Results 81 to 90 of about 6,026,414 (311)
Molecular Oncology, EarlyView.Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez +5 more
wiley +1 more source
Molecular Oncology, EarlyView.We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth +17 more
wiley +1 more source
Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy
Molecular Oncology, EarlyView.LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir +9 more
wiley +1 more source
Passive and active control systems for adaptive glazing facades and envelopes
, 2015 This book is based upon work from COST Action TU 1403 adaptive facade network, supported by COST (European Cooperation in Science and Technology). COST (European Cooperation in Science and Technology) is a pan-European intergovernmental framework.
AMADIO, CLAUDIO +3 more
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Resultados del informe de aseguramiento de proyectos de infraestructura pública El Salvador, proceso 1 [PDF]
, 2017 SIGLAS Y ACRÓNIMOS. OBJETIVOS DEL ESTUDIO DE ASEGURAMIENTO. ASEGURAMIENTO. Selección de las entidades propietarias, instituciones públicas. Selección de proyectos a asegurar. Procedimiento de búsqueda de información. Información proactiva.
CoST El Salvador
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Molecular Oncology, EarlyView.This paper shows that size‐exclusion chromatography and sequential centrifugation applied to seminal plasma enrich for different populations of extracellular vesicles. This may significantly affect the detection and analysis of extracellular vesicle‐associated cancer biomarkers.
Elen Telumyan +8 more
wiley +1 more source
Spatial heterogeneity of hotspot mutations and clonal relatedness in ovarian endometrioid carcinoma
Molecular Oncology, EarlyView.Spatially resolved analysis revealed heterogeneous distributions of selected cancer‐associated mutations within ovarian endometrioid carcinomas. Shared mutations between paired endometrial and ovarian tumors supported clonal relatedness. These findings highlight the value of sampling multiple tumor regions when interpreting molecular profiles ...
Takahito Ashihara +10 more
wiley +1 more source
Report of Citizens' Committee on the Cost of Living / with a preface by D.B. Copland.
, 1919 Cover title.; Electronic reproduction. Canberra, A.C.T.
Citizens' Committee on the Cost of Living (Hobart, Tas.)
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, 2018 Cost-effectiveness analyses and model economic evaluations–health effects, costs, cost-effectiveness ratios and probabilities of cost-effectiveness.
Gunhild von Amsberg (2862761) +4 more
core +1 more source