Results 91 to 100 of about 29,557,581 (269)

Radiofrequency ablation using the ThermoCool SmartTouch Catheter guided by ablation index versus antiarrhythmic drugs in atrial fibrillation treatment in China: a cost-consequence analysis

Journal of Comparative Effectiveness Research
Aim: To evaluate the costs and consequences of two front-line atrial fibrillation (AF) treatments from Chinese healthcare system perspective: radiofrequency catheter ablation (RFCA) using ThermoCool SmartTouch Catheter guided by Ablation Index (STAI ...
Biqi Zhang, Jie Han, Dongchen Zhou, Jiajia Jiang, Jiawei Zhong, Yunlong Lu, Chenyu Zuo, Xingwei Lu, Jianwei Xuan, Aohan Zu, Yuxian He, Xingang Sun, Lu Chen, Liangrong Zheng   +13 more
doaj   +1 more source

Overcoming platinum resistance by the disulfiram metabolite CuET in novel preclinical models of human carcinomas

Molecular Oncology, EarlyView.
Cisplatin‐resistant cancer cells survive DNA‐damaging platinum‐based treatment yet remain sensitive to CuET‐induced proteotoxic stress. The distinct mechanism of action allows CuET to overcome and eliminate cisplatin‐resistant tumour cells, unless highly expressed metallothioneins (MTs) interfere with CuET, thereby highlighting MT levels as candidate ...
Stefanos Arampatzis, Tereza Buchtová, Jirina Bartkova, Marie Lund Bay, Christoffer Lynge Halvorsen, Zuzana Machacova, Zdenek Skrott, Martin Mistrik, Ekaterina Dulina, Miguel Andujar‐Sanchez, Estrid Høgdall, Tine Henrichsen Schnack, Claus Høgdall, Berit Jul Mosgaard, Marie Boennelycke, Jacob Brink Laursen, Allan Jensen, Susanne K. Kjær, Tuula Kallunki, Robert Strauss, Jiri Bartek   +20 more
wiley   +1 more source

Cost-consequence analysis of influenza vaccination among the staff of a large teaching hospital in Rome, Italy: A pilot study [PDF]

, 2019
Flu vaccination, as well as being effective to prevent seasonal influenza, decreases staff illness and absenteeism and reduces costs resulting from loss of productivity. Despite the effectiveness of flu vaccination, the seasonal coverage among healthcare
Americo Cicchetti, Walter Ricciardi (15986), Andrea Barbara, Filippo Berloco, Andrea Barbara (7866200), Daniele Piacentini (7866206), Andrea Cambieri, Andrea Gentili (3425243), Patrizia Laurenti, Laurenti, Patrizia, Berloco, Filippo, Andrea Tamburrano (7866197), Piacentini, Daniele, Daniele Piacentini, Daniele Ignazio La Milia (7866203), Patrizia Laurenti (7866218), Vittoria Colamesta, Ricciardi, Walter, Andrea Gentili, Cicchetti, Americo, Gentili, Andrea, Sergio Riccardo Mastrodonato (7866212), Barbara, Andrea, Americo Cicchetti (4041329), Filippo Berloco (5508689), Roberta Galluzzi (7866209), Walter Ricciardi, Daniele Ignazio La Milia, Andrea Tamburrano, Andrea Cambieri (7866215), Vittoria Colamesta (4966333), Roberta Galluzzi, Cambieri, Andrea, Sergio Riccardo Mastrodonato   +33 more
core   +1 more source

An outer membrane vesicle‐associated two‐track model for enterotoxigenic Bacteroides fragilis oncogenesis

Molecular Oncology, EarlyView.
Enterotoxigenic Bacteroides fragilis is a gut bacterium linked to bowel cancer. We propose that its toxin acts along two routes: at the cell surface, cutting the adhesion protein E‐cadherin and triggering inflammation; and inside the cell, delivered by bacterial vesicles, switching on NOD1 and cancer stem cell programs.
Kangchan Choi, Sang‐Hyeon Yoo, Ki‐Jong Rhee   +2 more
wiley   +1 more source

Micro-costing and a cost-consequence analysis of the 'Girls Active' programme: A cluster randomised controlled trial.

PLoS ONE, 2019
Physical inactivity has been identified as a leading risk factor for premature mortality globally, and adolescents, in particular, have low physical activity levels. Schools have been identified as a setting to tackle physical inactivity.
Joanna M Charles, Deirdre M Harrington, Melanie J Davies, Charlotte L Edwardson, Trish Gorely, Danielle H Bodicoat, Kamlesh Khunti, Lauren B Sherar, Thomas Yates, Rhiannon Tudor Edwards   +9 more
doaj   +1 more source

Cost-consequence model comparing eltrombopag and romiplostim in pediatric patients with chronic immune thrombocytopenia

, 2018
Gabriel Tremblay,1 Mike Dolph,1 Menaka Bhor,2 Qayyim Said,2 Anuja Roy,2 Brian Elliott,3 Andrew Briggs4 1Health Economics, Purple Squirrel Economics, New York, NY, USA; 2Health Economics and Outcomes Research, Novartis Pharmaceuticals, East 
Said Q, Tremblay G, Briggs A, Roy A, Bhor M, Elliott B, Dolph M   +6 more
core  

Cost-effectiveness and cost-benefit analysis of governance and anti-corruption activities [PDF]

, 2014
Cost-effectiveness and cost-benefit analysis methods are currently underutilised in evaluations of governance and anti-corruption reforms in developing countries.
Johnsøn, Jesper
core  

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Cost-consequence Analysis of Secukinumab vs Adalimumab in Moderate-to-severe Hidradenitis Suppurativa

Actas Dermo-Sifiliográficas
Background and objective: Hidradenitis suppurativa (HS) is a chronic inflammatory skin disease. Treatment for moderate-to-severe HS includes biologic therapies (adalimumab and secukinumab), resulting in increased disease management costs.
A. Martorell, A. Molina-Leyva, A. Jiménez Morales, C. Blanch   +3 more
doaj   +1 more source

Cost-utility analysis: Incremental cost-effectiveness ratio (ICER)—base case.

, 2019
Cost-utility analysis: Incremental cost-effectiveness ratio (ICER)—base case.
Frauke Becker (2836922), Denise Howel (16468), Catherine Haighton (2157001), Martin White (16466), Andrew Bryant (5704967), Terry Aspray (6194804), Luke Vale (3435356), Elaine McColl (533649), Suzanne Moffatt (16467), Sarah Lawson (6194801), Melanie Steer (6194798), Eugene M. G. Milne (2215138)   +11 more
core   +1 more source