Results 111 to 120 of about 467,481 (433)

The multiple roles of the NlpC_P60 peptidase family in mycobacteria – an underexplored target for antimicrobial drug discovery

open access: yesFEBS Letters, EarlyView.
The NlpC_P60 superfamily of peptidases is recognised by its key role in bacterial cell wall homeostasis. Recently, studies have also described the involvement of NlpC_P60‐like enzymes in bacterial competitive mechanisms and pathogenesis across several lineages.
Catharina dos Santos Silva   +1 more
wiley   +1 more source

Protective Properties of Botanical Extracts against 5G Radiation-induced Damage to Human Skin, as Demonstrated in Preliminary Data from a Keratinocyte Cell Culture Model

open access: yesFrontiers in Bioscience-Landmark
Background: Next-generation 5G communication technology involves increasing use of 3–100 GHz wireless bands in population centers. Though still non-ionizing, this implies higher radiation energy vs. existing bands. The range is also shorter, needing more
Fabien Havas   +3 more
doaj   +1 more source

Sunscreen Boosting Effect by Solid Lipid Nanoparticles-Loaded Fucoxanthin Formulation

open access: yesCosmetics, 2020
Fucoxanthin is a bioactive compound that is a kind of natural carotenoid. Fucoxanthin is known to protect against UV‐B-induced cell damage in hairless mice, even though it is physiochemically unstable to heat and acid due to its polyunsaturated structure,
Yong-Jik Lee, Gae-Won Nam
doaj   +1 more source

Cable knots do not admit cosmetic surgeries [PDF]

open access: yesarXiv, 2018
Two Dehn surgeries on a knot are called purely cosmetic if their surgered manifolds are homeomorphic as oriented manifolds. Gordon conjectured that non-trivial knots in $S^3$ do not admit purely cosmetic surgeries. In this article, we confirm this conjecture for cable knots.
arxiv  

Biologically active properties of plant extracts in cosmetic emulsions [PDF]

open access: yes, 2020
Describes biologically active properties waters plant extracts of domestic herbaceous species as a part cosmetic emulsion in this article. In particular, the antioxidant features related to vitamins, flavonoids, coloring, extractive and tannins were ...
Harhaun, Ruslana   +3 more
core   +1 more source

Making tau amyloid models in vitro: a crucial and underestimated challenge

open access: yesFEBS Letters, EarlyView.
This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley   +1 more source

The Cosmetic Circumcision

open access: yesThe Journal of Sexual Medicine, 2013
A penile injection of 10–20 mcg prostaglandin E1 is given with a 31-gauge 8-mm needle at the beginning of the case to provide the patient with an erection. This helps the surgeon determine how much skin needs to be removed. While the penis remains erect, the foreskin is pulled over the glans penis, and released. The skin at the base of the penile shaft
openaire   +3 more sources

Unraveling Mycobacterium tuberculosis acid resistance and pH homeostasis mechanisms

open access: yesFEBS Letters, EarlyView.
Mycobacterium tuberculosis exhibits a remarkable resilience to acid stress. In this Review, we discuss some of the molecular mechanisms and metabolic pathways used by the tubercle bacilli to adapt and resist host‐mediated acid stress. Mycobacterium tuberculosis (Mtb) is a successful pathogen that has developed a variety of strategies to survive and ...
Janïs Laudouze   +3 more
wiley   +1 more source

The popularization of orodispersible tablets in the pharmaceutical market [PDF]

open access: yesInfarma: Pharmaceutical Sciences, 2018
Orodispersible tablets are getting popular due to its easy administration which leads to a higher therapeutic adherence. This study aimed to evaluate the state of the art of these drug products based on the scientific literature.
Ludmila Alvim PINHO   +4 more
doaj   +1 more source

Refining the NaV1.7 pharmacophore of a class of venom‐derived peptide inhibitors via a combination of in silico screening and rational engineering

open access: yesFEBS Letters, EarlyView.
Venom peptides have shown promise in treating pain. Our study uses computer screening to identify a peptide that targets a sodium channel (NaV1.7) linked to chronic pain. We produced the peptide in the laboratory and refined its design, advancing the search for innovative pain therapies.
Gagan Sharma   +8 more
wiley   +1 more source

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