Results 71 to 80 of about 6,026,414 (311)

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

open access: yesFEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

Cost-effectiveness acceptability curves.

open access: yes, 2022
Willingness-to-pay ($) is shown with percent cost-effectiveness. The dashed line is a willingness-to-pay threshold (WTP) of $50,000/QALY and the percent cost effectiveness is 50.3% at a WTP of $50,000/QALY. Abbreviations. WTP, Willingness-to-pay.
Shota Saito (287377)   +3 more
core   +1 more source

Simple and Rapid Device for Mercury Detection Based on The Formation of Mercury(II)-Dithizonate on Polytetrafluoroethylene (PTFE) Membrane [PDF]

open access: yesJournal of Pure and Applied Chemistry Research, 2019
A new analytical device for mercury detection has been developed by doping dithizone on to hydrophobic PTFE (polytetrafluoroethylene) membrane to form a blue dithizone membrane which instantaneously changed to orange color of mercury(II)-dithizonate ...
Hermin Sulistyarti   +4 more
doaj  

Metode Spektrofotometri Secara Tidak Langsung untuk Penentuan Merkuri(II) berdasarkan Pembentukan Kompleks Biru Iodium-Amilum

open access: yesAlchemy, 2019
Metode spektrofotometri secara tidak langsung telah dikembangkan untuk analisis merkuri(II) berdasarkan perbedaan absorbansi kompleks biru amilum-iodium antara larutan sampel yang mengandung ion merkuri(II) dan larutan blanko yang tidak mengandung ion ...
Hermin Sulistyarti   +3 more
doaj   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

open access: yesMolecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou   +4 more
wiley   +1 more source

Cost accounting prepared by Hadley editorial staff.

open access: yes, 1953
Cost accounting prepared by Hadley editorial ...
Cost Fabrieksboekh
core  

Burden and magnitude of risk in HIV/AIDS in the Colombian health system: a real-world data approach

open access: yesInfectio, 2021
Aim: To assess the epidemiological situation of people living with HIV and AIDS (PLWHA) in the municipalities and regions of Colombia in 2018. Materials and methods: A cross-sectional study was conducted with secondary data from the High-Cost Diseases ...
Silvia Juliana Trujillo-Cáceres
doaj   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

open access: yesMolecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic   +10 more
wiley   +1 more source

Preliminary Testing of the Discussion of Patient Life Goals Patient-Reported Outcome Measure for Dialysis Facilities

open access: yesKidney Medicine
Rationale & Objectives: To test a new patient-reported outcome measure that assesses end-stage kidney disease (ESKD) maintenance dialysis patients’ experience with life goals discussions with their dialysis facility care team.
Claudia Dahlerus   +14 more
doaj   +1 more source

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