Results 131 to 140 of about 14,844 (293)

Comprehensive genomic profiling of mucosal melanoma reveals novel fusion transcripts and dysregulation of cell‐cycle, MAPK, and PI3K pathways

The Journal of Pathology, EarlyView.
Abstract Mucosal melanomas (MMs) are rare, aggressive cancers with poor outcomes and limited response to standard therapies. A significant knowledge gap exists regarding their genomic landscape and corresponding druggable targets. This study explores this issue through a multi‐omic analysis, including whole exome‐, RNA‐, and targeted sequencing, of ...
Matilde Monti, Martina Brigida Romanello, Luca Agnelli, Matteo Orlandi, Luca Bertoli, Sara Picinoli, Irene Pezzali, Giulio Eugenio Mandelli, Daniela Medicina, Giovanni Ribaudo, Adele Busico, Elena Conca, Vilma Pellegrini, Piera Balzarini, Daniele Gallucci, Anna Di Matteo, Davide Lombardi, Claudia Ghigna, Giancarlo Pruneri, Alessandra Gianoncelli, Marzia Rossato, William Vermi   +21 more
wiley   +1 more source

Repeated Pleistocene Permafrost Episodes in the Western Pannonian Basin

Permafrost and Periglacial Processes, EarlyView.
ABSTRACT Concerning the study of past periglacial processes, the Pannonian Basin is a key area as it contains the southernmost frost polygons found in Central Europe. The presence or absence of permafrost is still, however, a matter of debate, and data on the timing of frost action are also scarce.
Krisztina Sebe, Ágnes Novothny, Gergely Surányi, Barbara Varga, László Fodor, Gábor Csillag   +5 more
wiley   +1 more source

Increasing urban flash flood risk attributable to both climate and development

Quarterly Journal of the Royal Meteorological Society, EarlyView.
A new event impact attribution methodology that combines convection‐permitting climate model data with flood inundation modelling was used for a five‐hour flash‐flooding event in the suburbs of Leeds in 2014. The results show increased urban flood extent due to both climate change (+16%) and increased urbanisation (+29%).
Daniel F. Cotterill, Dann Mitchell, Peter A. Stott, Paul Bates, Youtong Rong, Leanne Archer   +5 more
wiley   +1 more source

Evaluation and assimilation of Arctic Weather Satellite data in the AROME‐Arctic forecast system

Quarterly Journal of the Royal Meteorological Society, EarlyView.
The Arctic Weather Satellite (AWS), launched in August 2024, is a prototype for the future EPS–Sterna constellation of small satellites carrying an innovative microwave sounder. We present the first assessment of AWS in the regional AROME‐Arctic numerical weather prediction system, covering post‐launch calibration results and the impact of AWS ...
Stéphanie Guedj, Per Dahlgren, Máté Mile   +2 more
wiley   +1 more source

The Marvel of Gravitation — The Driving Force of Cosmic Evolution

Jiaqing Yan
openalex   +2 more sources

DNA as a quantum system in evolution. [PDF]

PLoS One
Garcia NA.
europepmc   +1 more source

Ontologies for Sustainability: Theoretical Challenges

Sustainable Development, EarlyView.
ABSTRACT The lack of sustainable practices in key sectors of human societies is a global concern, posing threats for the whole planet. This paper provides the first review of ontologies for sustainability efforts, outlining their roles in assessing and advancing such efforts. Section 2 outlines three major challenges associated with sustainability: (1)
Giorgio A. Ubbiali, Matthew C. Lange, Andrea Borghini   +2 more
wiley   +1 more source

The era of precision cosmology with voids. [PDF]

Astron Astrophys Rev
Contarini S, Verza G, Pisani A.
europepmc   +1 more source

Glocal Regenerative Viticulture: Exploring Sustainable Winemaking Strategies in Europe

Sustainable Development, EarlyView.
ABSTRACT The global wine industry is transforming due to climate change challenges. Glocalization is increasingly relevant in winemaking, where geographical and cultural diversity requires context‐specific solutions in the existing sustainability spectrum in viticulture.
Aleksandra N. Volkova, Ekaterina A. Ivanova, Aleksandr K. Vorobev, Flavio P. Martins, Michael E. Akim   +4 more
wiley   +1 more source

Black hole information turbulence and the Hubble tension. [PDF]

Sci Rep
Cabrera Fernández JL.
europepmc   +1 more source