Results 71 to 80 of about 3,102,022 (309)

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Evolution of cosmic string configurations [PDF]

Physical Review D, 1993
We extend and develop our previous work on the evolution of a network of cosmic strings. The new treatment is based on an analysis of the probability distribution of the end-to-end distance of a randomly chosen segment of left-moving string of given length.
Austin, Daren, Copeland, E. J., Kibble, T. W. B.   +2 more
openaire   +3 more sources

Cross‐Modal Denoising and Integration of Spatial Multi‐Omics Data with CANDIES

Advanced Science, EarlyView.
In this paper, we introduce CANDIES, which leverages a conditional diffusion model and contrastive learning to effectively denoise and integrate spatial multi‐omics data. We conduct extensive evaluations on diverse synthetic and real datasets, CANDIES shows superior performance on various downstream tasks, including denoising, spatial domain ...
Ye Liu, Wanpeng Zou, Yuekai Li, Jiayi Wang, Mingxuan Cai, Hongmin Cai   +5 more
wiley   +1 more source

Investigations of the degree of asymmetry across the dayside magnetopause under southward interplanetary magnetic field using GEOTAIL observations

Earth, Planets and Space
The magnetic reconnection environment around the dayside geomagnetopause under long-lasting southward interplanetary magnetic field (IMF) conditions is investigated using the in-situ observation by GEOTAIL satellite from 1994 to 2019.
Koji Kondoh, Shin-ya Nitta
doaj   +1 more source

Modified gravity with an exponential function of curvature

European Physical Journal C: Particles and Fields, 2020
The role of an exponential function of the scalar curvature in the modified gravity is analyzed. Two models are proposed. A toy model that complies with local and cosmological constraints and gives appropriate qualitative description of the cosmic ...
L. N. Granda
doaj   +1 more source

Cosmic evolution and metal aversion in superluminous supernova host galaxies [PDF]

, 2016
SS acknowledges support from the CONICYT-Chile FONDECYT Postdoctorado fellowship 3140534 and the Feinberg Graduate School. SS and FEB acknowledge support from Basal-CATA PFB-06/2007, and Project IC120009 'Millennium Institute of Astrophysics (MAS)' of ...
S. Schulze, S. Schulze, S. Schulze, T. Krühler, G. Leloudas, G. Leloudas, J. Gorosabel, J. Gorosabel, J. Gorosabel, A. Mehner, J. Buchner, J. Buchner, Seock-Sam Kim, E. Ibar, R. Amorín, R. Herrero-Illana, Joseph P. Anderson, F. Bauer, F. Bauer, F. Bauer, L. Christensen, M. Pasquale, A. U. Postigo, A. Gallazzi, J. Hjorth, N. Morrell, D. Malesani, M. Sparre, B. Stalder, A. Stark, C. Thöne, J. Wheeler   +31 more
semanticscholar   +1 more source

Highly Efficient and Environmentally Stable Radiative Cooling Fabric: Integrating Photoluminescence and Hierarchical Core–Shell Fibers

Advanced Science, EarlyView.
A scalable radiative cooling fabric engineered with a multi‐layer assembly core–shell structure and integrated photoluminescent materials is reported. The fabric exhibits remarkable environmental stability, including UV resistance, mechanical durability, hydrophobicity, stain resistance, thermal stability, and flame retardancy, demonstrating its ...
Hongtao Liu, Hui Li, Yining Wang, Wei Sun, Zhuan Chen, Yongping Hou, Yongmei Zheng, Xuejian Chen, Bin Yu   +8 more
wiley   +1 more source

Probing the gravitational wave background from cosmic strings with the alternative LISA-TAIJI network

European Physical Journal C: Particles and Fields, 2023
As one of the detection targets of all gravitational wave detectors today, the stochastic gravitational wave background (SGWB) provides an important means of understanding the evolution of our universe.
Bo-Rui Wang, Jin Li, He Wang
doaj   +1 more source

Test of the cosmic evolution using Gaussian processes [PDF]

, 2016
Much focus was on the possible slowing down of cosmic acceleration under the dark energy parametrization. In the present paper, we investigate this subject using the Gaussian processes (GP), without resorting to a particular template of dark energy.
Ming-Jian Zhang, Jun-qing Xia
semanticscholar   +1 more source

SpaMode: A Broadly Applicable Framework for Deciphering Spatial Multi‐Omics Using Multimodal Mixture of Disentangled Experts

Advanced Science, EarlyView.
SpaMode introduces a versatile framework for spatial multi‐omics integration across vertical, horizontal, and mosaic scenarios. By disentangling modality‐invariant and variant features through a mixture‐of‐experts mechanism, it adaptively reconfigures spatially heterogeneous signals.
Xubin Zheng, Xinlei Huang, Xiang Zhou, Dian Meng, Ziyue Qiao, Zhiyuan Yuan, Lixin Cheng   +6 more
wiley   +1 more source