Results 201 to 210 of about 856,925 (387)

Gene signatures characterizing driver mutations in lung squamous carcinoma are predictive of the progression of pre‐cancer lesions

International Journal of Cancer, EarlyView.
What's New? Lung squamous cell carcinoma (LUSC) is more aggressive than lung adenocarcinoma, and is most often diagnosed at an advanced stage. Here, the authors evaluated gene expression data from LUSC tumors and came up with gene signatures for 34 genetic abnormalities whose expression changes throughout different precancerous stages. Several of these
Yupei Lin, Venugopalareddy Mekala, Jianrong Li, Xiang Wang, Muhammad Aminu, Jia Wu, Jianjun Zhang, Robert Taylor Ripley, Christopher I. Amos, Chao Cheng   +9 more
wiley   +1 more source

Detecting TP53 mutations in paired liquid and tissue biopsies from patients with high‐grade serous ovarian carcinoma

International Journal of Cancer, EarlyView.
What's New? High‐grade serous ovarian carcinoma is often diagnosed at advanced stages due to non‐specific symptoms and the lack of reliable screening methods. This proof‐of‐concept study introduces a novel TP53 mutation panel using unique molecular identifier‐based next‐generation sequencing for sensitive detection of high‐grade serous ovarian ...
Amanda Olsson Widjaja, Peter Micallef, Maria Lycke, Tobias Österlund, Manuel Luna Santamaría, Julia Hedlund Lindberg, Therese Carlsson, Ulf Gyllensten, Anders Ståhlberg, Benjamin Ulfenborg, Anna Linder, Karin Sundfeldt   +11 more
wiley   +1 more source

Revisiting metastable cosmic string breaking

Journal of High Energy Physics
Metastable cosmic strings appear in models of new physics with a two-step symmetry breaking G → H → 1, where π 1(H) ≠ 0 and π 1(G) = 0. They decay via the monopole-antimonopole pair creation inside. Conventionally, the breaking rate has been estimated by
Akifumi Chitose, Masahiro Ibe, Yuhei Nakayama, Satoshi Shirai, Keiichi Watanabe   +4 more
doaj   +1 more source

Analyzing Functional Changes in BPMN Models using COSMIC

, 2017
Wiem Khlif, Mariem Haoues, Asma Sellami, Hanêne Ben‐Abdallah   +3 more
openalex   +1 more source

Chinese pan‐cancer patient genomic characteristics: A comprehensive analysis based on the National Cancer Center–Clinical Diagnostics Knowledgebase real‐world clinical sequencing cohort

Interdisciplinary Medicine, EarlyView.
We assembled National Cancer Center–Clinical Diagnostics Knowledgebase, a clinical genomic knowledgebase of 6935 tumors with matched normal samples, revealing key somatic alterations and actionable variants (70.2% of the cohort). Enrichment of certain different gene mutations was observed between Chinese and American populations, along with a strong ...
Hongrui Li, Shun Wang, Guowei Zhao, Jiangtao Li, Xin Li, Bingning Wang, Yi Zhang, Mengfei Yao, Lei Guo, Jianming Ying, Wenbin Li   +10 more
wiley   +1 more source

Fin whale song recordings by onshore seismometers open new horizons for cetacean coastal monitoring

Scientific Reports
Fin whales, the second largest animal on Earth, produce one of the most intense vocalisations in the animal kingdom. Monitoring these songs using ocean-deployed hydrophones plays an important role in the study of fin whale distribution and social ...
Martin Möllhoff, Christopher J. Bean
doaj   +1 more source

Towards Water, Food and Energy Security: The Global Challenges and Possible Solutions for a Holistic Vision of Sustainability

Irrigation and Drainage, EarlyView.
ABSTRACT This invited paper gives an overview of the challenges the world is facing and offers a possible solution for water and food security within the holistic integrated concept of the water–energy–food (WEF) nexus. The paper summarizes the experience the author gained through working on various research projects at national and international ...
Ragab Ragab
wiley   +1 more source

Small Nucleotide Variant Analysis Using RNA Fusion Panel (SMURF): Making the Most of RNAseq Data in Solid Tumours

Journal of Clinical Laboratory Analysis, EarlyView.
RNA‐based fusion panels using targeted next‐generation sequencing of formalin‐fixed paraffin‐embedded (FFPE) tumour tissue specimens have been used for a few years from patients with various tumour types to detect rearrangements/fusions. Using the bioinformatic approaches the data obtained from RNA sequencing (RNAseq) can also be used for small ...
Pranav Dorwal, Julie Robin, Broden Krause, Patricia Pyrchla, Bin Yuan, Robert Quach, Anna Fong Na Goh, Pamela Htain, Noel Djitro, Amit Kumar, Liyan Song, Priscillia Siswara, Suzanne Svobodova, Peter Kaub, Beena Kumar   +14 more
wiley   +1 more source

Anomalies in the topology of the temperature fluctuations in the cosmic microwave background: An analysis of the NPIPE and FFP10 data releases [PDF]

, 2021
Pratyush Pranav
openalex   +1 more source

Geochronology of the Whittlesey sedimentary succession, eastern England: The ‘Pompeii’ of the British late Middle Pleistocene to Holocene record

Journal of Quaternary Science, EarlyView.
Abstract The sedimentary succession at Whittlesey preserves a unique British late Middle Pleistocene to Holocene record back to a time equivalent to at least marine oxygen isotope stage 8 (ca. 250 ka). This study builds on previously published sedimentology, geochronology and palaeoecology results to establish 20 sedimentary facies associations, with ...
H. E. Langford, M. D. Bateman, R. M. Briant, D. J. Horne   +3 more
wiley   +1 more source