Results 191 to 200 of about 91,143 (269)

SigRescueR: a pan-system framework for noise correction and mutational signature identification across sequencing platforms. [PDF]

Brief Bioinform
Nguyen PT, Zhivagui M.
europepmc   +1 more source

A bifacial paradise—The site of Ochtmissen, Germany, and its lithic assemblage in the context of the last glacial (early MIS 4) in the north‐central European Lowland

Boreas, EarlyView.
The Palaeolithic site of Ochtmissen (Lower Saxony, Germany) was excavated in fluvial terrace deposits during the winter of 1993/1994. The current study presents, for the first time, a thorough analysis of the lithic assemblage, encompassing its primary technological and typological characteristics, as well as the type and age of the fluvial deposits ...
Gianpiero Di Maida, Jutta Winsemann, Markus Fuchs, Niklas von Soest, Thomas Terberger   +4 more
wiley   +1 more source

Database of recurrent mutations, an unbiased web resource to browse recurrent mutations in cancers. [PDF]

iScience
Chakroborty D, Vaparanta K, Ghimire B, Paatero I, Kurppa KJ, Elenius K.   +5 more
europepmc   +1 more source

Single‐grain K‐feldspar luminescence dating on primary and re‐deposited aeolian sediments in Mongolia

Boreas, EarlyView.
Owing to its location in the semi‐arid region of northern Central Asia, Mongolia is highly sensitive to climate change and therefore provides an excellent setting for palaeoenvironmental research. Proxy data from different sediment types are crucial for interpreting past climate changes and landscape evolution, while burial ages provide chronological ...
Junjie Zhang, Michael Klinge, Sumiko Tsukamoto, Daniela Sauer, Manfred Frechen   +4 more
wiley   +1 more source

Radiation-Resistant Microbes: Pioneers for Life Beyond Earth. [PDF]

Curr Microbiol
Coleine C, Cordero RJ.
europepmc   +1 more source

AlpIce‐1: a database of geochronological and geomorphological constraints on Alps‐wide palaeoglacier fluctuations between the Last Glacial Maximum and the Holocene

Boreas, EarlyView.
The AlpIce‐1 database is the first compilation of published geomorphological and geochronological markers constraining build‐up, culmination and decay of glaciers from the Last Glacial Maximum through the Holocene across the entire European Alps. AlpIce‐1 integrates more than 4200 surface‐exposure and radiocarbon ages, homogenized, quality controlled ...
Sarah Kamleitner, Susan Ivy‐Ochs, Tancrède P. M. Leger, Andreas Henz, Samuel U. Nussbaumer, Andreas Vieli, Guillaume Jouvet   +6 more
wiley   +1 more source

Synonymous and non-synonymous variants at splice junctions can disrupt splicing and are frequently linked to disease associated loss of function genes. [PDF]

BMC Genomics
Srinivasan S, Subramanian S, Zhou H, Hoppmann A, Metzger P, Boerries M, Ramamoorthy S.   +6 more
europepmc   +1 more source

Genetic Evolution in BRCA1‐Associated Breast Cancer Reveals Early Driver Mutations Shaping Tumor Features and Prognosis

Cancer Science, EarlyView.
Multi‐region sequencing of 57 BRCA1‐associated breast cancers identified TP53 as the dominant initial driver, defining a triple‐negative subgroup with biallelic BRCA1 loss and elevated genomic instability. TP53 truncating mutations were enriched in BRCA1 carriers and linked to reduced HRD, EMT activation, and a trend toward worse survival.
Li Hu, Zhongwu Li, Qiting Wan, Xingyu Liao, Yaxin Zhang, Qian Liu, Xinyun Ding, Hua Meng, Yifan Wu, Jie Sun, Juan Zhang, Lu Yao, Ye Xu, Yuntao Xie   +13 more
wiley   +1 more source

Generative modeling reveals the connection between cellular morphology and gene expression

Wen S, Viñas Torné R, Bues J, Lambert CL, Grenningloh N, Ferrari T, Bugani E, Pezoldt J, Love JR, Karthaus W, Deplancke B, Brbić M.   +11 more
europepmc   +1 more source