Results 71 to 80 of about 2,622 (224)

Introduction of a Double‐Headed Nucleotide Into G‐Quadruplex DNA: Position‐Dependent Stabilization and Structural Insights

open access: yesChemistry – A European Journal, EarlyView.
A double‐headed bis‐guanine (G) nucleotide (GG) was evaluated as a noncanonical building block in G‐quadruplexes (G4s). Biophysical and computational analyses reveal that GG can directly participate in G‐tetrads and strongly stabilize G4s in a position‐ and topology‐dependent manner. These findings establish design rules for using GG to engineer highly
Krista Urup   +5 more
wiley   +1 more source

Cyclization of a 1,8‐Diphenylanthracene by Scholl Reactions to Form Five‐ and Seven‐Membered Ring Embedded Polycyclic Aromatic Hydrocarbons

open access: yesChemistry – A European Journal, EarlyView.
Reactions of 10‐mesityl‐1,8‐diphenylanthracene with DDQ/TfOH produced three products via sequential formation of a five‐ or seven‐membered ring. Unexpectedly, the triply cyclized product with a rubicene substructure was formed through cyclization involving 1,2‐methyl shift.
Tatsuhiro Sasaki   +2 more
wiley   +1 more source

Combined Stability: Protecting against Combined Attacks

open access: yesTransactions on Cryptographic Hardware and Embedded Systems
Physical attacks pose serious challenges to the secure implementation of cryptographic algorithms. While side-channel analysis (SCA) has received significant attention, leading to well-established countermeasures, fault attacks and especially their ...
Dilara Toprakhisar   +2 more
doaj   +1 more source

Multivalent RNA‐Cleaving Agents on a Cubic Octameric Silsesquioxane Core

open access: yesChemistry – A European Journal, EarlyView.
RNA‐cleaving agents on a cubic octameric silsesquioxane core were synthesized and characterized. Several catalytic systems of these structures were screened using hexaribonucleotide models. The best systems were then further used to study their catalytic efficiency in cleaving a HER2 mRNA model sequence. The induced cleavage sites were also determined.
Hanni Haapsaari, Iris Tuomi, Pasi Virta
wiley   +1 more source

Access to Uncharted (Ethoxy)difluoromethylated‐Containing Tetrahydrofurans by Hydrogenation

open access: yesChemistry – A European Journal, EarlyView.
A Pd/C‐catalyzed selective hydrogenation of (ethoxy)difluoromethylated‐containing tetrahydrofurans was achieved. Depending on the pressure of H2, a divergent process led to either cis CF2CO2Et‐containing tetrahydrofurans or valuable α,α‐difluoro‐β‐hydroxyesters, offering key fluorinated building blocks for drug discovery while keeping the CF2CO2Et ...
Thibaud Charvillat   +7 more
wiley   +1 more source

TRNG Entropy Model in the Presence of Flicker FM Noise

open access: yesTransactions on Cryptographic Hardware and Embedded Systems
Flicker Frequency Modulated (FM) noise, which influences free-running Ring Oscillators (ROs), can make a substantial contribution to the entropy generated by RO-based True Random Number Generators (TRNGs).
Adriaan Peetermans, Ingrid Verbauwhede
doaj   +1 more source

Encapsulation of Linear and Cyclic Alkanes in Water Within a Dimeric Deep‐Cavity Sulfonatocalix[4]arene Capsule

open access: yesChemistry – A European Journal, EarlyView.
Captured in water. A tetrasulfonated deep‐cavity calix[4]arene encapsulates linear and cyclic alkanes, as well as benzene and hexafluorobenzene, in water by forming a self‐assembled dimeric capsule. The binding affinity is guest size‐dependent. For linear alkanes, the affinity peaks at n‐hexane, while cyclooctane is the most strongly bound cycloalkane.
Nico Schneider   +5 more
wiley   +1 more source

A Note on 5-bit Quadratic Permutations’ Classification

open access: yesIACR Transactions on Symmetric Cryptology, 2017
Classification of vectorial Boolean functions up to affine equivalence is used widely to analyze various cryptographic and implementation properties of symmetric-key algorithms.
Dušan Božilov   +2 more
doaj   +1 more source

Reversible Cystine Disulfide Scaffolding Enables Carbonyl Sulfide‐Mediated Intramolecular Peptide Bond Formation via Cyclocystine: Implications for Prebiotic Chemistry

open access: yesChemistry – A European Journal, EarlyView.
Cystine is unique among amino acids, in that the disulfide bond can allow intramolecular peptide bond formation. This cyclization offers potential advantages for intramolecular coupling selectivity in prebiotic peptide formation. ABSTRACT Treatment of cystine (the disulfide‐linked dimer of cysteine) with carbonyl sulfide (COS) results in the formation ...
Avinash Vicholous Dass   +5 more
wiley   +1 more source

Home - About - Disclaimer - Privacy