Results 71 to 80 of about 11,040,705 (306)

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Russell Kane: Comic chameleon [PDF]

open access: yes, 2013
Two years after winning the Edinburgh Comedy Award, Russell Kane has carved out a successful niche straddling the divide between high and low culture.
Friedman, S.
core   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Engine Data Interpretation System (EDIS), phase 2 [PDF]

open access: yes
A prototype of an expert system was developed which applies qualitative constraint-based reasoning to the task of post-test analysis of data resulting from a rocket engine firing. Data anomalies are detected and corresponding faults are diagnosed. Engine
Cost, Thomas L., Hofmann, Martin O.
core   +1 more source

What is Cost? [PDF]

open access: yes, 2010
Two-page paper on the notion of cost of groups and measured equivalence relations to appear in the "What is?" series in the Notices of the AMS.Comment: 2 ...
Gaboriau, Damien
core   +2 more sources

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

Coronary revascularization (Examples from the world and Turkey)

open access: yesTürk Kardiyoloji Derneği Arşivi, 2014
Objectives: In this article, our aims were to analyze and assess the data related to coronary revascularization rates, particularly in recent years.
Yücel Balbay   +4 more
doaj   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

Cost‐effectiveness of asthma clinic approach in the management of chronic asthma in Australia

open access: yesAustralian and New Zealand Journal of Public Health, 2013
Objectives: To compare cost‐effectiveness of an asthma clinic that would provide education, promotion of self‐monitoring of symptoms, regular review of treatment by a medical practitioner and a written asthma action plan to current practice in Australia.
Vittal Mogasale, Theo Vos
doaj   +1 more source

Metode Spektrofotometri Secara Tidak Langsung untuk Penentuan Merkuri(II) berdasarkan Pembentukan Kompleks Biru Iodium-Amilum

open access: yesAlchemy, 2019
Metode spektrofotometri secara tidak langsung telah dikembangkan untuk analisis merkuri(II) berdasarkan perbedaan absorbansi kompleks biru amilum-iodium antara larutan sampel yang mengandung ion merkuri(II) dan larutan blanko yang tidak mengandung ion ...
Hermin Sulistyarti   +3 more
doaj   +1 more source

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