Results 111 to 120 of about 9,946,604 (349)

Medium to long-term outcome of thoracoscapular arthrodesis with screw fixation for facioscapulohumeral muscular dystrophy [PDF]

, 2013
Background: Shoulder girdle muscle weakness is the most constant feature of facioscapulohumeral muscular dystrophy and leads to scapular winging. Mechanical fixation of the scapula to the thoracic wall provides a stable fulcrum on which the deltoid ...
Atoun, Ehud, Copeland, Stephen, Levy, Ofer, Narvani, Ali, Sforza, Giuseppe, Van Tongel, Alexander   +5 more
core   +2 more sources

Mechanisms of parasite‐mediated disruption of brain vessels

FEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira, Sílvia Arroz‐Madeira, Cláudio A. Franco, Sara Silva Pereira   +3 more
wiley   +1 more source

Motivations for pursuing the Level 7 Diploma in Aesthetic Medicine: insights from a United Kingdom cohort

Journal of Cosmetic Medicine
Background : The United Kingdom aesthetic medicine sector has seen significant growth with an increasing demand for non-invasive procedures, highlighting the need for qualified professionals.
Emmaline Ashley, Anika Parmar, Priyanka Chadha, Lara Watson   +3 more
doaj   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Beauty and Health: Anthropological Perspectives [PDF]

, 2008
This essay, written as a 'teaser' for an up-coming symposium, reflects on how human beauty can be understood from an anthropological and medical anthropological perspective.
Edmonds, Alexander
core  

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

F-theorem, duality and SUSY breaking in one-adjoint Chern-Simons-Matter theories

, 2012
We extend previous work on N=2 Chern-Simons theories coupled to a single adjoint chiral superfield using localization techniques and the F-maximization principle.
Affleck, Affleck, Aganagic, Amariti, Amariti, Benini, Benvenuti, Bhattacharya, Casini, Cheon, Dolan, Gabella, Gadde, Gaiotto, Ginsparg, Giveon, Gulotta, Halmagyi, Hama, Herzog, Hwang, Imamura, Intriligator, Intriligator, Jafferis, Jafferis, Jafferis, Kapustin, Kapustin, Kapustin, Kapustin, Kinney, Klebanov, Krattenthaler, Kutasov, Kutasov, Marino, Marino, Marino, Marino, Marino, Marino, Martelli, Minwalla, Myers, Myers, Niarchos, Niarchos, Niarchos, Pasquetti, Pestun, Rains, Romelsberger, Spiridonov, Spiridonov, Spiridonov, Takeshi Morita, Vasilis Niarchos, Willett, Witten, Witten, Zamolodchikov   +61 more
core   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source