Results 91 to 100 of about 6,812,483 (357)

Low‐cost tools mitigate climate change during reproduction in an endangered marine ectotherm [PDF]

open access: bronze, 2021
Leo J. Clarke   +6 more
openalex   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

open access: yesMolecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg   +43 more
wiley   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

Deep Learning Based Characterization of Cold-Water Coral Habitat at Central Cantabrian Natura 2000 Sites Using YOLOv8

open access: yesJournal of Marine Science and Engineering
Cold-water coral (CWC) reefs, such as those formed by Desmophyllum pertusum and Madrepora oculata, are vital yet vulnerable marine ecosystems (VMEs).
Alberto Gayá-Vilar   +5 more
doaj   +1 more source

Review of the evidence for the potential impact and feasibility of substituting saturated fat in the New Zealand diet

open access: yesAustralian and New Zealand Journal of Public Health, 2013
Objective: To estimate the potential impact on cardiovascular health of modifying dietary intake of saturated fat across the New Zealand population, and whether this would be appropriate and feasible.
Rachel H. Foster, Nick Wilson
doaj   +1 more source

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

open access: yesMolecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris   +10 more
wiley   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

Identification of indicators of antibiotic pollution in typical karst groundwater in southwestern China

open access: yes地质科技通报
Objective The karst area in southwestern China is one of the three concentrated karst distribution areas in the world. Karst groundwater is highly susceptible to pollution from the surface due to the unique structure of aquifers.
Fuyang HUANG   +5 more
doaj   +1 more source

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