Results 91 to 100 of about 11,040,705 (306)
FEBS Open Bio, EarlyView.Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn +4 more
wiley +1 more source
Kidney MedicineRationale & Objectives: To test a new patient-reported outcome measure that assesses end-stage kidney disease (ESKD) maintenance dialysis patients’ experience with life goals discussions with their dialysis facility care team.
Claudia Dahlerus +14 more
doaj +1 more source
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
FEBS Open Bio, EarlyView.We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source
SYSTEM OF INDICATORS FOR MONITORING THE ECONOMIC SECURITY IN THE REGION
Стратегические решения и риск-менеджмент, 2014 This article describes the process of designing system to minimize risks in order to construct the algorithm for monitoring, analyzing and evaluating the economic security in the region.
I. Е. Denezhkina, D. А. Suzdaleva
doaj +1 more source
What Does It Cost To Guarantee Returns? [PDF]
The financial crisis has dramatically demonstrated how a collapse in equity prices can decimate retirement accounts. The crisis highlights the fragility of existing 401(k) plans as the only supplement to Social Security and has sparked proposals to ...
Alex Golub-Sass +3 more
core +1 more source
Cost Escalation in Nuclear Power [PDF]
, 1978 This report is concerned with the escalation of capital costs of nuclear central station power plants between the early 1960s and the present. The report presents an historical overview of the development of the nuclear power industry and cost escalation
Montgomery, W. David, Quirk, James P.
core
FEBS Open Bio, EarlyView.This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake +4 more
wiley +1 more source
Feature Selection and Predictors of Falls with Foot Force Sensors Using KNN-Based Algorithms
Sensors, 2015 The aging process may lead to the degradation of lower extremity function in the elderly population, which can restrict their daily quality of life and gradually increase the fall risk.
Shengyun Liang +6 more
doaj +1 more source
Low cost instrumentation amplifier [PDF]
, 1974 Amplifier can be used for many applications requiring high input impedance and common mode rejection, low drift, and gain accuracy on order of one percent. Performance of inexpensive amplifier approaches that of some commercial instrumentation amplifiers
Sturman, J. C.
core +1 more source