Results 91 to 100 of about 6,718,063 (241)

Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy

open access: yesMolecular Oncology, EarlyView.
LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir   +9 more
wiley   +1 more source

Cost-effectiveness results.

open access: yes, 2019
Cost-effectiveness results.
Neil A. J. Ryan (6398243)   +5 more
core   +2 more sources

Optimization of seminal extracellular vesicle isolation protocols for cancer biomarker analysis using proteomic profiling

open access: yesMolecular Oncology, EarlyView.
This paper shows that size‐exclusion chromatography and sequential centrifugation applied to seminal plasma enrich for different populations of extracellular vesicles. This may significantly affect the detection and analysis of extracellular vesicle‐associated cancer biomarkers.
Elen Telumyan   +8 more
wiley   +1 more source

Endogenous Cost-Effectiveness Analysis in Health Care Technology Adoption [PDF]

open access: yes
Increased health care spending has been argued to be largely due to technological change. Cost-effectiveness analysis is the main tool used by private and public third-party payers to prioritize adoption of the new technologies responsible for this ...
Tomas Philipson, Anupam Jena
core  

Cost and cost-effectiveness of HIV/AIDS prevention strategies in developing countries: is there an evidence base?

open access: yes, 2003
Many donors and countries are striving to respond to the HIV/AIDS epidemic by implementing prevention programmes. However, the resources available for providing these activities relative to needs are limited.
Walker, Damian
core   +1 more source

Spatial heterogeneity of hotspot mutations and clonal relatedness in ovarian endometrioid carcinoma

open access: yesMolecular Oncology, EarlyView.
Spatially resolved analysis revealed heterogeneous distributions of selected cancer‐associated mutations within ovarian endometrioid carcinomas. Shared mutations between paired endometrial and ovarian tumors supported clonal relatedness. These findings highlight the value of sampling multiple tumor regions when interpreting molecular profiles ...
Takahito Ashihara   +10 more
wiley   +1 more source

Cost-effectiveness analysis of malaria interventions using disability adjusted life years: a systematic review

open access: yesCost Effectiveness and Resource Allocation, 2017
Background Malaria continues to be a public health problem despite past and on-going control efforts. For sustenance of control efforts to achieve the malaria elimination goal, it is important that the most cost-effective interventions are employed. This
Resign Gunda, Moses John Chimbari
doaj   +1 more source

COST-EFFECTIVENESS ANALYSIS OF THE IMPACTS ON INFECTION AND MORBIDITY ATTRIBUTABLE TO THREE CHEMOTHERAPY SCHEMES AGAINST SCHISTOSOMA JAPONICUM IN HYPERENDEMIC AREAS OF THE DONGTING LAKE REGION, CHINA

open access: yes, 2020
. A study was carried out in 8 villages endemic with S. japonicum in Hunan Province, China from 1998 to 2000 to evaluate the cost-effectiveness in preventing schistosome infection and related morbidity under three chemotherapy schemes: (1) 'clue ...
Control, Schistosome, Cost-Effectiveness
core  

Cost-effectiveness information.

open access: yes, 2019
Cost-effectiveness information.
Jonathan Price (3574760)   +4 more
core   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

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