Results 201 to 210 of about 91,143 (269)

An exploration of the structure and understanding of <i>Xin</i> ("") in Chinese culture: the development of a theoretical model and questionnaire instruments. [PDF]

Front Psychol
Lin L, Jing D, Sun C.
europepmc   +1 more source

Evidence That the Protein Phosphatase Activity of PTEN Contributes to Embryonic Development and Tumor Suppression

Cancer Science, EarlyView.
Mice expressing only mutant PTEN Y138L, a protein which shows normal suppression of cellular AKT yet lacks protein phosphatase activity, die in utero, and heterozygous mice display a range of tumors. This indicates both the lipid and protein phosphatase activities of PTEN work together for normal tumor suppression and embryonic development.
Priyanka Tibarewal, Laura Spinelli, Nisha Kriplani, Helen Wise, Nadege Poncet, Giulia Marzano, Karen E. Anderson, Katarzyna M. Grzes, Zofia Varyova, Mahreen Adil, C. Peter Downes, Phillip T. Hawkins, Len R. Stephens, Kate G. Storey, Doreen A. Cantrell, Bart Vanhaesebroeck, Nicholas R. Leslie   +16 more
wiley   +1 more source

Global Geo-Pharmacogenomics: Environmental Mutational Signatures Drive Population-Level Heterogeneity in Anticancer Drug Response. [PDF]

J Xenobiot
Jawahar J, James S.
europepmc   +1 more source

Elucidating PI3K/AKT/PTEN Pathway Alterations at Single‐Cell Level in CTCs From HR+/HER2− Metastatic Breast Cancer

Cancer Science, EarlyView.
Single CTC analysis revealed extensive inter‐ and intra‐patient heterogeneity of PI3K/AKT/PTEN pathway alterations in HR+/HER2− metastatic breast cancer, capturing both SNVs and CNAs, including PTEN loss‐of‐function events. Longitudinal CTC profiling also uncovered dynamic clonal evolution, highlighting its potential to complement tissue and ctDNA ...
Tania Rossi, Michela Palleschi, Caterina Gianni, Filippo Merloni, Alessandra Virga, Sara Bandini, Davide Angeli, Michela Tebaldi, Roberta Maltoni, Paola Ulivi, Antonino Musolino   +10 more
wiley   +1 more source

AstroOphthalmology: Basic and Pathophysiological Concepts of Space-Induced Ocular Changes. [PDF]

Eye Brain
Cheraqpour K, Shahriari M, Ghazi M, Heydari N, Moshfeghi S, Mousavi Ganji SM, Asgari S, Cheraqpour S.   +7 more
europepmc   +1 more source

Scalable Computation of Topological Abstractions for Scalar Data

Computer Graphics Forum, EarlyView.
Abstract Topological data analysis has become an important tool for large scale scalar data analysis and visualization, efficiently extracting the inherent structure and features of interest of the data. However, with growing dataset sizes and complexity, it is increasingly becoming infeasible to compute topological abstractions of interest in serial ...
M. Will, J. Lukasczyk, J. Tierny, A. Gyulassy, G. H. Weber, H. Carr, C. Garth   +6 more
wiley   +1 more source

Exploring the Potential Observations Between Geomagnetic Activity and Cardiovascular Events: A Scoping Review. [PDF]

Cureus
Belenko J, Cancel G, Mayrovitz HN.
europepmc   +1 more source

The PRIME trial: An investigator‐initiated, multicentre, phase II study of the poly(ADP‐ribose) polymerase inhibitor olaparib in isocitrate dehydrogenase (IDH)‐mutated relapsed/refractory acute myeloid leukaemia and myelodysplastic syndromes

British Journal of Haematology, EarlyView.
Rory M. Shallis, Jennifer VanOudenhove, Namrata Chandhok, Justin Watts, Deepa Jeyakumar, Daniel R. Reed, Jan Phillip Bewersdorf, Diane Durecki, Scott Boerner, Richard F. Little, Steven D. Gore, Jing Li, Xun Bao, Li Chen, Sayak Ghatak, Thomas Prebet, Ranjit S. Bindra, Amer M. Zeidan, Stephanie Halene   +18 more
wiley   +1 more source

Survey on Compositional 3D Indoor Scene Generation

Computer Graphics Forum, EarlyView.
This survey provides a comprehensive overview of compositional 3D indoor scene generation, introducing a unified framework for categorizing existing methods, comparing their strengths and limitations and identifying key challenges and future research directions.
H. I. I. Tam, H. I. D. Pun, A. T. Wang, X. Sun, Q. Wu, H. Lee, A. X. Chang, M. Savva   +7 more
wiley   +1 more source

Production of secondary particles from cosmic ray interactions in the earth's atmosphere: Implications for annual effective dose, 14C/12C ratio, and magnetic field effects. [PDF]

PLoS One
Hassanpour M, Rezaie M, Heydarizade Y, Rashed Iqbal Faruque M, Hassanpour M.   +4 more
europepmc   +1 more source