Results 51 to 60 of about 4,719,811 (314)

Enhancing Hediste diversicolor aquaculture production: Density and feeding rate as key variables for intensive production management

open access: yesJournal of the World Aquaculture Society
This study analyzes the effect of density on growth and feeding rate in Hediste diversicolor. In a first trial, specimens ranging in size from 10 to 500 mg were fed for 15 days at apparent satiety at eight stocking densities ranging from 500 to 16,000 ...
F. Aguado‐Giménez   +2 more
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Conference Proceedings: 1st International Conference on Nanofluids (ICNf2019), 2nd European Symposium on Nanofluids (ESNf2019) [PDF]

open access: yes, 2019
Conference proceedings of the 1st International Conference on Nanofluids (ICNf2019) and 2nd European Symposium on Nanofluids (ESNf2019), 26-28 June 2019 in Castelló (Spain), organized by Nanouptake Action (CA15119) and Universitat Jaume
Nanouptake COST Action CA, 15119
core   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

Prescription and the cost of laboratory tests for patients admitted to two hospitals of Kashan University of Medical Sciences in the Covid 19 pandemic

open access: yesPayesh, 2022
Objective (s): Laboratory tests, despite their essential role in the diagnosis and management of many diseases, are often costly. Therefore, this study investigated the prescription and the cost of tests for patients admitted to two hospitals of Kashan ...
Razieh Eghtesadi   +3 more
doaj  

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

The Role of Marketplace Policy on Welcome Mat Effects for Children Eligible for Medicaid or the Children’s Health Insurance Program

open access: yesInquiry: The Journal of Health Care Organization, Provision, and Financing, 2020
The Affordable Care Act (ACA) required coordination between Marketplaces, Medicaid, and the Children’s Health Insurance Program (CHIP) in an effort to streamline application processes and improve enrollment.
Julie L. Hudson PhD, Asako S. Moriya PhD
doaj   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

open access: yesMolecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel   +12 more
wiley   +1 more source

Independent predictors of quality of life in patients with chronic heart failure

open access: yesRevista de la Facultad de Ciencias Médicas de Córdoba
Introduction: Objective measurement of Health-Related Quality of Life (HRQoL) has proven useful in evaluating the effectiveness of medical management and its potential as a predictor of mortality and rehospitalization in patients with heart failure (HF).
Lyda Z Rojas   +5 more
doaj   +1 more source

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

open access: yesMolecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi   +14 more
wiley   +1 more source

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