Results 71 to 80 of about 2,748,163 (380)

NanoCMSer: a consensus molecular subtype stratification tool for fresh‐frozen and paraffin‐embedded colorectal cancer samples

Molecular Oncology, EarlyView.
Consensus molecular subtypes (CMS1‐4) have been identified to study colorectal cancer heterogeneity and serve as potential biomarkers. In this study, we developed and evaluated NanoCMSer, a NanoString‐based classifier using 55 genes, optimized for FF and FFPE to facilitate the clinical evaluation of CMS subtyping.
Arezo Torang, Simone van de Weerd, Veerle Lammers, Sander van Hooff, Inge van den Berg, Saskia van den Bergh, Miriam Koopman, Jan N. IJzermans, Jeanine M. L. Roodhart, Jan Koster, Jan Paul Medema   +10 more
wiley   +1 more source

Cost-effectiveness analysis of FOLFOX4 and sorafenib for the treatment of advanced hepatocellular carcinoma in China

Cost Effectiveness and Resource Allocation, 2018
ObjectivesHepatocellular carcinoma (HCC) is a leading cause of cancer-related deaths globally. In China, sorafenib and oxaliplatin plus infusional-fluorouracil/leucovorin (FOLFOX4) are approved for the systemic treatment of advanced HCC.
S. Qin, E. Kruger, S. Tan, Shuqun Cheng, Nanya Wang, Jun Liang   +5 more
semanticscholar   +1 more source

Cost-effectiveness analysis for trigeminal neuralgia: Cyberknife vs microvascular decompression

Neuropsychiatric Disease and Treatment, 2008
Rosanna Tarricone1, Giovanni Aguzzi1, Francesco Musi1, Laura Fariselli2, Andrea Casasco31Economic Evaluation Area, CERGAS Centre for Research on Healthcare Management-Bocconi University, Milan, Italy; 2Radiotherapy Department, Carlo Besta National ...
Rosanna Tarricone, Giovanni Aguzzi, Francesco Musi, Laura Fariselli, Andrea Casasco   +4 more
doaj  

Principal Moment Analysis [PDF]

arXiv, 2020
Principal Moment Analysis is a method designed for dimension reduction, analysis and visualization of high dimensional multivariate data. It generalizes Principal Component Analysis and allows for significant statistical modeling flexibility, when approximating an unknown underlying probability distribution, by enabling direct analysis of general ...
arxiv  

Addressing persistent challenges in digital image analysis of cancer tissue: resources developed from a hackathon

Molecular Oncology, EarlyView.
Large multidimensional digital images of cancer tissue are becoming prolific, but many challenges exist to automatically extract relevant information from them using computational tools. We describe publicly available resources that have been developed jointly by expert and non‐expert computational biologists working together during a virtual hackathon
Sandhya Prabhakaran, Clarence Yapp, Gregory J. Baker, Johanna Beyer, Young Hwan Chang, Allison L. Creason, Robert Krueger, Jeremy Muhlich, Nathan Heath Patterson, Kevin Sidak, Damir Sudar, Adam J. Taylor, Luke Ternes, Jakob Troidl, Xie Yubin, Artem Sokolov, Darren R. Tyson   +16 more
wiley   +1 more source

Cost-effectiveness analysis of corticosteroid inhaler devices in primary care asthma management: A real world observational study

ClinicoEconomics and Outcomes Research, 2010
Linda Kemp1, John Haughney2, Neil Barnes3, Erika Sims1, Julie von Ziegenweidt1, Elizabeth V Hillyer1, Amanda J Lee4, Alison Chisholm1, David Price1,21Research in Real Life Ltd, Old Winery Business Park, Cawston, Norwich, UK; 2Centre of Academic Primary ...
Linda Kemp, John Haughney, Neil Barnes, et al   +3 more
doaj  

A trial-based economic evaluation of the Restore4Stroke self-management intervention compared to an education-based intervention for stroke patients and their partners

BMC Health Services Research, 2020
Background Since stroke survivors are increasingly responsible for managing stroke-related changes in their own health and lifestyle, self-management skills are required.
Ghislaine A. P. G. van Mastrigt, Mitchel van Eeden, Caroline M. van Heugten, Nienke Tielemans, Vera P. M. Schepers, Silvia M. A. A. Evers   +5 more
doaj   +1 more source

Conservation cost‐effectiveness: a review of the evidence base

Conservation Science and Practice, 2021
Prioritizing conservation interventions based on their cost‐effectiveness may enhance global conservation impact. To do this prioritization, conservation decision‐makers need evidence of what works where and how much it costs.
Thomas Pienkowski, Carly Cook, Megha Verma, Luis Roman Carrasco   +3 more
doaj   +1 more source

Cost-effectiveness analysis in oncology

Annals of Oncology, 1998
Physicians are faced with a burgeoning literature of economic studies. However, most physicians have little training in evaluating economic research. Economic studies involve a comparison of the costs and benefits of alternative treatment options. To be of use for medical decision making, they should meet appropriate methodological standards.
W. K. Evans, Doug Coyle, Craig C. Earle
openaire   +2 more sources

Robust acute myeloid leukemia engraftment in humanized scaffolds using injectable biomaterials and intravenous xenotransplantation

Molecular Oncology, EarlyView.
Patient‐derived xenografts (PDXs) can be improved by implantation of a humanized niche. We tested different biomaterials and approaches, and demonstrate that the combination of an injectable biomaterial for scaffold creation plus an intravenous route for acute myeloid leukemia (AML) xenotransplantation provide the most convenient and robust approach to
Daniel Busa, Zdenka Herudkova, Jan Hyl, Jakub Vlazny, Filip Sokol, Kvetoslava Matulova, Adam Folta, Jakub Hynst, Lucy Vojtova, Leos Kren, Martin Repko, Zdenek Racil, Jiri Mayer, Martin Culen   +13 more
wiley   +1 more source