Results 191 to 200 of about 88,706 (269)

Mutational Signature‐Based Biomarker for Phase II Trial of Olaparib Maintenance in Advanced High‐Grade Ovarian Cancer

Cancer Science, EarlyView.
A whole‐exome sequencing–based mutational signature biomarker (MSBM) identified an HRD‐enriched population in advanced ovarian cancer. In a phase II trial, olaparib maintenance suggested clinically meaningful PFS benefit without bevacizumab, supporting MSBM as a complementary HRD assessment approach.
Katsutoshi Oda, Daisuke Shintani, Akira Nishijima, Mayuyo Mori, Kazuyoshi Kato, Shoji Nagao, Noriomi Matsumura, Masahiro Kagabu, Masataka Takenaka, Kosuke Yoshihara, Yosuke Konno, Junzo Hamanishi, Sho Sato, Shiro Takamatsu, Keiko Ueda, Kosuke Kashiwabara, Takashi Aoki, Kunihiro Nishimura, Kenji Tatsuno, Hiroyuki Aburatani, Kosei Hasegawa   +20 more
wiley   +1 more source

An exploration of the structure and understanding of <i>Xin</i> ("") in Chinese culture: the development of a theoretical model and questionnaire instruments. [PDF]

Front Psychol
Lin L, Jing D, Sun C.
europepmc   +1 more source

Scalable Computation of Topological Abstractions for Scalar Data

Computer Graphics Forum, EarlyView.
Abstract Topological data analysis has become an important tool for large scale scalar data analysis and visualization, efficiently extracting the inherent structure and features of interest of the data. However, with growing dataset sizes and complexity, it is increasingly becoming infeasible to compute topological abstractions of interest in serial ...
M. Will, J. Lukasczyk, J. Tierny, A. Gyulassy, G. H. Weber, H. Carr, C. Garth   +6 more
wiley   +1 more source

Increased and varied radiation during the Sun's encounters with cold clouds in the last 10 million years. [PDF]

Sci Rep
Opher M, Giacalone J, Loeb A, Economo EP, Cummings A, Middleton J, Zucker C, Miller JA, Nica A, Hatzaki M.   +9 more
europepmc   +1 more source

Cristiano of Arabia: Did Ronaldo increase Saudi Pro League attendances?

Contemporary Economic Policy, Volume 43, Issue 2, Page 260-270, April 2025.
Abstract In December 2022, Cristiano Ronaldo, five‐time Ballon d’Or winner and the most‐followed person on Instagram, signed for Al‐Nassr in the Kingdom of Saudi Arabia. This marked one of several expensive, recent interventions by the kingdom in global sports markets. We exploit the timing of this event to estimate superstar effects.
Dominik Schreyer, Carl Singleton
wiley   +1 more source

Exploring the Potential Observations Between Geomagnetic Activity and Cardiovascular Events: A Scoping Review. [PDF]

Cureus
Belenko J, Cancel G, Mayrovitz HN.
europepmc   +1 more source

Cosmic superstrings

Physics Letters B, 1985
openaire   +1 more source

Production of secondary particles from cosmic ray interactions in the earth's atmosphere: Implications for annual effective dose, 14C/12C ratio, and magnetic field effects. [PDF]

PLoS One
Hassanpour M, Rezaie M, Heydarizade Y, Rashed Iqbal Faruque M, Hassanpour M.   +4 more
europepmc   +1 more source

Curating the Unexpected: Stéphane Thidet's “Weeping Stones” Transformed During COVID‐19

Curator: The Museum Journal, EarlyView.
ABSTRACT A monumental work by French artist Stéphane Thidet became the nexus for an unexpected interaction between an art installation and wildlife. “Weeping Stones,” which presents a desert‐like world, devoid of greenery, was featured in an exhibition we co‐curated at the Genia Schreiber University Gallery, Tel Aviv, Israel, in January 2020.
Tamar Mayer, Sefy Hendler, Asaf Ben‐David, Darya Aloufy   +3 more
wiley   +1 more source

BASCULE: bayesian inference and clustering of mutational signatures leveraging biological priors. [PDF]

Genome Biol
Buscaroli E, Sadr A, Bergamin R, Milite S, Villegas Garcia EN, Tasciotti A, Ansuini A, Ramazzotti D, Calonaci N, Caravagna G.   +9 more
europepmc   +1 more source