Results 141 to 150 of about 34,734 (271)

Small Nucleotide Variant Analysis Using RNA Fusion Panel (SMURF): Making the Most of RNAseq Data in Solid Tumours

open access: yesJournal of Clinical Laboratory Analysis, EarlyView.
RNA‐based fusion panels using targeted next‐generation sequencing of formalin‐fixed paraffin‐embedded (FFPE) tumour tissue specimens have been used for a few years from patients with various tumour types to detect rearrangements/fusions. Using the bioinformatic approaches the data obtained from RNA sequencing (RNAseq) can also be used for small ...
Pranav Dorwal   +14 more
wiley   +1 more source

The Physical Origin of Extreme Emission Line Galaxies at High Redshifts: Strong [O iii] Emission Lines Produced by Obscured Active Galactic Nuclei

open access: yesThe Astrophysical Journal
We present deep Subaru/FOCAS spectra for two extreme emission line galaxies (EELGs) at z ∼ 1 with strong [ O iii ] λ 5007 emission lines, exhibiting equivalent widths (EWs) of $290{5}_{-578}^{+946}$ Å and $200{0}_{-159}^{+188}$ Å, comparable to those of ...
Chenghao Zhu   +23 more
doaj   +1 more source

Geochronology of the Whittlesey sedimentary succession, eastern England: The ‘Pompeii’ of the British late Middle Pleistocene to Holocene record

open access: yesJournal of Quaternary Science, EarlyView.
Abstract The sedimentary succession at Whittlesey preserves a unique British late Middle Pleistocene to Holocene record back to a time equivalent to at least marine oxygen isotope stage 8 (ca. 250 ka). This study builds on previously published sedimentology, geochronology and palaeoecology results to establish 20 sedimentary facies associations, with ...
H. E. Langford   +3 more
wiley   +1 more source

Assessing the intensity of Late Quaternary humid phases in the Nefud Desert, northern Arabia

open access: yesJournal of Quaternary Science, EarlyView.
ABSTRACT The climate history of the major dryland zones of the world, such as the Saharo–Arabian Desert belt, plays a key role in the dispersal of early humans through these intermittently inhospitable regions. Here, we assess the relative intensity of Late Quaternary humid phases in northern Arabia through lithological, geochemical, palaeoecological ...
Richard Clark‐Wilson   +9 more
wiley   +1 more source

Variations of cosmic rays and problems of solar-terrestrial physics [PDF]

open access: yes
Solar cosmic ray variations and their relationship to solar physics, solar wind magnetic fields, electromagnetic radiation, and radiation hazards to manned space ...
Dorman, L. I.
core   +1 more source

Modular and Automated Workflow for Streamlined Raman Signal Analysis

open access: yesJournal of Raman Spectroscopy, EarlyView.
This study presents an automated workflow for preprocessing and analyzing Raman spectroscopy data, addressing key challenges such as noise suppression, baseline correction, and peak fitting using Voigt profiles. The method is validated on both synthetic and experimental spectra, demonstrating improved spectral fidelity and peak detection for biomedical
Mykyta Kizilov   +3 more
wiley   +1 more source

PeV Neutrinos Observed by IceCube from Cores of Active Galactic Nuclei [PDF]

open access: yes
I show that the high energy neutrino flux predicted to arise from active galactic nuclei cores can explain the PeV neutrinos detected by IceCube without conflicting with the constraints from the observed extragalactic cosmic-ray and gamma-ray ...
Stecker, Floyd W.
core   +1 more source

Exome Sequencing Identifies Variants in MLH1 and ERBB2 as Potential Cancer‐Predisposing Factors in Familial Early‐Onset Colorectal Cancer

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Colorectal cancer (CRC) has raised considerable health concerns worldwide, with increasing incidence rates, specifically among younger populations. Despite remarkable progress in diagnosing and treating various diseases, the genetic basis of CRC remains only partially understood.
Behnaz Bagheri   +7 more
wiley   +1 more source

Mid‐Infrared Integrated Photonics: Material Platforms and Emerging Applications

open access: yesLaser &Photonics Reviews, EarlyView.
Mid‐infrared (MIR) integrated photonics enables advanced chemical and biological sensing through the unique absorption features of molecules in the 2–20 µm range. This review highlights recent material advances such as chalcogenide glasses, silicon, and graphene and explores MIR applications in environmental monitoring, medical diagnostics ...
Muhammad Ali Butt   +2 more
wiley   +1 more source

Levodopa‐Carbidopa Intestinal Gel Improves Dyskinesia in Parkinson's Disease: Post Hoc Analysis from the COSMOS Study

open access: yesMovement Disorders Clinical Practice, EarlyView.
Abstract Background Dyskinesia is a debilitating complication of dopaminergic therapy in advanced Parkinson's disease. Objectives To evaluate the effect of levodopa‐carbidopa intestinal gel (LCIG) on dyskinesia burden. Methods This is a post hoc analysis of the retrospective, observational COmedication Study assessing Mono‐ and cOmbination therapy with
Alfonso Fasano   +11 more
wiley   +1 more source

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