Results 181 to 190 of about 88,706 (269)

Database of recurrent mutations, an unbiased web resource to browse recurrent mutations in cancers. [PDF]

iScience
Chakroborty D, Vaparanta K, Ghimire B, Paatero I, Kurppa KJ, Elenius K.   +5 more
europepmc   +1 more source

Refining the timing of Middle Pleistocene (MIS 12 to MIS 6) ice advances into northern central Europe: sedimentological analysis and single‐grain luminescence dating of glaciotectonic complexes and tunnel‐valley fills

Boreas, EarlyView.
We summarize the current state of knowledge on the age of the Middle Pleistocene ice advances into northern central Europe and provide 25 new single‐grain feldspar luminescence ages of Elsterian and Saalian glacigenic sediments to constrain the age of the ice advances and their tentative correlation with marine isotope stages/substages.
Niklas von Soest, Neda Rahimzadeh, Debra Colarossi, Falko Malis, Tobias Lauer, Wera Sander‐Beuermann, Yvonne Spychala, Christian Brandes, Runa Fälber, Sumiko Tsukamoto, Jutta Winsemann   +10 more
wiley   +1 more source

SigRescueR: a pan-system framework for noise correction and mutational signature identification across sequencing platforms. [PDF]

Brief Bioinform
Nguyen PT, Zhivagui M.
europepmc   +1 more source

Luminescence dating of coastal deposits from the Chanthaburi Plain, Thailand

Boreas, EarlyView.
The ongoing global sea‐level rise urges us to better understand the dynamics of coastal processes for predicting future changes. Sedimentary deposits reflect past coastal environments but require precise chronological data to place evidence into a temporal context.
Margarita Nuss, Sakonvan Chawchai, Savanna Kager, Smith Leknettip, Yunyi Li, Kannika Wangritthikraikul, Frank Preusser   +6 more
wiley   +1 more source

Global Geo-Pharmacogenomics: Environmental Mutational Signatures Drive Population-Level Heterogeneity in Anticancer Drug Response. [PDF]

J Xenobiot
Jawahar J, James S.
europepmc   +1 more source

Entrepreneurial State as a Creative Destroyer: Comparison of Hong Kong and Singapore's Creative Industries

Creativity and Innovation Management, EarlyView.
ABSTRACT This paper explores the limits of mission‐directed entrepreneurial states by drawing on the theory of recombinant innovation and F.A. Hayek's insights on the spontaneous growth of knowledge in society. First, the use of discretionary policymaking curtails the range of knowledge generated in the process of social interaction, limiting the scope
Bryan Cheang, Praharsh Mehrotra
wiley   +1 more source

Synonymous and non-synonymous variants at splice junctions can disrupt splicing and are frequently linked to disease associated loss of function genes. [PDF]

BMC Genomics
Srinivasan S, Subramanian S, Zhou H, Hoppmann A, Metzger P, Boerries M, Ramamoorthy S.   +6 more
europepmc   +1 more source

Cosmic Rays [PDF]

Nature, 1950
openaire   +2 more sources

TONSL Promotes Hepatocellular Carcinoma Progression by Inhibiting Apoptosis Through Homologous Recombination Repair

Cancer Science, EarlyView.
In hepatocellular carcinoma, the 8q24.3 locus is frequently amplified and is associated with tumor‐specific overexpression of TONSL. TONSL promotes homologous recombination repair through RAD51, limits γH2AX accumulation and apoptosis, supports tumor growth, and its loss increases sensitivity to poly (ADP‐ribose) polymerase (PARP) inhibition.
Akinori Tsujimoto, Hajime Otsu, Takashi Ofuchi, Tomohiko Ikehara, Kosuke Hirose, Shohei Shibuta, Kazuki Omachi, Yu Takahashi, Yuya Ono, Satoshi Higuchi, Takanari Tatsumi, Kiyotaka Hosoda, Qingjiang Hu, Yusuke Yonemura, Takaaki Masuda, Masayuki Sho, Koshi Mimori   +16 more
wiley   +1 more source

AstroOphthalmology: Basic and Pathophysiological Concepts of Space-Induced Ocular Changes. [PDF]

Eye Brain
Cheraqpour K, Shahriari M, Ghazi M, Heydari N, Moshfeghi S, Mousavi Ganji SM, Asgari S, Cheraqpour S.   +7 more
europepmc   +1 more source