Results 51 to 60 of about 347,393 (310)

Data‐driven discovery of gene expression markers distinguishing pediatric acute lymphoblastic leukemia subtypes

Molecular Oncology, EarlyView.
This study investigates gene expression differences between two major pediatric acute lymphoblastic leukemia (ALL) subtypes, B‐cell precursor ALL, and T‐cell ALL, using a data‐driven approach consisting of biostatistics and machine learning methods. Following analysis of a discovery dataset, we find a set of 14 expression markers differentiating the ...
Mona Nourbakhsh, Nikola Tom, Anna Schrøder Lassen, Helene Brasch Lind Petersen, Ulrik Kristoffer Stoltze, Karin Wadt, Kjeld Schmiegelow, Matteo Tiberti, Elena Papaleo   +8 more
wiley   +1 more source

Comprehensive omics‐based classification system in adult patients with B‐cell acute lymphoblastic leukemia

Molecular Oncology, EarlyView.
The COMBAT classification system, developed through multi‐omics integration, stratifies adult patients with B‐cell acute lymphoblastic leukemia(B‐ALL) into three molecular subtypes with distinct surface antigen patterns, immune landscape, methylation patterns, biological pathways and prognosis.
Yang Song, Ting Liu, Qishan Hao, Qiuyun Fang, Xiaoyuan Gong, Yan Li, Zheng Tian, Hui Wei, Min Wang, Jianxiang Wang, Tao Cheng, Yingchang Mi   +11 more
wiley   +1 more source

Surrendering to and Transcending Ming 命 in the Analects, Mencius and Zhuangzi

Religions
This article examines the concept of ming 命 (mandate/command or fate/destiny) in the Analects, Mencius, and Zhuangzi, exploring its relationship to tian 天 (Heaven).
Ying Zhou
doaj   +1 more source

Comparison of global observations and trends of total precipitable water derived from microwave radiometers and COSMIC radio occultation from 2006 to 2013 [PDF]

Atmospheric Chemistry and Physics, 2018
We compare atmospheric total precipitable water (TPW) derived from the SSM/I (Special Sensor Microwave Imager) and SSMIS (Special Sensor Microwave Imager/Sounder) radiometers and WindSat to collocated TPW estimates derived from COSMIC (Constellation ...
S.-P. Ho, L. Peng, C. Mears, R. A. Anthes   +3 more
doaj   +1 more source

Measurement of the cosmic ray proton spectrum from 40 GeV to 100 TeV with the DAMPE satellite [PDF]

Science Advances, 2019
DAMPE satellite has directly measured the cosmic ray proton spectrum from 40 GeV to 100 TeV and revealed a new feature at about 13.6 TeV. The precise measurement of the spectrum of protons, the most abundant component of the cosmic radiation, is ...
Q. An, R. Asfandiyarov, P. Azzarello, P. Bernardini, X. Bi, M. Cai, J. Chang, D. Chen, H. Chen, J. Chen, W. Chen, M. Cui, T. Cui, H. Dai, A. D’Amone, A. De Benedittis, I. De Mitri, M. Di Santo, M. Ding, T. Dong, Y. Dong, Z. Dong, G. Donvito, D. Droz, J. Duan, K. Duan, D. D’Urso, R. Fan, Y. Fan, F. Fang, C. Feng, L. Feng, P. Fusco, V. Gallo, F. Gan, M. Gao, F. Gargano, K. Gong, Y. Gong, D. Guo, J. Guo, X. Guo, S. Han, Y. Hu, G. Huang, X. Y. Huang, Y. -. Huang, M. Ionica, W. Jiang, X. Jin, J. Kong, S. Lei, S. Li, W. Li, X. Li, X. Li, Y. Li, Y. Liang, Y. Liang, N. Liao, C. M. Liu, H. Liu, J. Liu, S. Liu, W. Liu, Y. Liu, F. Loparco, C. Luo, M. Ma, P. Ma, S. Ma, T. Ma, X. Ma, G. Marsella, M. Mazziotta, D. Mo, X. Niu, X. Pan, W. Peng, X. Peng, R. Qiao, J. Rao, M. Salinas, G. Shang, W. Shen, Z. Shen, Z. Shen, J. Song, H. Su, M. Su, Z. Sun, A. Surdo, X. Teng, A. Tykhonov, S. Vitillo, C. Wang, Hong Wang, H. Wang, J. Wang, L. Wang, Q. Wang, S. Wang, X. H. Wang, X. L. Wang, Y. Wang, Y. P. Wang, Y. Wang, Z. Wang, D. Wei, J. Wei, Y. F. Wei, S. Wen, D. Wu, J. Wu, L. Wu, S. Wu, X. Wu, K. Xi, Z. Xia, H. Xu, Z. Xu, Z. L. Xu, Z. Xu, G. Xue, H. Yang, P. Yang, Y. Q. Yang, Z. L. Yang, H. Yao, Y. Yu, Q. Yuan, C. Yue, J. Zang, F. Zhang, J. Zhang, J. Zhang, P. Zhang, S. X. Zhang, W. Zhang, Y. Zhang, Y. Zhang, Y. Zhang, Y. Zhang, Y. Zhang, Z. Zhang, Z. Zhang, H. Zhao, H. Zhao, X. Zhao, C. Zhou, Y. Zhou, X. Zhu, Y. Zhu, S. Zimmer   +153 more
semanticscholar   +1 more source

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

Molecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad, Mahmood Hachim, Tom Bertin, Karolina Penderecka, Rifat Hamoudi, Saif Khan, Rui Henrique, Natalie Bergmoser, Manit Arya, Kalle Sipila, Matteo Vietri Rudan, Asif Muneer, Aamir Ahmed   +12 more
wiley   +1 more source

Ground strains induced by the 2022 Hunga-Tonga volcanic eruption, observed by a 1500-m laser strainmeter at Kamioka, Japan

Earth, Planets and Space, 2023
In this study, we detected the horizontal ground strains induced by the atmospheric Lamb wave emitted from the 2022 eruption of the Tonga–Hunga Ha’apai undersea volcano, at an underground observatory in Kamioka, Japan.
Akiteru Takamori, Akito Araya, Kouseki Miyo, Tatsuki Washimi, Takaaki Yokozawa, Hideaki Hayakawa, Masatake Ohashi   +6 more
doaj   +1 more source

Comparison of COSMIC and COSMIC-2 Radio Occultation Refractivity and Bending Angle Uncertainties in August 2006 and 2021

Atmosphere, 2022
We compare the random error statistics (uncertainties) of COSMIC (Constellation Observing System for Meteorology, Ionosphere and Climate, C1) and COSMIC-2 (C2) radio occultation (RO) bending angles and refractivities for the months of August 2006 and ...
Richard Anthes, Jeremiah Sjoberg, Xuelei Feng, Stig Syndergaard   +3 more
doaj   +1 more source

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source

Three-dimensional earthward fast flow in the near-Earth plasma sheet in a sheared field: comparisons between simulations and observations [PDF]

Annales Geophysicae, 2009
Three-dimensional configuration of earthward fast flow in the near-Earth plasma sheet is studied using three-dimensional magnetohydrodynamics (MHD) simulations on the basis of the spontaneous fast reconnection model.
K. Kondoh, M. Ugai
doaj   +1 more source