Results 171 to 180 of about 353,889 (361)

Chinese pan‐cancer patient genomic characteristics: A comprehensive analysis based on the National Cancer Center–Clinical Diagnostics Knowledgebase real‐world clinical sequencing cohort

Interdisciplinary Medicine, EarlyView.
We assembled National Cancer Center–Clinical Diagnostics Knowledgebase, a clinical genomic knowledgebase of 6935 tumors with matched normal samples, revealing key somatic alterations and actionable variants (70.2% of the cohort). Enrichment of certain different gene mutations was observed between Chinese and American populations, along with a strong ...
Hongrui Li, Shun Wang, Guowei Zhao, Jiangtao Li, Xin Li, Bingning Wang, Yi Zhang, Mengfei Yao, Lei Guo, Jianming Ying, Wenbin Li   +10 more
wiley   +1 more source

Towards Water, Food and Energy Security: The Global Challenges and Possible Solutions for a Holistic Vision of Sustainability

Irrigation and Drainage, EarlyView.
ABSTRACT This invited paper gives an overview of the challenges the world is facing and offers a possible solution for water and food security within the holistic integrated concept of the water–energy–food (WEF) nexus. The paper summarizes the experience the author gained through working on various research projects at national and international ...
Ragab Ragab
wiley   +1 more source

Small Nucleotide Variant Analysis Using RNA Fusion Panel (SMURF): Making the Most of RNAseq Data in Solid Tumours

Journal of Clinical Laboratory Analysis, EarlyView.
RNA‐based fusion panels using targeted next‐generation sequencing of formalin‐fixed paraffin‐embedded (FFPE) tumour tissue specimens have been used for a few years from patients with various tumour types to detect rearrangements/fusions. Using the bioinformatic approaches the data obtained from RNA sequencing (RNAseq) can also be used for small ...
Pranav Dorwal, Julie Robin, Broden Krause, Patricia Pyrchla, Bin Yuan, Robert Quach, Anna Fong Na Goh, Pamela Htain, Noel Djitro, Amit Kumar, Liyan Song, Priscillia Siswara, Suzanne Svobodova, Peter Kaub, Beena Kumar   +14 more
wiley   +1 more source

Revisiting metastable cosmic string breaking

Journal of High Energy Physics
Metastable cosmic strings appear in models of new physics with a two-step symmetry breaking G → H → 1, where π 1(H) ≠ 0 and π 1(G) = 0. They decay via the monopole-antimonopole pair creation inside. Conventionally, the breaking rate has been estimated by
Akifumi Chitose, Masahiro Ibe, Yuhei Nakayama, Satoshi Shirai, Keiichi Watanabe   +4 more
doaj   +1 more source

Geochronology of the Whittlesey sedimentary succession, eastern England: The ‘Pompeii’ of the British late Middle Pleistocene to Holocene record

Journal of Quaternary Science, EarlyView.
Abstract The sedimentary succession at Whittlesey preserves a unique British late Middle Pleistocene to Holocene record back to a time equivalent to at least marine oxygen isotope stage 8 (ca. 250 ka). This study builds on previously published sedimentology, geochronology and palaeoecology results to establish 20 sedimentary facies associations, with ...
H. E. Langford, M. D. Bateman, R. M. Briant, D. J. Horne   +3 more
wiley   +1 more source

Fin whale song recordings by onshore seismometers open new horizons for cetacean coastal monitoring

Scientific Reports
Fin whales, the second largest animal on Earth, produce one of the most intense vocalisations in the animal kingdom. Monitoring these songs using ocean-deployed hydrophones plays an important role in the study of fin whale distribution and social ...
Martin Möllhoff, Christopher J. Bean
doaj   +1 more source

Assessing the intensity of Late Quaternary humid phases in the Nefud Desert, northern Arabia

Journal of Quaternary Science, EarlyView.
ABSTRACT The climate history of the major dryland zones of the world, such as the Saharo–Arabian Desert belt, plays a key role in the dispersal of early humans through these intermittently inhospitable regions. Here, we assess the relative intensity of Late Quaternary humid phases in northern Arabia through lithological, geochemical, palaeoecological ...
Richard Clark‐Wilson, Simon J. Armitage, Ian Candy, Paul S. Breeze, Nick A. Drake, Huw S. Groucutt, Abdullah M. Alsharekh, Faisal Al‐Jibreen, Michael D. Petraglia, David B. Ryves   +9 more
wiley   +1 more source

Modular and Automated Workflow for Streamlined Raman Signal Analysis

Journal of Raman Spectroscopy, EarlyView.
This study presents an automated workflow for preprocessing and analyzing Raman spectroscopy data, addressing key challenges such as noise suppression, baseline correction, and peak fitting using Voigt profiles. The method is validated on both synthetic and experimental spectra, demonstrating improved spectral fidelity and peak detection for biomedical
Mykyta Kizilov, Vsevolod Cheburkanov, Joseph Harrington, Vladislav V. Yakovlev   +3 more
wiley   +1 more source

On the Source Contribution to the Galactic Diffuse Gamma Rays above 398 TeV Detected by the Tibet ASγ Experiment

The Astrophysical Journal Letters
Potential contribution from gamma-ray sources to the Galactic diffuse gamma rays observed above 100 TeV (sub-PeV energy range) by the Tibet AS γ experiment is an important key to interpreting recent multimessenger observations.
S. Kato, D. Chen, J. Huang, T. Kawashima, K. Kawata, A. Mizuno, M. Ohnishi, T. Sako, T. K. Sako, M. Takita, Y. Yokoe   +10 more
doaj   +1 more source

The NOEMA observations of GN-z11: constraining the neutral interstellar medium and dust formation in the heart of cosmic reionization at z = 10.6 [PDF]

Yoshinobu Fudamoto, Pascal A. Oesch, Fabian Walter, Roberto Decarli, C. L. Carilli, Andrea Ferrara, Laia Barrufet, R. J. Bouwens, M. Dessauges‐Zavadsky, Erica J. Nelson, H. Dannerbauer, G. D. Illingworth, Akio Inoue, R. Marques-Chaves, I. Pérez‐Fournon, Dominik A. Riechers, D. Schaerer, Renske Smit, Yuma Sugahara, P. van der Werf   +19 more
openalex   +1 more source