Results 111 to 120 of about 347,393 (310)

Arid1a Deficiency Drives Aristolochic Acid‐Induced Liver Tumorigenesis through Ctnnb1 Mutation and Defective Nucleotide Excision Repair

open access: yesAdvanced Science, EarlyView.
ARID1A is frequently mutated in both non‐malignant tissues and cancers, but its role in tumor development after exposure to genotoxic carcinogen remains unclear. It is found that aristolochic acid I accelerated liver tumorigenesis in ARID1A‐deficient context by impairing nucleotide excision repair and enhancing carcinogen bioactivation, revealing key ...
Lan Wang   +8 more
wiley   +1 more source

Metaphor as a cognitive and relational tool for self-narrating experience of addiction: a qualitative-quantitative analysis

open access: yesFrontiers in Psychology
IntroductionMetaphors have been acknowledged as crucial for understanding and articulating complex experiences, helping individuals make sense of emotional and social challenges, especially during tough times.
Daniela Altavilla   +9 more
doaj   +1 more source

Catalyst‐Free Collagen Filament Crosslinking for Engineering Anisotropic and Mechanically Robust Tissue Scaffolds

open access: yesAdvanced Science, EarlyView.
A bioorthogonal rhodamine/PEG crosslinking strategy is introduced to engineer dense collagen hydrogels with high mechanical resilience and cytocompatibility. Integration with wet‐spinning enables the fabrication of uniaxially aligned, cell‐laden collagen filaments that activate mechanotransductive signaling and support functional muscle regeneration in
JuYeon Kim   +4 more
wiley   +1 more source

AI‐Guided SERS Defines a Pan‐Cancer Diagnostic Biomarker

open access: yesAdvanced Science, EarlyView.
An AI‐enabled SERS platform integrates automated exosome enrichment with molecular fingerprinting to enable accurate early detection and differential diagnosis of ten common cancers. The system identifies exosomal dATP as a universal Raman biomarker, offering a scalable, noninvasive, and clinically translatable approach for precision oncology ...
Cai Zhang   +15 more
wiley   +1 more source

The EEE Project: cosmic rays, multigap resistive plate chambers and high school students [PDF]

open access: bronze, 2012
M. Abbrescia   +54 more
openalex   +1 more source

Integrating Automated Electrochemistry and High‐Throughput Characterization with Machine Learning to Explore Si─Ge─Sn Thin‐Film Lithium Battery Anodes

open access: yesAdvanced Energy Materials, Volume 15, Issue 11, March 18, 2025.
A closed‐loop, data‐driven approach facilitates the exploration of high‐performance Si─Ge─Sn alloys as promising fast‐charging battery anodes. Autonomous electrochemical experimentation using a scanning droplet cell is combined with real‐time optimization to efficiently navigate composition space.
Alexey Sanin   +7 more
wiley   +1 more source

Product differentiation in the fruit industry: Lessons from trademarked apples

open access: yesAgribusiness, EarlyView.
Abstract We derive price premiums for patented or trademarked apple varieties, also known as “club apples,” compared to open‐variety apples. We use an expansive retail scanner dataset, along with unique data on apple taste characteristics, to estimate monthly club apple premiums for 2008–2018.
Modhurima Dey Amin   +3 more
wiley   +1 more source

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