life in severe post-COVID-19 survivors through multidisciplinary care

open access: yesERJ Open Research
Background COVID-19 survivors who were hospitalised continue to experience long-term multisystemic sequelae and symptoms, impacting their health-related quality of life (HRQoL).
Daniela Josefina Cataneo-Piña   +19 more
doaj   +1 more source

El mito de la riqueza de México variaciones sobre un tema de Cosío Villegas

open access: yes, 2003
THIS ESSAY DEALS WITH THE MISCONCEPTION OF MEXICAN TERRITORY AS A HORN OF PLENTY OR CORNUCOPIA. IN OTHER WORDS, WE TRACE THE ORIGINS OF DANIEL COSIO VILLEGAS' IDEA ABOUT "THE LEGENDARY WEALTH OF MEXICO".
Pedro Salmerón Sanginés
semanticscholar   +1 more source

Cosío Villegas, historiador

open access: yesHistoria Mexicana El Colegio de México, 1954
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Silvio Zavala, José Fuentes Mares
doaj  

OPG and BAFF as predictive biomarkers of the severity of SARS‐CoV‐2 infection

open access: yesJournal of Cellular and Molecular Medicine, Volume 29, Issue 3, February 2025.
Abstract Molecules of the tumour necrosis factor superfamily (TNFSF) are key players in immune regulation; an increase in some TNFSF molecules has been reported during severe COVID‐19. In this study, we profiled and evaluated TNFSF members in the serum of COVID‐19 vaccine‐naïve patients to identify potential biomarkers associated with disease severity.
Andy Ruiz   +14 more
wiley   +1 more source

Glycine by enteral route does not improve major clinical outcomes in severe COVID-19: a randomized clinical pilot trial

open access: yesScientific Reports
There is a worrying scarcity of drug options for patients with severe COVID-19. Glycine possesses anti-inflammatory, cytoprotective, endothelium-protective, and platelet-antiaggregant properties, so its use in these patients seems promising. In this open
Mario H. Vargas   +7 more
doaj   +1 more source

Peptidyl Arginine Deiminases in Chronic Diseases: A Focus on Rheumatoid Arthritis and Interstitial Lung Disease

open access: yesCells, 2023
Protein citrullination is accomplished by a broad enzyme family named Peptidyl Arginine Deiminases (PADs), which makes this post-translational modification in many proteins that perform physiological and pathologic mechanisms in the body.
Karol J. Nava-Quiroz   +4 more
doaj   +1 more source

The impact of circulating nucleosomes on inflammation in acute lung injury

open access: yesThe FASEB Journal, Volume 38, Issue 23, 15 December 2024.
Extracellular histones are predominantly released as nucleosomes during ALI. Extracellular nucleosomes can lead to macrophage activation and trigger inflammation in various organs. Mechanistically, nucleosomes activate the NF‐κB signaling pathway, while inhibition of NF‐κB by sulfasalazine attenuated nucleosome‐induced macrophage activation.
Saugata Dutta   +15 more
wiley   +1 more source

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