Results 81 to 90 of about 6,718,063 (241)

Cost-effectiveness analysis.

, 2019
Cost-effectiveness analysis.
A. Hazra (1680568), S. Saha (1895374), S. Mondal (1585582), G. Shetty (6524324), R. Das (3115068), A. Porwal (6524327), S. Chandrashekar (6524318), L. Mohan (6524321), B. Varghese (2326159)   +8 more
core   +2 more sources

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

Molecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou, Niki Tzenaki, Anna Tsapara, Maria Tzardi, Evangelia A. Papakonstanti   +4 more
wiley   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

Molecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez, Rafael Pérez‐Díaz, Hugo Ramos‐Solano, Marina Garrido‐Casado, Vanessa C. Talayero, Miguel Vicente‐Manzanares   +5 more
wiley   +1 more source

Treatment of moderate acute malnutrition through community health volunteers is a cost‐effective intervention: Evidence from a resource‐limited setting

Maternal and Child Nutrition
Treatment outcomes for acute malnutrition can be improved by integrating treatment into community case management (iCCM). However, little is known about the cost‐effectiveness of this integrated nutrition intervention.
Patrick G. Ilboudo, Hermann Pythagore Pierre Donfouet, Calistus Wilunda, Bernardette Cichon, Daniel Tewoldeberhan, James Njiru, Emily Keane, Bonventure Mwangi, Elizabeth Mwaniki, Taddese Alemu Zerfu, Lilly Schofield, Lucy Maina, Edward Kutondo, Olivia Agutu, Peter Okoth, Judith Raburu, Daniel Kavoo, Lydia Karimurio, Charles Matanda, Alex Mutua, Grace Gichohi, Elizabeth Kimani‐Murage   +21 more
doaj   +1 more source

Cost-effectiveness plane and incremental cost-effectiveness acceptability curve KATZ-15.

, 2018
Cost-effectiveness plane and incremental cost-effectiveness acceptability curve KATZ-15.
Irma H. J. Everink (4898452), Jolanda C. M. van Haastregt (4898449), Jos M. G. A. Schols (3228828), Silvia M. A. A. Evers (643477), Gertrudis I. J. M. Kempen (583581)   +4 more
core   +1 more source

Bridging the gap: a genetically validated avian chorioallantoic membrane platform for investigation of spontaneous circulating tumor cells

Molecular Oncology, EarlyView.
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth, Rui P. L. Neves, Julia Geheb, Christian Ballmeyer, Nathalie Gaßmann, Kiki C. Andree, Monica Sudarsanam, Christiane Driemel, Celine Örencik, Andrè Franken, Eslam Elmaghraby, Sven H. Loosen, Roderburg Christoph, Sebastian Schoelch, Hans Neubauer, Wolfram T. Knoefel, Nikolas H. Stoecklein, Georg Fluegen   +17 more
wiley   +1 more source

Cost‐effectiveness analysis of the artificial intelligence diagnosis support system for early gastric cancers

DEN Open
Objectives The introduction of artificial intelligence into the medical field has improved the diagnostic capabilities of physicians. However, few studies have analyzed the economic impact of employing artificial intelligence technologies in the clinical
Shion Yonazu, Tsuyoshi Ozawa, Tamiji Nakanishi, Kentaro Ochiai, Junichi Shibata, Hiroyuki Osawa, Toshiaki Hirasawa, Yusuke Kato, Hisao Tajiri, Tomohiro Tada   +9 more
doaj   +1 more source

An Analysis of the Cost and Cost-Effectiveness of Faculty Development for Online Teaching

Online Learning, 2014
This article presents the results of a national study of 39 higher education institutions that collected information about their cost measures used to evaluate faculty development for online teaching as well as decisions they would make to expand, keep ...
Katrina A. Meyer
doaj   +1 more source

Cost-effectiveness threshold based on the pre-PC cost-effectiveness trend line.

, 2018
Cost-effectiveness threshold based on the pre-PC cost-effectiveness trend line.
Maurílio de Souza Cazarim (2838158), Leonardo Régis Leira Pereira (492901)   +1 more
core   +1 more source